The Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study

por Muehler, Andreas, Kohlhof, Hella, Groeppel, Manfred, Vitt, Daniel
Publicado 2019

Safety, Tolerability and Pharmacokinetics of Vidofludimus calcium (IMU-838) After Single and Multiple Ascending Oral Doses in Healthy Male Subjects

por Muehler, Andreas, Kohlhof, Hella, Groeppel, Manfred, Vitt, Daniel
Publicado 2020

Clinical relevance of intestinal barrier dysfunction in common gastrointestinal diseases

por Muehler, Andreas, Slizgi, Jason R, Kohlhof, Hella, Groeppel, Manfred, Peelen, Evelyn, Vitt, Daniel
Publicado 2020

A double‐blind, randomized, placebo‐controlled phase 2 trial evaluating the selective dihydroorotate dehydrogenase inhibitor vidofludimus calcium in relapsing‐remitting multiple sc...

por Fox, Robert J., Wiendl, Heinz, Wolf, Christian, De Stefano, Nicola, Sellner, Johann, Gryb, Viktoriia, Rejdak, Konrad, Bozhinov, Plamen Stoyanov, Tomakh, Nataliya, Skrypchenko, Iryna, Muehler, Andreas R.
Publicado 2022

Safety and Efficacy of Vidofludimus Calcium in Patients Hospitalized with COVID-19: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial

por Vehreschild, Maria J. G. T., Atanasov, Petar, Yurko, Kateryna, Oancea, Cristian, Popov, Georgi, Smesnoi, Valentina, Placinta, Gheorghe, Kohlhof, Hella, Vitt, Daniel, Peelen, Evelyn, Mihajlović, Jelena, Muehler, Andreas R.
Publicado 2022

Effects of rifampin, itraconazole and esomeprazole on the pharmacokinetics of alisertib, an investigational aurora a kinase inhibitor in patients with advanced malignancies

por Zhou, Xiaofei, Pant, Shubham, Nemunaitis, John, Craig Lockhart, A., Falchook, Gerald, Bauer, Todd M., Patel, Manish, Sarantopoulos, John, Bargfrede, Michael, Muehler, Andreas, Rangachari, Lakshmi, Zhang, Bin, Venkatakrishnan, Karthik
Publicado 2017

IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro

por Hahn, Friedrich, Wangen, Christina, Häge, Sigrun, Peter, Antonia Sophia, Dobler, Gerhard, Hurst, Brett, Julander, Justin, Fuchs, Jonas, Ruzsics, Zsolt, Überla, Klaus, Jäck, Hans-Martin, Ptak, Roger, Muehler, Andreas, Gröppel, Manfred, Vitt, Daniel, Peelen, Evelyn, Kohlhof, Hella, Marschall, Manfred
Publicado 2020