Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data

por Forster, Michael, Szymczak, Silke, Ellinghaus, David, Hemmrich, Georg, Rühlemann, Malte, Kraemer, Lars, Mucha, Sören, Wienbrandt, Lars, Stanulla, Martin, Franke, Andre
Publicado 2015

The Macrophage Migration Inhibitory Factor (MIF) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery

por Averdunk, Luisa, Bernhagen, Jürgen, Fehnle, Karl, Surowy, Harald, Lüdecke, Hermann-Josef, Mucha, Sören, Meybohm, Patrick, Wieczorek, Dagmar, Leng, Lin, Marx, Gernot, Leaf, David E., Zarbock, Alexander, Zacharowski, Kai, Bucala, Richard, Stoppe, Christian
Publicado 2020

The interleukin-11 receptor variant p.W307R results in craniosynostosis in humans

por Ahmad, Ilyas, Lokau, Juliane, Kespohl, Birte, Malik, Naveed Altaf, Baig, Shahid Mahmood, Hartig, Roland, Behme, Daniel, Schwab, Roland, Altmüller, Janine, Jameel, Muhammad, Mucha, Sören, Thiele, Holger, Tariq, Muhammad, Nürnberg, Peter, Erdmann, Jeanette, Garbers, Christoph
Publicado 2023

Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap

por Schwarz, Emanuel, Alnæs, Dag, Andreassen, Ole A., Cao, Han, Chen, Junfang, Degenhardt, Franziska, Doncevic, Daria, Dwyer, Dominic, Eils, Roland, Erdmann, Jeanette, Herrmann, Carl, Hofmann-Apitius, Martin, Kaufmann, Tobias, Koutsouleris, Nikolaos, Kodamullil, Alpha T., Khuntia, Adyasha, Mucha, Sören, Nöthen, Markus M., Paul, Riya, Pedersen, Mads L., Quintero, Andres, Schunkert, Heribert, Sharma, Ashwini, Tost, Heike, Westlye, Lars T., Zhang, Youcheng, Meyer-Lindenberg, Andreas
Publicado 2020

Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2

por Visschedijk, Marijn C., Alberts, Rudi, Mucha, Soren, Deelen, Patrick, de Jong, Dirk J., Pierik, Marieke, Spekhorst, Lieke M., Imhann, Floris, van der Meulen-de Jong, Andrea E., van der Woude, C. Janneke, van Bodegraven, Adriaan A., Oldenburg, Bas, Löwenberg, Mark, Dijkstra, Gerard, Ellinghaus, David, Schreiber, Stefan, Wijmenga, Cisca, Rivas, Manuel A., Franke, Andre, van Diemen, Cleo C., Weersma, Rinse K.
Publicado 2016

Psoriasis and cardiometabolic traits: modest association but distinct genetic architectures

por Koch, Manja, Baurecht, Hansjörg, Ried, Janina S., Rodriguez, Elke, Schlesinger, Sabrina, Volks, Natalie, Gieger, Christian, Rückert, Ina-Maria, Heinrich, Luise, Willenborg, Christina, Smith, Catherine, Peters, Annette, Thorand, Barbara, Koenig, Wolfgang, Lamina, Claudia, Jansen, Henning, Kronenberg, Florian, Seissler, Jochen, Thiery, Joachim, Rathmann, Wolfgang, Schunkert, Heribert, Erdmann, Jeanette, Barker, Jonathan, Nair, Rajan P, Tsoi, Lam C, Elder, James T, Mrowietz, Ulrich, Weichenthal, Michael, Mucha, Sören, Schreiber, Stefan, Franke, Andre, Schmitt, Jochen, Lieb, Wolfgang, Weidinger, Stephan
Publicado 2015

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

por Tsoi, Lam C., Stuart, Philip E., Tian, Chao, Gudjonsson, Johann E., Das, Sayantan, Zawistowski, Matthew, Ellinghaus, Eva, Barker, Jonathan N., Chandran, Vinod, Dand, Nick, Duffin, Kristina Callis, Enerbäck, Charlotta, Esko, Tõnu, Franke, Andre, Gladman, Dafna D., Hoffmann, Per, Kingo, Külli, Kõks, Sulev, Krueger, Gerald G., Lim, Henry W., Metspalu, Andres, Mrowietz, Ulrich, Mucha, Sören, Rahman, Proton, Reis, Andre, Tejasvi, Trilokraj, Trembath, Richard, Voorhees, John J., Weidinger, Stephan, Weichenthal, Michael, Wen, Xiaoquan, Eriksson, Nicholas, Kang, Hyun M., Hinds, David A., Nair, Rajan P., Abecasis, Gonçalo R., Elder, James T
Publicado 2017

