ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1

por Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Smirnova, Irina, Ilyukha, Vladimir, Gautam, Avishekh, Degterev, Alexei, Poltorak, Alexander
Publicado 2021

ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF

por Muendlein, Hayley I., Connolly, Wilson M., Magri, Zoie, Jetton, David, Smirnova, Irina, Degterev, Alexei, Balachandran, Siddharth, Poltorak, Alexander
Publicado 2022

Constitutive Interferon Maintains GBP Expression Required for Release of Bacterial Components Upstream of Pyroptosis and Anti-DNA Responses

por Liu, Beiyun C., Sarhan, Joseph, Panda, Alexander, Muendlein, Hayley I., Ilyukha, Vladimir, Coers, Jörn, Yamamoto, Masahiro, Isberg, Ralph R., Poltorak, Alexander
Publicado 2018

Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis

por Sarhan, Joseph, Liu, Beiyun C., Muendlein, Hayley I., Weindel, Chi G., Smirnova, Irina, Tang, Amy Y., Ilyukha, Vladimir, Sorokin, Maxim, Buzdin, Anton, Fitzgerald, Katherine A., Poltorak, Alexander
Publicado 2018

Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

por Muendlein, Hayley I., Sarhan, Joseph, Liu, Beiyun C., Connolly, Wilson M., Schworer, Stephen A., Smirnova, Irina, Tang, Amy Y., Ilyukha, Vladimir, Pietruska, Jodie, Tahmasebi, Soroush, Sonenberg, Nahum, Degterev, Alexei, Poltorak, Alexander
Publicado 2020