Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies

por Scheepers, Cathrine, Kgagudi, Prudence, Mzindle, Nonkululeko, Gray, Elin S., Moyo-Gwete, Thandeka, Lambson, Bronwen E., Oosthuysen, Brent, Mabvakure, Batsirai, Garrett, Nigel J., Abdool Karim, Salim S., Morris, Lynn, Moore, Penny L.
Publicado 2022

Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms

por Moyo-Gwete, Thandeka, Scheepers, Cathrine, Makhado, Zanele, Kgagudi, Prudence, Mzindle, Nonkululeko B., Ziki, Rutendo, Madzorera, Sharon, Manamela, Nelia P., Ayres, Frances, Lambson, Bronwen E., Richardson, Simone I., Morris, Lynn, Moore, Penny L.
Publicado 2022

Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience

por Glatt, Tanya Nadia, Hilton, Caroline, Nyoni, Cynthia, Swarts, Avril, Swanevelder, Ronel, Cowley, James, Mmenu, Cordelia, Moyo-Gwete, Thandeka, Moore, Penny L., Kutama, Munzhedzi, Jaza, Jabulisile, Phayane, Itumeleng, Brits, Tinus, Koekemoer, Johan, Jentsch, Ute, Nelson, Derrick, van den Berg, Karin, Vermeulen, Marion
Publicado 2021

Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination

por Motsoeneng, Boitumelo M., Manamela, Nelia P., Kaldine, Haajira, Kgagudi, Prudence, Hermanus, Tandile, Ayres, Frances, Makhado, Zanele, Moyo-Gwete, Thandeka, van der Mescht, Mieke A., Abdullah, Fareed, Boswell, Michael T., Ueckermann, Veronica, Rossouw, Theresa M., Madhi, Shabir A., Moore, Penny L., Richardson, Simone I.
Publicado 2023

Therapeutic effect of CT-P59 against SARS-CoV-2 South African variant

por Ryu, Dong-Kyun, Song, Rina, Kim, Minsoo, Kim, Young-Il, Kim, Cheolmin, Kim, Jong-In, Kwon, Ki-Sung, Tijsma, Aloys SL., Nuijten, Patricia M., van Baalen, Carel A., Hermanus, Tandile, Kgagudi, Prudence, Moyo-Gwete, Thandeka, Moore, Penny L., Choi, Young Ki, Lee, Soo-Young
Publicado 2021

SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021

por Mandolo, Jonathan, Msefula, Jacquline, Henrion, Marc Y. R., Brown, Comfort, Moyo, Brewster, Samon, Aubrey, Moyo-Gwete, Thandeka, Makhado, Zanele, Ayres, Frances, Motlou, Thopisang, Mzindle, Nonkululeko, Kalata, Newton, Muula, Adamson S., Kwatra, Gaurav, Nsamala, Natasha, Likaka, Andrew, Mfune, Thom, Moore, Penny L., Mbaya, Bridon, French, Neil, Heyderman, Robert S., Swarthout, Todd, Jambo, Kondwani C.
Publicado 2021

Shared N417-Dependent Epitope on the SARS-CoV-2 Omicron, Beta, and Delta Plus Variants

por Moyo-Gwete, Thandeka, Madzivhandila, Mashudu, Mkhize, Nonhlanhla N., Kgagudi, Prudence, Ayres, Frances, Lambson, Bronwen E., Manamela, Nelia P., Richardson, Simone I., Makhado, Zanele, van der Mescht, Mieke A., de Beer, Zelda, de Villiers, Talita Roma, Burgers, Wendy A., Ntusi, Ntobeko A. B., Rossouw, Theresa, Ueckermann, Veronica, Boswell, Michael T., Moore, Penny L.
Publicado 2022

AstraZeneca COVID-19 vaccine induces robust broadly cross-reactive antibody responses in Malawian adults previously infected with SARS-CoV-2

por Chibwana, Marah G., Moyo-Gwete, Thandeka, Kwatra, Gaurav, Mandolo, Jonathan, Hermanaus, Tandile, Motlou, Thopisang, Mzindle, Nonkululeko, Ayres, Frances, Chaponda, Mphatso, Tembo, Godwin, Mwenechanya, Percy, Mitole, Ndaona, Jassi, Chisomo, Kamng’ona, Raphael, Afran, Louise, Mzinza, David, Mwandumba, Henry C., Gordon, Stephen B., Jere, Khuzwayo, Madhi, Shabir, Moore, Penny L., Heyderman, Robert S., Jambo, Kondwani C.
Publicado 2022