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

por Yin, Xianyong, Low, Hui Qi, Wang, Ling, Li, Yonghong, Ellinghaus, Eva, Han, Jiali, Estivill, Xavier, Sun, Liangdan, Zuo, Xianbo, Shen, Changbing, Zhu, Caihong, Zhang, Anping, Sanchez, Fabio, Padyukov, Leonid, Catanese, Joseph J., Krueger, Gerald G., Duffin, Kristina Callis, Mucha, Sören, Weichenthal, Michael, Weidinger, Stephan, Lieb, Wolfgang, Foo, Jia Nee, Li, Yi, Sim, Karseng, Liany, Herty, Irwan, Ishak, Teo, Yikying, Theng, Colin T. S., Gupta, Rashmi, Bowcock, Anne, De Jager, Philip L., Qureshi, Abrar A., de Bakker, Paul I. W., Seielstad, Mark, Liao, Wilson, Ståhle, Mona, Franke, Andre, Zhang, Xuejun, Liu, Jianjun
Publicado 2015

Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease

por Shadrin, Alexey A., Mucha, Sören, Ellinghaus, David, Makarious, Mary B., Blauwendraat, Cornelis, Sreelatha, Ashwin A.K., Heras-Garvin, Antonio, Ding, Jinhui, Hammer, Monia, Foubert-Samier, Alexandra, Meissner, Wassilios G., Rascol, Olivier, Traon, Anne Pavy-Le, Frei, Oleksandr, O’Connell, Kevin S., Bahrami, Shahram, Schreiber, Stefan, Lieb, Wolfgang, Müller-Nurasyid, Martina, Schminke, Ulf, Homuth, Georg, Schmidt, Carsten O., Nöthen, Markus M., Hoffmann, Per, Gieger, Christian, Wenning, Gregor, Gibbs, J. Raphael, Franke, Andre, Hardy, John, Stefanova, Nadia, Gasser, Thomas, Singleton, Andrew, Houlden, Henry, Scholz, Sonja W., Andreassen, Ole A., Sharma, Manu
Publicado 2021

Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

por Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H., Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J.
Publicado 2016

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

por Dand, Nick, Mucha, Sören, Tsoi, Lam C, Mahil, Satveer K, Stuart, Philip E, Arnold, Andreas, Baurecht, Hansjörg, Burden, A David, Callis Duffin, Kristina, Chandran, Vinod, Curtis, Charles J, Das, Sayantan, Ellinghaus, David, Ellinghaus, Eva, Enerback, Charlotta, Esko, Tõnu, Gladman, Dafna D, Griffiths, Christopher E M, Gudjonsson, Johann E, Hoffman, Per, Homuth, Georg, Hüffmeier, Ulrike, Krueger, Gerald G, Laudes, Matthias, Lee, Sang Hyuck, Lieb, Wolfgang, Lim, Henry W, Löhr, Sabine, Mrowietz, Ulrich, Müller-Nurayid, Martina, Nöthen, Markus, Peters, Annette, Rahman, Proton, Reis, André, Reynolds, Nick J, Rodriguez, Elke, Schmidt, Carsten O, Spain, Sarah L, Strauch, Konstantin, Tejasvi, Trilokraj, Voorhees, John J, Warren, Richard B, Weichenthal, Michael, Weidinger, Stephan, Zawistowski, Matthew, Nair, Rajan P, Capon, Francesca, Smith, Catherine H, Trembath, Richard C, Abecasis, Goncalo R, Elder, James T, Franke, Andre, Simpson, Michael A, Barker, Jonathan N
Publicado 2017

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease

por Ji, Sun-Gou, Juran, Brian D, Mucha, Sören, Folseraas, Trine, Jostins, Luke, Melum, Espen, Kumasaka, Natsuhiko, Atkinson, Elizabeth J, Schlicht, Erik M, Liu, Jimmy Z, Shah, Tejas, Gutierrez-Achury, Javier, Boberg, Kirsten M, Bergquist, Annika, Vermeire, Severine, Eksteen, Bertus, Durie, Peter R, Farkkila, Martti, Müller, Tobias, Schramm, Christoph, Sterneck, Martina, Weismüller, Tobias J, Gotthardt, Daniel N, Ellinghaus, David, Braun, Felix, Teufel, Andreas, Laudes, Mattias, Lieb, Wolfgang, Jacobs, Gunnar, Beuers, Ulrich, Weersma, Rinse K, Wijmenga, Cisca, Marschall, Hanns-Ulrich, Milkiewicz, Piotr, Pares, Albert, Kontula, Kimmo, Chazouillères, Olivier, Invernizzi, Pietro, Goode, Elizabeth, Spiess, Kelly, Moore, Carmel, Sambrook, Jennifer, Ouwehand, Willem H, Roberts, David J, Danesh, John, Floreani, Annarosa, Gulamhusein, Aliya F, Eaton, John E, Schreiber, Stefan, Coltescu, Catalina, Bowlus, Christopher L, Luketic, Velimir A, Odin, Joseph A, Chopra, Kapil B, Kowdley, Kris V, Chalasani, Naga, Manns, Michael P, Srivastava, Brijesh, Mells, George, Sandford, Richard N, Alexander, Graeme, Gaffney, Daniel J, Chapman, Roger W, Hirschfield, Gideon M, de Andrade, Mariza, Rushbrook, Simon M, Franke, Andre, Karlsen, Tom H, Lazaridis, Konstantinos N, Anderson, Carl A
Publicado 2016

