Uncoupling fork speed and origin activity to identify the primary cause of replicative stress phenotypes

por Rodriguez-Acebes, Sara, Mourón, Silvana, Méndez, Juan
Publicado 2018

Personalising and targeting antiangiogenic resistance: a complex and multifactorial approach

por Bueno, Maria J, Mouron, Silvana, Quintela-Fandino, Miguel
Publicado 2017

Monitoring vascular normalization: new opportunities for mitochondrial inhibitors in breast cancer

por Mouron, Silvana, Bueno, Maria J., Muñoz, Manuel, Quintela-Fandino, Miguel
Publicado 2021

Nintedanib plus letrozole in early breast cancer: a phase 0/I pharmacodynamic, pharmacokinetic, and safety clinical trial of combined FGFR1 and aromatase inhibition

por Quintela-Fandino, Miguel, Apala, Juan V., Malon, Diego, Mouron, Silvana, Hornedo, Javier, Gonzalez-Cortijo, Lucia, Colomer, Ramon, Guerra, Juan
Publicado 2019

[6]-Gingerol-Derived Semi-Synthetic Compound SSi6 Inhibits Tumor Growth and Metastatic Dissemination in Triple-Negative Breast Cancer Xenograft Models

por Luna-Dulcey, Liany, Almada da Silva, James, Jimenez-Renard, Veronica, Caleiras, Eduardo, Mouron, Silvana, Quintela-Fandino, Miguel, Cominetti, Marcia R.
Publicado 2021

Usefulness and real-world outcomes of next generation sequencing testing in patients with cancer: an observational study on the impact of selection based on clinical judgement

por Colomer, Ramon, Miranda, Jesús, Romero-Laorden, Nuria, Hornedo, Javier, González-Cortijo, Lucía, Mouron, Silvana, Bueno, Maria J., Mondéjar, Rebeca, Quintela-Fandino, Miguel
Publicado 2023

FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1

por Mouron, Silvana, Manso, Luis, Caleiras, Eduardo, Rodriguez-Peralto, Jose L., Rueda, Oscar M., Caldas, Carlos, Colomer, Ramon, Quintela-Fandino, Miguel, Bueno, Maria J.
Publicado 2021

Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells

por Hühn, Daniela, Martí‐Rodrigo, Pablo, Mouron, Silvana, Hansel, Catherine, Tschapalda, Kirsten, Porebski, Bartlomiej, Häggblad, Maria, Lidemalm, Louise, Quintela‐Fandino, Miguel, Carreras‐Puigvert, Jordi, Fernandez‐Capetillo, Oscar
Publicado 2021

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells

por García-Gómez, Sara, Reyes, Aurelio, Martínez-Jiménez, María I., Chocrón, E. Sandra, Mourón, Silvana, Terrados, Gloria, Powell, Christopher, Salido, Eduardo, Méndez, Juan, Holt, Ian J., Blanco, Luis
Publicado 2013

Monitoring vascular normalization induced by antiangiogenic treatment with 18F‐fluoromisonidazole‐PET

por Hernández-Agudo, Elena, Mondejar, Tamara, Soto-Montenegro, Maria Luisa, Megías, Diego, Mouron, Silvana, Sanchez, Jesus, Hidalgo, Manuel, Lopez-Casas, Pedro Pablo, Mulero, Francisca, Desco, Manuel, Quintela-Fandino, Miguel
Publicado 2015

Tumor P70S6K hyperactivation is inversely associated with tumor-infiltrating lymphocytes in triple-negative breast cancer

por Jimeno, Rebeca, Mouron, Silvana, Salgado, Roberto, Loi, Sherene, Pérez-Mies, Belén, Sánchez-Bayona, Rodrigo, Manso, Luis, Martínez, Mario, Garrido-García, Ana, Serrano-Pardo, Rosario, Colomer, Ramón, Quintela-Fandino, Miguel
Publicado 2022

Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance

por Manso, Luis, Mourón, Silvana, Tress, Michael, Gómez-López, Gonzalo, Morente, Manuel, Ciruelos, Eva, Rubio-Camarillo, Miriam, Rodriguez-Peralto, Jose Luis, Pujana, Miguel A., Pisano, David G., Quintela-Fandino, Miguel
Publicado 2016

p27(Kip1) V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor–positive breast cancer

por Mouron, Silvana, Bueno, Maria J, Muñoz, Manuel, Torres, Raul, Rodríguez, Sandra, Apala, Juan V, Silva, Jorge, Sánchez-Bayona, Rodrigo, Manso, Luis, Guerra, Juan, Rodriguez-Lajusticia, Laura, Malon, Diego, Malumbres, Marcos, Quintela-Fandino, Miguel
Publicado 2023

Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial

por Quintela-Fandino, Miguel, Holgado, Esther, Manso, Luis, Morales, Serafin, Bermejo, Begoña, Colomer, Ramon, Apala, Juan V., Blanco, Raquel, Muñoz, Manuel, Caleiras, Eduardo, Iranzo, Vega, Martinez, Mario, Dominguez, Orlando, Hornedo, Javier, Gonzalez-Cortijo, Lucia, Cortes, Javier, Gasol Cudos, Ariadna, Malon, Diego, Lopez-Alonso, Antonio, Moreno-Ortíz, María C., Mouron, Silvana, Mañes, Santos
Publicado 2020

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer

por Ciscar, Marina, Trinidad, Eva M, Perez‐Chacon, Gema, Alsaleem, Mansour, Jimenez, Maria, Jimenez‐Santos, Maria J, Perez‐Montoyo, Hector, Sanz‐Moreno, Adrian, Vethencourt, Andrea, Toss, Michael, Petit, Anna, Soler‐Monso, Maria T, Lopez, Victor, Gomez‐Miragaya, Jorge, Gomez‐Aleza, Clara, Dobrolecki, Lacey E, Lewis, Michael T, Bruna, Alejandra, Mouron, Silvana, Quintela‐Fandino, Miguel, Al‐Shahrour, Fatima, Martinez‐Aranda, Antonio, Sierra, Angels, Green, Andrew R, Rakha, Emad, Gonzalez‐Suarez, Eva
Publicado 2023

Critically short telomeres and toxicity of chemotherapy in early breast cancer

por Quintela-Fandino, Miguel, Soberon, Nora, Lluch, Ana, Manso, Luis, Calvo, Isabel, Cortes, Javier, Moreno-Antón, Fernando, Gil-Gil, Miguel, Martinez-Jánez, Noelia, Gonzalez-Martin, Antonio, Adrover, Encarna, de Andres, Raquel, Viñas, Gemma, Llombart-Cussac, Antonio, Alba, Emilio, Mouron, Silvana, Guerra, Juan, Bermejo, Begoña, Zamora, Esther, García-Saenz, Jose Angel, Simon, Sonia Pernas, Carrasco, Eva, Escudero, María José, Campo, Ruth, Colomer, Ramón, Blasco, Maria A
Publicado 2017

In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer

por Zagorac, Ivana, Fernandez-Gaitero, Sara, Penning, Renske, Post, Harm, Bueno, Maria J., Mouron, Silvana, Manso, Luis, Morente, Manuel M., Alonso, Soledad, Serra, Violeta, Muñoz, Javier, Gómez-López, Gonzalo, Lopez-Acosta, Jose Francisco, Jimenez-Renard, Veronica, Gris-Oliver, Albert, Al-Shahrour, Fatima, Piñeiro-Yañez, Elena, Montoya-Suarez, Jose Luis, Apala, Juan V., Moreno-Torres, Amalia, Colomer, Ramon, Dopazo, Ana, Heck, Albert J. R., Altelaar, Maarten, Quintela-Fandino, Miguel
Publicado 2018

A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

por Zhu, Lucía, Retana, Diana, García‐Gómez, Pedro, Álvaro‐Espinosa, Laura, Priego, Neibla, Masmudi‐Martín, Mariam, Yebra, Natalia, Miarka, Lauritz, Hernández‐Encinas, Elena, Blanco‐Aparicio, Carmen, Martínez, Sonia, Sobrino, Cecilia, Ajenjo, Nuria, Artiga, Maria‐Jesus, Ortega‐Paino, Eva, Torres‐Ruiz, Raúl, Rodríguez‐Perales, Sandra, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, González‐León, Pedro, Jiménez‐Roldán, Luis, Moreno, Luis Miguel, Esteban, Olga, Pérez‐Núñez, Ángel, Hernández‐Laín, Aurelio, Toldos, Oscar, Ruano, Yolanda, Alcázar, Lucía, Blasco, Guillermo, Fernández‐Alén, José, Caleiras, Eduardo, Lafarga, Miguel, Megías, Diego, Graña‐Castro, Osvaldo, Nör, Carolina, Taylor, Michael D, Young, Leonie S, Varešlija, Damir, Cosgrove, Nicola, Couch, Fergus J, Cussó, Lorena, Desco, Manuel, Mouron, Silvana, Quintela‐Fandino, Miguel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel
Publicado 2022