Distinct T cell functional profiles in SARS-CoV-2 seropositive and seronegative children associated with endemic human coronavirus cross-reactivity

por Benede, Ntombi S. B., Tincho, Marius B., Walters, Avril, Subbiah, Vennesa, Ngomti, Amkele, Baguma, Richard, Butters, Claire, Mennen, Mathilda, Skelem, Sango, Adriaanse, Marguerite, van Graan, Strauss, Balla, Sashkia R., Moyo-Gwete, Thandeka, Moore, Penny L., Botha, Maresa, Workman, Lesley, Zar, Heather J., Ntusi, Ntobeko A. B., Zühlke, Liesl, Webb, Kate, Riou, Catherine, Burgers, Wendy A., Keeton, Roanne S.
Publicado 2023

Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection

por Moyo-Gwete, Thandeka, Richardson, Simone I., Keeton, Roanne, Hermanus, Tandile, Spencer, Holly, Manamela, Nelia P., Ayres, Frances, Makhado, Zanele, Motlou, Thopisang, Tincho, Marius B., Benede, Ntombi, Ngomti, Amkele, Baguma, Richard, Chauke, Masego V., Mennen, Mathilda, Adriaanse, Marguerite, Skelem, Sango, Goga, Ameena, Garrett, Nigel, Bekker, Linda-Gail, Gray, Glenda, Ntusi, Ntobeko A.B., Riou, Catherine, Burgers, Wendy A., Moore, Penny L.
Publicado 2023

Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells

por Krause, Robert G. E., Moyo-Gwete, Thandeka, Richardson, Simone I., Makhado, Zanele, Manamela, Nelia P., Hermanus, Tandile, Mkhize, Nonhlanhla N., Keeton, Roanne, Benede, Ntombi, Mennen, Mathilda, Skelem, Sango, Karim, Farina, Khan, Khadija, Riou, Catherine, Ntusi, Ntobeko A. B., Goga, Ameena, Gray, Glenda, Hanekom, Willem, Garrett, Nigel, Bekker, Linda-Gail, Groll, Andreas, Sigal, Alex, Moore, Penny L., Burgers, Wendy A., Leslie, Alasdair
Publicado 2023

Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection

por Moyo-Gwete, Thandeka, Richardson, Simone I., Keeton, Roanne, Hermanus, Tandile, Spencer, Holly, Manamela, Nelia P., Ayres, Frances, Makhado, Zanele, Motlou, Thopisang, Tincho, Marius B., Benede, Ntombi, Ngomti, Amkele, Baguma, Richard, Chauke, Masego V., Mennen, Mathilda, Adriaanse, Marguerite, Skelem, Sango, Goga, Ameena, Garrett, Nigel, Bekker, Linda-Gail, Gray, Glenda, Ntusi, Ntobeko A. B., Riou, Catherine, Burgers, Wendy A., Moore, Penny L.
Publicado 2023

SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies

por Moyo-Gwete, Thandeka, Madzivhandila, Mashudu, Makhado, Zanele, Ayres, Frances, Mhlanga, Donald, Oosthuysen, Brent, Lambson, Bronwen E., Kgagudi, Prudence, Tegally, Houriiyah, Iranzadeh, Arash, Doolabh, Deelan, Tyers, Lynn, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, Marais, Gert, Wibmer, Constantinos Kurt, Bhiman, Jinal N, Ueckermann, Veronica, Rossouw, Theresa, Boswell, Michael, de Oliveira, Tulio, Williamson, Carolyn, Burgers, Wendy A, Ntusi, Ntobeko, Morris, Lynn, Moore, Penny L
Publicado 2021

Cross-Reactive Neutralizing Antibody Responses Elicited by SARS-CoV-2 501Y.V2 (B.1.351)

por Moyo-Gwete, Thandeka, Madzivhandila, Mashudu, Makhado, Zanele, Ayres, Frances, Mhlanga, Donald, Oosthuysen, Brent, Lambson, Bronwen E., Kgagudi, Prudence, Tegally, Houriiyah, Iranzadeh, Arash, Doolabh, Deelan, Tyers, Lynn, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, Marais, Gert, Wibmer, Constantinos K., Bhiman, Jinal N., Ueckermann, Veronica, Rossouw, Theresa, Boswell, Michael, de Oliveira, Tulio, Williamson, Carolyn, Burgers, Wendy A., Ntusi, Ntobeko, Morris, Lynn, Moore, Penny L.
Publicado 2021