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

por Rivas, Manuel A., Graham, Daniel, Sulem, Patrick, Stevens, Christine, Desch, A. Nicole, Goyette, Philippe, Gudbjartsson, Daniel, Jonsdottir, Ingileif, Thorsteinsdottir, Unnur, Degenhardt, Frauke, Mucha, Sören, Kurki, Mitja I., Li, Dalin, D'Amato, Mauro, Annese, Vito, Vermeire, Severine, Weersma, Rinse K., Halfvarson, Jonas, Paavola-Sakki, Paulina, Lappalainen, Maarit, Lek, Monkol, Cummings, Beryl, Tukiainen, Taru, Haritunians, Talin, Halme, Leena, Koskinen, Lotta L. E., Ananthakrishnan, Ashwin N., Luo, Yang, Heap, Graham A., Visschedijk, Marijn C., MacArthur, Daniel G., Neale, Benjamin M., Ahmad, Tariq, Anderson, Carl A., Brant, Steven R., Duerr, Richard H., Silverberg, Mark S., Cho, Judy H, Palotie, Aarno, Saavalainen, Päivi, Kontula, Kimmo, Färkkilä, Martti, McGovern, Dermot P. B., Franke, Andre, Stefansson, Kari, Rioux, John D., Xavier, Ramnik J., Daly, Mark J., Barrett, J., de Lane, K., Edwards, C., Hart, A., Hawkey, C., Jostins, L., Kennedy, N., Lamb, C., Lee, J., Lees, C., Mansfield, J., Mathew, C., Mowatt, C., Newman, B., Nimmo, E., Parkes, M., Pollard, M., Prescott, N., Randall, J., Rice, D., Satsangi, J., Simmons, A., Tremelling, M., Uhlig, H., Wilson, D., Abraham, C., Achkar, J. P., Bitton, A., Boucher, G., Croitoru, K., Fleshner, P., Glas, J., Kugathasan, S., Limbergen, J. V., Milgrom, R., Proctor, D., Regueiro, M., Schumm, P. L., Sharma, Y., Stempak, J. M., Targan, S. R., Wang, M. H.
Publicado 2016

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

por Aragam, Krishna G., Jiang, Tao, Goel, Anuj, Kanoni, Stavroula, Wolford, Brooke N., Atri, Deepak S., Weeks, Elle M., Wang, Minxian, Hindy, George, Zhou, Wei, Grace, Christopher, Roselli, Carolina, Marston, Nicholas A., Kamanu, Frederick K., Surakka, Ida, Venegas, Loreto Muñoz, Sherliker, Paul, Koyama, Satoshi, Ishigaki, Kazuyoshi, Åsvold, Bjørn O., Brown, Michael R., Brumpton, Ben, de Vries, Paul S., Giannakopoulou, Olga, Giardoglou, Panagiota, Gudbjartsson, Daniel F., Güldener, Ulrich, Haider, Syed M. Ijlal, Helgadottir, Anna, Ibrahim, Maysson, Kastrati, Adnan, Kessler, Thorsten, Kyriakou, Theodosios, Konopka, Tomasz, Li, Ling, Ma, Lijiang, Meitinger, Thomas, Mucha, Sören, Munz, Matthias, Murgia, Federico, Nielsen, Jonas B., Nöthen, Markus M., Pang, Shichao, Reinberger, Tobias, Schnitzler, Gavin, Smedley, Damian, Thorleifsson, Gudmar, von Scheidt, Moritz, Ulirsch, Jacob C., Arnar, David O., Burtt, Noël P., Costanzo, Maria C., Flannick, Jason, Ito, Kaoru, Jang, Dong-Keun, Kamatani, Yoichiro, Khera, Amit V., Komuro, Issei, Kullo, Iftikhar J., Lotta, Luca A., Nelson, Christopher P., Roberts, Robert, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Webb, Thomas R., Baras, Aris, Björkegren, Johan L. M., Boerwinkle, Eric, Dedoussis, George, Holm, Hilma, Hveem, Kristian, Melander, Olle, Morrison, Alanna C., Orho-Melander, Marju, Rallidis, Loukianos S., Ruusalepp, Arno, Sabatine, Marc S., Stefansson, Kari, Zalloua, Pierre, Ellinor, Patrick T., Farrall, Martin, Danesh, John, Ruff, Christian T., Finucane, Hilary K., Hopewell, Jemma C., Clarke, Robert, Gupta, Rajat M., Erdmann, Jeanette, Samani, Nilesh J., Schunkert, Heribert, Watkins, Hugh, Willer, Cristen J., Deloukas, Panos, Kathiresan, Sekar, Butterworth, Adam S.
Publicado 2022