Novel HDAC/Tubulin Dual Inhibitor: Design, Synthesis and Docking Studies of α-Phthalimido-Chalcone Hybrids as Potential Anticancer Agents with Apoptosis-Inducing Activity

por Mourad, Ahmed A E, Mourad, Mai A E, Jones, Peter G
Publicado 2020

Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids

por Mourad, Ahmed A. E., Khodir, Ahmed E., Saber, Sameh, Mourad, Mai A. E.
Publicado 2021

Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals

por Aboubakr, Esam M., Ibrahim, Ahmed R. N., Ali, Fares E. M., Mourad, Ahmed A. E., Ahmad, Adel M., Hofni, Amal
Publicado 2022

New Pyrazole-Clubbed Pyrimidine or Pyrazoline Hybrids as Anti-Methicillin-Resistant Staphylococcus aureus Agents: Design, Synthesis, In Vitro and In Vivo Evaluation, and Molecular...

por Mansour, Basem, El-Sherbeny, Magda A., Al-Omary, Fatmah A. M., Saber, Sameh, Ramadan, Heba A., El-Baz, Ahmed M., Mourad, Ahmed A. E., Abdel-Aziz, Naglaa I.
Publicado 2023

Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2′,3′:4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apopto...

por Mourad, Mai A. E., Abo Elmaaty, Ayman, Zaki, Islam, Mourad, Ahmed A. E., Hofni, Amal, Khodir, Ahmed E., Aboubakr, Esam M., Elkamhawy, Ahmed, Roh, Eun Joo, Al-Karmalawy, Ahmed A.
Publicado 2023

AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management...

por Abd El-Fattah, Eslam E., Saber, Sameh, Youssef, Mahmoud E., Eissa, Hanan, El-Ahwany, Eman, Amin, Noha A., Alqarni, Mohammed, Batiha, Gaber El-Saber, Obaidullah, Ahmad J., Kaddah, Mohamed M.Y., Ahmed Gaafar, Ahmed Gaafar, Mourad, Ahmed A.E., Mostafa-Hedeab, Gomaa, Abdelhamid, Amir Mohamed
Publicado 2022

A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction a...

por Saber, Sameh, Abd El-Fattah, Eslam E., Yahya, Galal, Gobba, Naglaa A., Maghmomeh, Abdalkareem Omar, Khodir, Ahmed E., Mourad, Ahmed A. E., Saad, Ahmed S., Mohammed, Hager G., Nouh, Nehal A., Shata, Ahmed, Amin, Noha A., Abou El-Rous, Magdy, Girgis, Samuel, El-Ahwany, Eman, Khalaf, Eman M., El-Kott, Attalla F., El-Baz, Ahmed M.
Publicado 2021