Response of Brain Metastases From PIK3CA-Mutant Breast Cancer to Alpelisib

por Batalini, Felipe, Moulder, Stacy L., Winer, Eric P., Rugo, Hope S., Lin, Nancy U., Wulf, Gerburg M.
Publicado 2020

Multiple gene aberrations and breast cancer: lessons from super-responders

por Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle
Publicado 2015

Challenges and perspective of drug repurposing strategies in early phase clinical trials

por Kato, Shumei, Moulder, Stacy L., Ueno, Naoto T., Wheler, Jennifer J., Meric-Bernstam, Funda, Kurzrock, Razelle, Janku, Filip
Publicado 2015

Impact of TP53 mutations in Triple Negative Breast Cancer

por Mitri, Zahi I., Abuhadra, Nour, Goodyear, Shaun M., Hobbs, Evthokia A., Kaempf, Andy, Thompson, Alastair M., Moulder, Stacy L.
Publicado 2022

Presence of both alterations in FGFR/FGF and PI3K/AKT/mTOR confer improved outcomes for patients with metastatic breast cancer treated with PI3K/AKT/mTOR inhibitors

por Wheler, Jennifer J., Atkins, Johnique T., Janku, Filip, Moulder, Stacy L., Stephens, Philip J., Yelensky, Roman, Valero, Vicente, Miller, Vincent, Kurzrock, Razelle, Meric-Bernstam, Funda
Publicado 2016

Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer

por Silva, Grace O., He, Xiaping, Parker, Joel S., Gatza, Michael L., Carey, Lisa A., Hou, Jack P., Moulder, Stacy L., Marcom, Paul K., Ma, Jian, Rosen, Jeffrey M., Perou, Charles M.
Publicado 2015

Comparison of three scoring methods using the FDA-approved 22C3 immunohistochemistry assay to evaluate PD-L1 expression in breast cancer and their association with clinicopathologi...

por Guo, Hua, Ding, Qingqing, Gong, Yun, Gilcrease, Michael Z., Zhao, Min, Zhao, Jun, Sui, Dawen, Wu, Yun, Chen, Hui, Liu, Hui, Zhang, Jinxia, Resetkova, Erika, Moulder, Stacy L., Wang, Wei-Lien, Huo, Lei
Publicado 2020

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway

por Wheler, Jennifer J., Moulder, Stacy L., Naing, Aung, Janku, Filip, Piha-Paul, Sarina A., Falchook, Gerald S., Zinner, Ralph, Tsimberidou, Apostolia M., Fu, Siqing, Hong, David S., Atkins, Johnique T., Yelensky, Roman, Stephens, Philip J., Kurzrock, Razelle
Publicado 2014

Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers

por Liu, Xuan, Ge, Zhongqi, Yang, Fei, Contreras, Alejandro, Lee, Sanghoon, White, Jason B., Lu, Yiling, Labrie, Marilyne, Arun, Banu K., Moulder, Stacy L., Mills, Gordon B., Piwnica-Worms, Helen, Litton, Jennifer K., Chang, Jeffrey T.
Publicado 2022

PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes

por Janku, Filip, Wheler, Jennifer J., Naing, Aung, Stepanek, Vanda M., Falchook, Gerald S., Fu, Siqing, Garrido-Laguna, Ignacio, Tsimberidou, Apostolia M., Piha-Paul, Sarina A., Moulder, Stacy L., Lee, J. Jack, Luthra, Rajyalakshmi, Hong, David S., Kurzrock, Razelle
Publicado 2012

High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

por Echeverria, Gloria V., Powell, Emily, Seth, Sahil, Ge, Zhongqi, Carugo, Alessandro, Bristow, Christopher, Peoples, Michael, Robinson, Frederick, Qiu, Huan, Shao, Jiansu, Jeter-Jones, Sabrina L., Zhang, Xiaomei, Ramamoorthy, Vandhana, Cai, Shirong, Wu, Wenhui, Draetta, Giulio, Moulder, Stacy L., Symmans, William F., Chang, Jeffrey T., Heffernan, Timothy P., Piwnica-Worms, Helen
Publicado 2018

A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis

por Powell, Emily, Shao, Jiansu, Picon, Hector M., Bristow, Christopher, Ge, Zhongqi, Peoples, Michael, Robinson, Frederick, Jeter-Jones, Sabrina L., Schlosberg, Christopher, Grzeskowiak, Caitlin L., Yang, Fei, Wu, Yun, Wistuba, Ignacio, Moulder, Stacy L., Symmans, William F., Scott, Kenneth L., Edwards, John R., Liang, Han, Heffernan, Timothy P., Piwnica-Worms, Helen
Publicado 2018

Clinical outcomes based on multigene profiling in metastatic breast cancer patients

por Basho, Reva K., de Melo Gagliato, Debora, Ueno, Naoto T., Wathoo, Chetna, Chen, Huiqin, Shariati, Maryam, Wei, Caimiao, Alvarez, Ricardo H., Moulder, Stacy L., Sahin, Aysegul A., Roy-Chowdhuri, Sinchita, Chavez-MacGregor, Mariana, Litton, Jennifer K., Valero, Vincent, Luthra, Raja, Zeng, Jia, Shaw, Kenna R., Mendelsohn, John, Mills, Gordon B., Tripathy, Debu, Meric-Bernstam, Funda
Publicado 2016

