Population pharmacokinetics of azithromycin and chloroquine in healthy adults and paediatric malaria subjects following oral administration of fixed-dose azithromycin and chloroqui...

por Zhao, Qinying, Tensfeldt, Thomas G, Chandra, Richa, Mould, Diane R
Publicado 2014

Population PK and Exposure–Response Relationships for the Antibody–Drug Conjugate Brentuximab Vedotin in CTCL Patients in the Phase III ALCANZA Study

por Suri, Ajit, Mould, Diane R., Liu, Yi, Jang, Graham, Venkatakrishnan, Karthik
Publicado 2018

Pharmacokinetic and Pharmacodynamic Effects of Oral CXA‐10, a Nitro Fatty Acid, After Single and Multiple Ascending Doses in Healthy and Obese Subjects

por Garner, Rachel M., Mould, Diane R., Chieffo, Carla, Jorkasky, Diane K.
Publicado 2019

Population Pharmacokinetics of Brentuximab Vedotin in Adult and Pediatric Patients With Relapsed/Refractory Hematologic Malignancies: Model‐Informed Hypothesis Generation for Pedia...

por Suri, Ajit, Mould, Diane R., Song, Gregory, Kinley, Judith, Venkatakrishnan, Karthik
Publicado 2020

A Prospective Population Pharmacokinetic Analysis of Sapropterin Dihydrochloride in Infants and Young Children with Phenylketonuria

por Qi, Yulan, Mould, Diane R., Zhou, Huiyu, Merilainen, Markus, Musson, Donald G.
Publicado 2014

Increased Induction Infliximab Clearance Predicts Early Antidrug Antibody Detection

por Eser, Alexander, Reinisch, Walter, Schreiber, Stefan, Ahmad, Tariq, Boulos, Suliman, Mould, Diane R.
Publicado 2020

Limited Systemic Exposure with Topical Glycopyrronium Tosylate in Primary Axillary Hyperhidrosis

por Pariser, David M., Lain, Edward L., Mamelok, Richard D., Drew, Janice, Mould, Diane R.
Publicado 2021

Model Informed Precision Dosing Tool Forecasts Trough Infliximab and Associates with Disease Status and Tumor Necrosis Factor-Alpha Levels of Inflammatory Bowel Diseases

por Primas, Christian, Reinisch, Walter, Panetta, John C., Eser, Alexander, Mould, Diane R., Dervieux, Thierry
Publicado 2022

Population pharmacokinetics of pevonedistat alone or in combination with standard of care in patients with solid tumours or haematological malignancies

por Faessel, Hélène M., Mould, Diane R., Zhou, Xiaofei, Faller, Douglas V., Sedarati, Farhad, Venkatakrishnan, Karthik
Publicado 2019

Global population pharmacokinetics of the investigational Aurora A kinase inhibitor alisertib in cancer patients: rationale for lower dosage in Asia

por Zhou, Xiaofei, Mould, Diane R., Takubo, Takatoshi, Sheldon‐Waniga, Emily, Huebner, Dirk, Milton, Ashley, Venkatakrishnan, Karthik
Publicado 2017

Individualized Dosing of Therapeutic Monoclonal Antibodies—a Changing Treatment Paradigm?

por Strik, Anne S., Wang, Yow-Ming C., Ruff, Laura E., Yashar, William, Messmer, Bradley T., Mould, Diane R.
Publicado 2018

Population Pharmacokinetics and Exposure‐Safety Relationships of Alisertib in Children and Adolescents With Advanced Malignancies

por Zhou, Xiaofei, Mould, Diane R., Yuan, Ying, Fox, Elizabeth, Greengard, Emily, Faller, Douglas V., Venkatakrishnan, Karthik
Publicado 2022

Exposure–response characterization of tofacitinib efficacy in moderate to severe ulcerative colitis: Results from a dose‐ranging phase 2 trial

por Mukherjee, Arnab, Hazra, Anasuya, Smith, Mike K., Martin, Steven W., Mould, Diane R., Su, Chinyu, Niezychowski, Wojciech
Publicado 2018

Population Pharmacokinetic Modeling and Exposure–Response Assessment for the Antibody‐Drug Conjugate Brentuximab Vedotin in Hodgkin's Lymphoma in the Phase III ECHELON‐1 Study...

por Suri, Ajit, Mould, Diane R., Song, Gregory, Collins, Graham P., Endres, Christopher J., Gomez‐Navarro, Jesús, Venkatakrishnan, Karthik
Publicado 2019

Pharmacokinetics, pharmacodynamics, and safety of clevidipine after prolonged continuous infusion in subjects with mild to moderate essential hypertension

por Smith, William B., Marbury, Thomas C., Komjathy, Steven F., Sumeray, Mark S., Williams, Gregory C., Hu, Ming-yi, Mould, Diane R.
Publicado 2012

Differential analysis of transient increases of serum cTnI in response to handling in rats

por Mikaelian, Igor, Dunn, Michael E, Mould, Diane R, Hirkaler, Gerard, Geng, Wanping, Coluccio, Denise, Nicklaus, Rosemary, Singer, Thomas, Reddy, Micaela
Publicado 2013

Effect of alisertib, an investigational aurora a kinase inhibitor on the QTc interval in patients with advanced malignancies

por Zhou, Xiaofei, Nemunaitis, John, Pant, Shubham, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Craig Lockhart, A., Goodman, Daniel, Huebner, Dirk, Mould, Diane R., Venkatakrishnan, Karthik
Publicado 2017

Approaches to handling missing or “problematic” pharmacology data: Pharmacokinetics

por Irby, Donald J., Ibrahim, Mustafa E., Dauki, Anees M., Badawi, Mohamed A., Illamola, Sílvia M., Chen, Mingqing, Wang, Yuhuan, Liu, Xiaoxi, Phelps, Mitch A., Mould, Diane R.
Publicado 2021

Population Pharmacokinetic Analysis of Bortezomib in Pediatric Leukemia Patients: Model‐Based Support for Body Surface Area‐Based Dosing Over the 2‐ to 16‐Year Age Range

por Hanley, Michael J., Mould, Diane R., Taylor, Timothy J., Gupta, Neeraj, Suryanarayan, Kaveri, Neuwirth, Rachel, Esseltine, Dixie‐Lee, Horton, Terzah M., Aplenc, Richard, Alonzo, Todd A., Lu, Xiaomin, Milton, Ashley, Venkatakrishnan, Karthik
Publicado 2017

Pharmacokinetic‐Pharmacodynamic Model of Neutropenia in Patients With Myeloma Receiving High‐Dose Melphalan for Autologous Stem Cell Transplant

por Cho, Yu Kyoung, Irby, Donald J., Li, Junan, Sborov, Douglas W., Mould, Diane R., Badawi, Mohamed, Dauki, Anees, Lamprecht, Misty, Rosko, Ashley E., Fernandez, Soledad, Hade, Erinn M., Hofmeister, Craig C., Poi, Ming, Phelps, Mitch A.
Publicado 2018