Ad26.COV2.S breakthrough infections induce high titers of neutralizing antibodies against Omicron and other SARS-CoV-2 variants of concern

por Kitchin, Dale, Richardson, Simone I., van der Mescht, Mieke A., Motlou, Thopisang, Mzindle, Nonkululeko, Moyo-Gwete, Thandeka, Makhado, Zanele, Ayres, Frances, Manamela, Nelia P., Spencer, Holly, Lambson, Bronwen, Oosthuysen, Brent, Kaldine, Haajira, du Pisanie, Marizane, Mennen, Mathilda, Skelem, Sango, Williams, Noleen, Ntusi, Ntobeko A.B., Burgers, Wendy A., Gray, Glenda G., Bekker, Linda-Gail, Boswell, Michael T., Rossouw, Theresa M., Ueckermann, Veronica, Moore, Penny L.
Publicado 2022

SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated, individuals

por Richardson, Simone I., Madzorera, Vimbai Sharon, Spencer, Holly, Manamela, Nelia P., van der Mescht, Mieke A., Lambson, Bronwen E., Oosthuysen, Brent, Ayres, Frances, Makhado, Zanele, Moyo-Gwete, Thandeka, Mzindle, Nonkululeko, Motlou, Thopisang, Strydom, Amy, Mendes, Adriano, Tegally, Houriiyah, de Beer, Zelda, Roma de Villiers, Talita, Bodenstein, Annie, van den Berg, Gretha, Venter, Marietjie, de Oliviera, Tulio, Ueckermann, Veronica, Rossouw, Theresa M., Boswell, Michael T., Moore, Penny L.
Publicado 2022

Escape from recognition of SARS-CoV-2 Beta variant spike epitopes but overall preservation of T cell immunity

por Riou, Catherine, Keeton, Roanne, Moyo-Gwete, Thandeka, Hermanus, Tandile, Kgagudi, Prudence, Baguma, Richard, Valley-Omar, Ziyaad, Smith, Mikhail, Tegally, Houriiyah, Doolabh, Deelan, Iranzadeh, Arash, Tyers, Lynn, Mutavhatsindi, Hygon, Tincho, Marius B., Benede, Ntombi, Marais, Gert, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, du Bruyn, Elsa, Stek, Cari, de Oliveira, Tulio, Williamson, Carolyn, Moore, Penny L., Wilkinson, Robert J., Ntusi, Ntobeko A. B., Burgers, Wendy A.
Publicado 2022

SARS-CoV-2 evolved during advanced HIV disease immunosuppression has Beta-like escape of vaccine and Delta infection elicited immunity

por Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W., Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I., Karim, Salim Abdool, Hanekom, Willem, Van Voorhis, Wesley C., Ndung’u, Thumbi, Lessells, Richard J., Moore, Penny L., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, Sigal, Alex
Publicado 2021

SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

por Cele, Sandile, Karim, Farina, Lustig, Gila, San, James Emmanuel, Hermanus, Tandile, Tegally, Houriiyah, Snyman, Jumari, Moyo-Gwete, Thandeka, Wilkinson, Eduan, Bernstein, Mallory, Khan, Khadija, Hwa, Shi-Hsia, Tilles, Sasha W., Singh, Lavanya, Giandhari, Jennifer, Mthabela, Ntombifuthi, Mazibuko, Matilda, Ganga, Yashica, Gosnell, Bernadett I., Karim, Salim S. Abdool, Hanekom, Willem, Van Voorhis, Wesley C., Ndung’u, Thumbi, Lessells, Richard J., Moore, Penny L., Moosa, Mahomed-Yunus S., de Oliveira, Tulio, Sigal, Alex
Publicado 2022

Convalescent plasma in the treatment of moderate to severe COVID-19 pneumonia: a randomized controlled trial (PROTECT-Patient Trial)

por van den Berg, Karin, Glatt, Tanya Nadia, Vermeulen, Marion, Little, Francesca, Swanevelder, Ronel, Barrett, Claire, Court, Richard, Bremer, Marise, Nyoni, Cynthia, Swarts, Avril, Mmenu, Cordelia, Crede, Thomas, Kritzinger, Gerdien, Naude, Jonathan, Szymanski, Patryk, Cowley, James, Moyo-Gwete, Thandeka, Moore, Penny L., Black, John, Singh, Jaimendra, Bhiman, Jinal N., Baijnath, Prinita, Mody, Priyesh, Malherbe, Jacques, Potgieter, Samantha, van Vuuren, Cloete, Maasdorp, Shaun, Wilkinson, Robert J., Louw, Vernon J., Wasserman, Sean
Publicado 2022