Specification of BMP Signaling

por Nickel, Joachim, Mueller, Thomas D.
Publicado 2019

A Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor Promiscuity

por Harth, Stefan, Kotzsch, Alexander, Hu, Junli, Sebald, Walter, Mueller, Thomas D.
Publicado 2010

Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex

por Malinauskas, Tomas, Peer, Tina V., Bishop, Benjamin, Mueller, Thomas D., Siebold, Christian
Publicado 2020

Receptor oligomerization and beyond: a case study in bone morphogenetic proteins

por Heinecke, Kai, Seher, Axel, Schmitz, Werner, Mueller, Thomas D, Sebald, Walter, Nickel, Joachim
Publicado 2009

A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor

por Kraich, Michael, Klein, Markus, Patiño, Edwin, Harrer, Henning, Nickel, Joachim, Sebald, Walter, Mueller, Thomas D
Publicado 2006

A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor

por Weber, Dionys, Kotzsch, Alexander, Nickel, Joachim, Harth, Stefan, Seher, Axel, Mueller, Uwe, Sebald, Walter, Mueller, Thomas D
Publicado 2007

Gene expression profiling of connective tissue growth factor (CTGF) stimulated primary human tenon fibroblasts reveals an inflammatory and wound healing response in vitro

por Seher, Axel, Nickel, Joachim, Mueller, Thomas D., Kneitz, Susanne, Gebhardt, Susanne, ter Vehn, Tobias Meyer, Schlunck, Guenther, Sebald, Walter
Publicado 2011

Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition

por Boschert, Verena, van Dinther, Maarten, Weidauer, Stella, van Pee, Katharina, Muth, Eva-Maria, ten Dijke, Peter, Mueller, Thomas D.
Publicado 2013

Correction: Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-Knot for Wnt-Signaling Inhibition

por Boschert, Verena, van Dinther, Maarten, Weidauer, Stella, van Pee, Katharina, Muth, Eva-Maria, ten Dijke, Peter, Mueller, Thomas D.
Publicado 2014

A hypomorphic BMPR1B mutation causes du Pan acromesomelic dysplasia

por Stange, Katja, Désir, Julie, Kakar, Naseebullah, Mueller, Thomas D., Budde, Birgit S., Gordon, Christopher T., Horn, Denise, Seemann, Petra, Borck, Guntram
Publicado 2015

Design of Glycoengineered IL-4 Antagonists Employing Chemical and Biosynthetic Glycosylation

por Thomas, Sarah, Fiebig, Juliane E., Kuhn, Eva-Maria, Mayer, Dominik S., Filbeck, Sebastian, Schmitz, Werner, Krischke, Markus, Gropp, Roswitha, Mueller, Thomas D.
Publicado 2023

Identification of a Novel TGF-β-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-β-Receptor-3 (TGFR-3)

por Diestel, Uschi, Resch, Marcus, Meinhardt, Kathrin, Weiler, Sigrid, Hellmann, Tina V., Mueller, Thomas D., Nickel, Joachim, Eichler, Jutta, Muller, Yves A.
Publicado 2013

NOD-scid IL2R γ(null) mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways

por Zadeh-Khorasani, Maryam, Nolte, Thomas, Mueller, Thomas D, Pechlivanis, Markos, Rueff, Franziska, Wollenberg, Andreas, Fricker, Gert, Wolf, Eckhard, Siebeck, Matthias, Gropp, Roswitha
Publicado 2013

GDF-5 can act as a context-dependent BMP-2 antagonist

por Klammert, Uwe, Mueller, Thomas D., Hellmann, Tina V., Wuerzler, Kristian K., Kotzsch, Alexander, Schliermann, Anna, Schmitz, Werner, Kuebler, Alexander C., Sebald, Walter, Nickel, Joachim
Publicado 2015

The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed

por Fiebig, Juliane E., Weidauer, Stella E., Qiu, Li-Yan, Bauer, Markus, Schmieder, Peter, Beerbaum, Monika, Zhang, Jin-Li, Oschkinat, Hartmut, Sebald, Walter, Mueller, Thomas D.
Publicado 2013

An Activating Deletion Variant in the Submembrane Region of Natriuretic Peptide Receptor-B Causes Tall Stature

por Lauffer, Peter, Miranda-Laferte, Erick, van Duyvenvoorde, Hermine A, van Haeringen, Arie, Werner, Franziska, Boudin, Eveline, Schmidt, Hannes, Mueller, Thomas D, Kuhn, Michaela, van der Kaay, Daniëlle C M
Publicado 2020

Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development

por Billington, Charles J., Fiebig, Juliane E., Forsman, Cynthia L., Pham, Lan, Burbach, Nathan, Sun, Mu, Jaskoll, Tina, Mansky, Kim, Gopalakrishnan, Rajaram, O’Connor, Michael B., Mueller, Thomas D., Petryk, Anna
Publicado 2011

Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion

por Silva-Vilches, Cinthia, Pletinckx, Katrien, Lohnert, Miriam, Pavlovic, Vladimir, Ashour, Diyaaeldin, John, Vini, Vendelova, Emilia, Kneitz, Susanne, Zhou, Jie, Chen, Rena, Reinheckel, Thomas, Mueller, Thomas D., Bodem, Jochen, Lutz, Manfred B.
Publicado 2017

Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling

por van Dinther, Maarten, Zhang, Juan, Weidauer, Stella E., Boschert, Verena, Muth, Eva-Maria, Knappik, Achim, de Gorter, David J. J., van Kasteren, Puck B., Frisch, Christian, Mueller, Thomas D., ten Dijke, Peter
Publicado 2013

The Venus Flytrap Dionaea muscipula Counts Prey-Induced Action Potentials to Induce Sodium Uptake

por Böhm, Jennifer, Scherzer, Sönke, Krol, Elzbieta, Kreuzer, Ines, von Meyer, Katharina, Lorey, Christian, Mueller, Thomas D., Shabala, Lana, Monte, Isabel, Solano, Roberto, Al-Rasheid, Khaled A.S., Rennenberg, Heinz, Shabala, Sergey, Neher, Erwin, Hedrich, Rainer
Publicado 2016