Azacytidine (Vidaza®) in the treatment of myelodysplastic syndromes

por Raj, Kavita, Mufti, Ghulam J
Publicado 2006

Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes

por Giagounidis, Aristoteles, Mufti, Ghulam J., Fenaux, Pierre, Germing, Ulrich, List, Alan, MacBeth, Kyle J.
Publicado 2013

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

por Gaymes, Terry J, Shall, Sydney, Macpherson, Lee J, Twine, Natalie A, Lea, Nicholas C, Farzaneh, Farzin, Mufti, Ghulam J
Publicado 2021

RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis

por Alkhatabi, Heba A., McLornan, Donal P., Kulasekararaj, Austin G., Malik, Farooq, Seidl, Thomas, Darling, David, Gaken, Joop, Mufti, Ghulam J.
Publicado 2016

Practical recommendations on the use of lenalidomide in the management of myelodysplastic syndromes

por Giagounidis, Aristoteles, Fenaux, Pierre, Mufti, Ghulam J., Muus, Petra, Platzbecker, Uwe, Sanz, Guillermo, Cripe, Larry, Von Lilienfeld-Toal, Marie, Wells, Richard A.
Publicado 2008

SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

por Mian, Syed A., Rouault-Pierre, Kevin, Smith, Alexander E., Seidl, Thomas, Pizzitola, Irene, Kizilors, Aytug, Kulasekararaj, Austin G., Bonnet, Dominique, Mufti, Ghulam J.
Publicado 2015

Valuation of transfusion-free living in MDS: results of health utility interviews with patients

por Szende, Agota, Schaefer, Caroline, Goss, Thomas F, Heptinstall, Kathy, Knight, Robert, Lübbert, Michael, Deschler, Barbara, Fenaux, Pierre, Mufti, Ghulam J, Killick, Sally, List, Alan F
Publicado 2009

iNucs: inter-nucleosome interactions

por Oveisi, Mehrdad, Shukla, Manu, Seymen, Nogayhan, Ohno, Masae, Taniguchi, Yuichi, Nahata, Sunil, Loos, Remco, Mufti, Ghulam J, Allshire, Robin C, Dimitrov, Stefan, Karimi, Mohammad M
Publicado 2021

A Phase I trial of talazoparib in patients with advanced hematologic malignancies

por Gopal, Ajay K, Popat, Rakesh, Mattison, Ryan J, Menne, Tobias, Bloor, Adrian, Gaymes, Terry, Khwaja, Asim, Juckett, Mark, Chen, Ying, Cotter, Matthew J, Mufti, Ghulam J
Publicado 2021

A functional assay for microRNA target identification and validation

por Gäken, Joop, Mohamedali, Azim M., Jiang, Jie, Malik, Farooq, Stangl, Doris, Smith, Alexander E., Chronis, Constantinos, Kulasekararaj, Austin G., Thomas, N. Shaun B., Farzaneh, Farzin, Tavassoli, Mahvash, Mufti, Ghulam J.
Publicado 2012

Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1–risk myelodysplastic syndrome and thrombocytopenia

por Giagounidis, Aristoteles, Mufti, Ghulam J, Fenaux, Pierre, Sekeres, Mikkael A, Szer, Jeffrey, Platzbecker, Uwe, Kuendgen, Andrea, Gaidano, Gianluca, Wiktor-Jedrzejczak, Wieslaw, Hu, Kuolung, Woodard, Paul, Yang, Allen S, Kantarjian, Hagop M
Publicado 2014

Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome

por Kittang, Astrid Olsnes, Kordasti, Shahram, Sand, Kristoffer Evebø, Costantini, Benedetta, Kramer, Anne Marijn, Perezabellan, Pilar, Seidl, Thomas, Rye, Kristin Paulsen, Hagen, Karen Marie, Kulasekararaj, Austin, Bruserud, Øystein, Mufti, Ghulam J.
Publicado 2015

Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry

por Orr, Stephen J, Boutz, Daniel R, Wang, Rong, Chronis, Constantinos, Lea, Nicholas C, Thayaparan, Thivyan, Hamilton, Emma, Milewicz, Hanna, Blanc, Eric, Mufti, Ghulam J, Marcotte, Edward M, Thomas, N Shaun B
Publicado 2012

