Evolutionary divergence of Firre localization and expression

por Much, Christian, Smallegan, Michael J., Hwang, Taeyoung, Hanson, Skylar D., Dumbović, Gabrijela, Rinn, John L.
Publicado 2022

Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein

por Much, Christian, Auchynnikava, Tania, Pavlinic, Dinko, Buness, Andreas, Rappsilber, Juri, Benes, Vladimir, Allshire, Robin, O’Carroll, Dónal
Publicado 2016

Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci

por Comazzetto, Stefano, Di Giacomo, Monica, Rasmussen, Kasper Dindler, Much, Christian, Azzi, Chiara, Perlas, Emerald, Morgan, Marcos, O'Carroll, Dónal
Publicado 2014

The RNA m(6)A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

por Ivanova, Ivayla, Much, Christian, Di Giacomo, Monica, Azzi, Chiara, Morgan, Marcos, Moreira, Pedro N., Monahan, Jack, Carrieri, Claudia, Enright, Anton J., O’Carroll, Dónal
Publicado 2017

mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

por Morgan, Marcos, Much, Christian, DiGiacomo, Monica, Azzi, Chiara, Ivanova, Ivayla, Vitsios, Dimitrios M., Pistolic, Jelena, Collier, Paul, Moreira, Pedro, Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal
Publicado 2017

Terminal uridylyltransferases target RNA viruses as part of the innate immune system

por Le Pen, Jérémie, Jiang, Hongbing, Di Domenico, Tomás, Kneuss, Emma, Kosałka, Joanna, Leung, Christian, Morgan, Marcos, Much, Christian, Rudolph, Konrad L. M., Enright, Anton J., O’Carroll, Dónal, Wang, David, Miska, Eric A.
Publicado 2018

NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells

por Codino, Azzurra, Turowski, Tomasz, van de Lagemaat, Louie N., Ivanova, Ivayla, Tavosanis, Andrea, Much, Christian, Auchynnikava, Tania, Vasiliauskaitė, Lina, Morgan, Marcos, Rappsilber, Juri, Allshire, Robin C., Kranc, Kamil R., Tollervey, David, O'Carroll, Dónal
Publicado 2021

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

por Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal
Publicado 2019

Structural and functional basis of mammalian microRNA biogenesis by Dicer

por Zapletal, David, Taborska, Eliska, Pasulka, Josef, Malik, Radek, Kubicek, Karel, Zanova, Martina, Much, Christian, Sebesta, Marek, Buccheri, Valeria, Horvat, Filip, Jenickova, Irena, Prochazkova, Michaela, Prochazka, Jan, Pinkas, Matyas, Novacek, Jiri, Joseph, Diego F., Sedlacek, Radislav, Bernecky, Carrie, O’Carroll, Dónal, Stefl, Richard, Svoboda, Petr
Publicado 2022

T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation

por Landshammer, Alexandro, Bolondi, Adriano, Kretzmer, Helene, Much, Christian, Buschow, René, Rose, Alina, Wu, Hua-Jun, Mackowiak, Sebastian D, Braendl, Bjoern, Giesselmann, Pay, Tornisiello, Rosaria, Parsi, Krishna Mohan, Huey, Jack, Mielke, Thorsten, Meierhofer, David, Maehr, René, Hnisz, Denes, Michor, Franziska, Rinn, John L, Meissner, Alexander
Publicado 2023

The mRNA m(6)A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function

por Mapperley, Christopher, van de Lagemaat, Louie N., Lawson, Hannah, Tavosanis, Andrea, Paris, Jasmin, Campos, Joana, Wotherspoon, David, Durko, Jozef, Sarapuu, Annika, Choe, Junho, Ivanova, Ivayla, Krause, Daniela S., von Kriegsheim, Alex, Much, Christian, Morgan, Marcos, Gregory, Richard I., Mead, Adam J., O’Carroll, Dónal, Kranc, Kamil R.
Publicado 2020

The Tug1 lncRNA locus is essential for male fertility

por Lewandowski, Jordan P., Dumbović, Gabrijela, Watson, Audrey R., Hwang, Taeyoung, Jacobs-Palmer, Emily, Chang, Nydia, Much, Christian, Turner, Kyle M., Kirby, Christopher, Rubinstein, Nimrod D., Groff, Abigail F., Liapis, Steve C., Gerhardinger, Chiara, Bester, Assaf, Pandolfi, Pier Paolo, Clohessy, John G., Hoekstra, Hopi E., Sauvageau, Martin, Rinn, John L.
Publicado 2020

Targeting the RNA m(6)A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia

por Paris, Jasmin, Morgan, Marcos, Campos, Joana, Spencer, Gary J., Shmakova, Alena, Ivanova, Ivayla, Mapperley, Christopher, Lawson, Hannah, Wotherspoon, David A., Sepulveda, Catarina, Vukovic, Milica, Allen, Lewis, Sarapuu, Annika, Tavosanis, Andrea, Guitart, Amelie V., Villacreces, Arnaud, Much, Christian, Choe, Junho, Azar, Ali, van de Lagemaat, Louie N., Vernimmen, Douglas, Nehme, Ali, Mazurier, Frederic, Somervaille, Tim C.P., Gregory, Richard I., O’Carroll, Dónal, Kranc, Kamil R.
Publicado 2019