Aurora kinase A, a synthetic lethal target for precision cancer medicine

por Mou, Pui Kei, Yang, Eun Ju, Shi, Changxiang, Ren, Guowen, Tao, Shishi, Shim, Joong Sup
Publicado 2021

MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism

por Ren, Guowen, Yang, Eun Ju, Tao, Shishi, Mou, Pui Kei, Pu, Yue, Chen, Li-Jie, Shim, Joong Sup
Publicado 2023

Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT

por Liu, Yifan, Yang, Eun Ju, Shi, Changxiang, Mou, Pui Kei, Zhang, Baoyuan, Wu, Changjie, Lyu, Junfang, Shim, Joong Sup
Publicado 2020

Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics

por Lyu, Junfang, Yang, Eun Ju, Zhang, Baoyuan, Wu, Changjie, Pardeshi, Lakhansing, Shi, Changxiang, Mou, Pui Kei, Liu, Yifan, Tan, Kaeling, Shim, Joong Sup
Publicado 2020

ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones

por Tao, Shishi, Yang, Eun Ju, Zong, Guanghui, Mou, Pui Kei, Ren, Guowen, Pu, Yue, Chen, Liang, Kwon, Ho Jeong, Zhou, Jianhong, Hu, Zhijian, Khosravi, Arman, Zhang, Qingyang, Du, Yuchun, Shi, Wei Q., Shim, Joong Sup
Publicado 2023