Mixed T Cell Chimerism After Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia Using an Alemtuzumab-Containing Regimen Is Shaped by Persistence of Recip...

por Grimaldi, Francesco, Potter, Victoria, Perez-Abellan, Pilar, Veluchamy, John P., Atif, Muhammad, Grain, Rosemary, Sen, Monica, Best, Steven, Lea, Nicholas, Rice, Carmel, Pagliuca, Antonio, Mufti, Ghulam J., Marsh, Judith C.W., Barber, Linda D.
Publicado 2017

Clinical and prognostic significance of small paroxysmal nocturnal hemoglobinuria clones in myelodysplastic syndrome and aplastic anemia

por Fattizzo, Bruno, Ireland, Robin, Dunlop, Alan, Yallop, Deborah, Kassam, Shireen, Large, Joanna, Gandhi, Shreyans, Muus, Petra, Manogaran, Charles, Sanchez, Katy, Consonni, Dario, Barcellini, Wilma, Mufti, Ghulam J., Marsh, Judith C. W., Kulasekararaj, Austin G.
Publicado 2021

Mutations in histone modulators are associated with prolonged survival during azacitidine therapy

por Tobiasson, Magnus, McLornan, Donal P., Karimi, Mohsen, Dimitriou, Marios, Jansson, Monika, Azenkoud, Asmaa Ben, Jädersten, Martin, Lindberg, Greger, Abdulkadir, Hani, Kulasekararaj, Austin, Ungerstedt, Johanna, Lennartsson, Andreas, Ekwall, Karl, Mufti, Ghulam J., Hellström-Lindberg, Eva
Publicado 2016

Neutrophil and platelet increases with luspatercept in lower-risk MDS: secondary endpoints from the MEDALIST trial

por Garcia-Manero, Guillermo, Mufti, Ghulam J., Fenaux, Pierre, Buckstein, Rena, Santini, Valeria, Díez-Campelo, María, Finelli, Carlo, Ilhan, Osman, Sekeres, Mikkael A., Zeidan, Amer M., Ito, Rodrigo, Zhang, Jennie, Rampersad, Anita, Sinsimer, Daniel, Backstrom, Jay T., Platzbecker, Uwe, Komrokji, Rami S.
Publicado 2022

Health-Related Quality of Life Outcomes in Patients with Myelodysplastic Syndromes with Ring Sideroblasts Treated with Luspatercept in the MEDALIST Phase 3 Trial

por Oliva, Esther Natalie, Platzbecker, Uwe, Garcia-Manero, Guillermo, Mufti, Ghulam J., Santini, Valeria, Sekeres, Mikkael A., Komrokji, Rami S., Shetty, Jeevan K., Tang, Derek, Guo, Shien, Liao, Weiqin, Zhang, George, Ha, Xianwei, Ito, Rodrigo, Lord-Bessen, Jennifer, Backstrom, Jay T., Fenaux, Pierre
Publicado 2021

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

por Guerenne, Laura, Beurlet, Stéphanie, Said, Mohamed, Gorombei, Petra, Le Pogam, Carole, Guidez, Fabien, de la Grange, Pierre, Omidvar, Nader, Vanneaux, Valérie, Mills, Ken, Mufti, Ghulam J, Sarda-Mantel, Laure, Noguera, Maria Elena, Pla, Marika, Fenaux, Pierre, Padua, Rose Ann, Chomienne, Christine, Krief, Patricia
Publicado 2016

Application of the pMHC Array to Characterise Tumour Antigen Specific T Cell Populations in Leukaemia Patients at Disease Diagnosis

por Brooks, Suzanne E., Bonney, Stephanie A., Lee, Cindy, Publicover, Amy, Khan, Ghazala, Smits, Evelien L., Sigurdardottir, Dagmar, Arno, Matthew, Li, Demin, Mills, Ken I., Pulford, Karen, Banham, Alison H., van Tendeloo, Viggo, Mufti, Ghulam J., Rammensee, Hans-Georg, Elliott, Tim J., Orchard, Kim H., Guinn, Barbara-ann
Publicado 2015