A phase Ib study of entinostat plus lapatinib with or without trastuzumab in patients with HER2-positive metastatic breast cancer that progressed during trastuzumab treatment

por Lim, Bora, Murthy, Rashmi K., Lee, Jangsoon, Jackson, Summer A., Iwase, Toshiaki, Davis, Darren W., Willey, Jie S., Wu, Jimin, Shen, Yu, Tripathy, Debu, Alvarez, Ricardo, Ibrahim, Nuhad K., Brewster, Abenaa M., Barcenas, Carlos H., Brown, Powel H., Giordano, Sharon H., Moulder, Stacy L., Booser, Daniel J., Moscow, Jeffrey A., Piekarz, Richard, Valero, Vicente, Ueno, Naoto T.
Publicado 2019

Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer

por Echeverria, Gloria V., Cai, Shirong, Tu, Yizheng, Shao, Jiansu, Powell, Emily, Redwood, Abena B., Jiang, Yan, McCoy, Aaron, Rinkenbaugh, Amanda L., Lau, Rosanna, Trevarton, Alexander J., Fu, Chunxiao, Gould, Rebekah, Ravenberg, Elizabeth E., Huo, Lei, Candelaria, Rosalind, Santiago, Lumarie, Adrada, Beatriz E., Lane, Deanna L., Rauch, Gaiane M., Yang, Wei T., White, Jason B., Chang, Jeffrey T., Moulder, Stacy L., Symmans, W. Fraser, Hilsenbeck, Susan G., Piwnica-Worms, Helen
Publicado 2023

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer

por Shah, Vrutant V., Duncan, Aundrietta D., Jiang, Shiming, Stratton, Sabrina A., Allton, Kendra L., Yam, Clinton, Jain, Abhinav, Krause, Patrick M., Lu, Yue, Cai, Shirong, Tu, Yizheng, Zhou, Xinhui, Zhang, Xiaomei, Jiang, Yan, Carroll, Christopher L., Kang, Zhijun, Liu, Bin, Shen, Jianjun, Gagea, Mihai, Manu, Sebastian M., Huo, Lei, Gilcrease, Michael, Powell, Reid T., Guo, Lei, Stephan, Clifford, Davies, Peter J., Parker-Thornburg, Jan, Lozano, Guillermina, Behringer, Richard R., Piwnica-Worms, Helen, Chang, Jeffrey T., Moulder, Stacy L., Barton, Michelle Craig
Publicado 2021

Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2(+) breast cancer in the adaptively randomized I-SPY2 trial

por Clark, Amy S., Yau, Christina, Wolf, Denise M., Petricoin, Emanuel F., van ‘t Veer, Laura J., Yee, Douglas, Moulder, Stacy L., Wallace, Anne M., Chien, A. Jo, Isaacs, Claudine, Boughey, Judy C., Albain, Kathy S., Kemmer, Kathleen, Haley, Barbara B., Han, Hyo S., Forero-Torres, Andres, Elias, Anthony, Lang, Julie E., Ellis, Erin D., Yung, Rachel, Tripathy, Debu, Nanda, Rita, Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Gallagher, Rosa I., Helsten, Teresa, Roesch, Erin, Ewing, Cheryl A., Alvarado, Michael, Crane, Erin P., Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Steeg, Katherine, Asare, Adam, Matthews, Jeffrey B., Berry, Scott, Sanil, Ashish, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Schwab, Richard B., Symmans, W. Fraser, Hylton, Nola M., Berry, Donald A., Esserman, Laura J., DeMichele, Angela M.
Publicado 2021

Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer

por Yee, Douglas, Isaacs, Claudine, Wolf, Denise M., Yau, Christina, Haluska, Paul, Giridhar, Karthik V., Forero-Torres, Andres, Jo Chien, A., Wallace, Anne M., Pusztai, Lajos, Albain, Kathy S., Ellis, Erin D., Beckwith, Heather, Haley, Barbara B., Elias, Anthony D., Boughey, Judy C., Kemmer, Kathleen, Yung, Rachel L., Pohlmann, Paula R., Tripathy, Debu, Clark, Amy S., Han, Hyo S., Nanda, Rita, Khan, Qamar J., Edmiston, Kristen K., Petricoin, Emanuel F., Stringer-Reasor, Erica, Falkson, Carla I., Majure, Melanie, Mukhtar, Rita A., Helsten, Teresa L., Moulder, Stacy L., Robinson, Patricia A., Wulfkuhle, Julia D., Brown-Swigart, Lamorna, Buxton, Meredith, Clennell, Julia L., Paoloni, Melissa, Sanil, Ashish, Berry, Scott, Asare, Smita M., Wilson, Amy, Hirst, Gillian L., Singhrao, Ruby, Asare, Adam L., Matthews, Jeffrey B., Hylton, Nola M., DeMichele, Angela, Melisko, Michelle, Perlmutter, Jane, Rugo, Hope S., Fraser Symmans, W., van‘t Veer, Laura J., Berry, Donald A., Esserman, Laura J.
Publicado 2021