Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models

por Mu-Mosley, Hong, Ostermann, Lauren, Muftuoglu, Muharrem, Vaidya, Abishek, Bonifant, Challice L., Velasquez, Mireya Paulina, Gottschalk, Stephen, Andreeff, Michael
Publicado 2022

Extended live-cell barcoding approach for multiplexed mass cytometry

por Muftuoglu, Muharrem, Li, Li, Liang, Shaoheng, Mak, Duncan, Lin, Angelique J., Fang, Junxiang, Burks, Jared K., Chen, Ken, Andreeff, Michael
Publicado 2021

In-depth analysis of SARS-CoV-2–specific T cells reveals diverse differentiation hierarchies in vaccinated individuals

por Li, Li, Muftuoglu, Muharrem, Liang, Shaoheng, Basyal, Mahesh, LV, Jiangxing, Akdogan, Mehmet Emin, Chen, Ken, Andreeff, Michael, Flowers, Christopher R., Parmar, Simrit
Publicado 2022

Evidence for B Cell Exhaustion in Chronic Graft-versus-Host Disease

por Khoder, Ahmad, Alsuliman, Abdullah, Basar, Rafet, Sobieski, Catherine, Kondo, Kayo, Alousi, Amin Majid, Szydlo, Richard, Muftuoglu, Muharrem, Shaim, Hila, Apperley, Jane F., Gokdemir, Elif, Cooper, Nichola, Mehta, Rohtesh S., Marin, David, Champlin, Richard, Shpall, Elizabeth, Rezvani, Katayoun
Publicado 2018

Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

por Carter, Bing Z., Mak, Po Yee, Tao, Wenjing, Ayoub, Edward, Ostermann, Lauren B., Huang, Xuelin, Loghavi, Sanam, Boettcher, Steffen, Nishida, Yuki, Ruvolo, Vivian, Hughes, Paul E., Morrow, Phuong K., Haferlach, Torsten, Kornblau, Steven, Muftuoglu, Muharrem, Andreeff, Michael
Publicado 2023

Correction: Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics

por Carter, Bing Z., Mak, Po Yee, Tao, Wenjing, Ayoub, Edward, Ostermann, Lauren B., Huang, Xuelin, Loghavi, Sanam, Boettcher, Steffen, Nishida, Yuki, Ruvolo, Vivian, Hughes, Paul E., Morrow, Phuong K., Haferlach, Torsten, Kornblau, Steven, Muftuoglu, Muharrem, Andreeff, Michael
Publicado 2023

Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias

por Nishida, Yuki, Ishizawa, Jo, Ayoub, Edward, Montoya, Rafael Heinz, Ostermann, Lauren B., Muftuoglu, Muharrem, Ruvolo, Vivian R, Patsilevas, Tallie, Scruggs, Darah A., Khazaei, Shayaun, Mak, Po Yee, Tao, Wenjing, Carter, Bing Z., Boettcher, Steffen, Ebert, Benjamin L., Daver, Naval G., Konopleva, Marina, Seki, Takahiko, Kojima, Kensuke, Andreeff, Michael
Publicado 2023

The CXCR4–STAT3–IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia and Is Modulated by Lenalidomide

por Shaim, Hila, Estrov, Zeev, Harris, David, Hernandez Sanabria, Mayra, Liu, Zhiming, Ruvolo, Peter, Thompson, Phillip A., Ferrajoli, Alessandra, Daher, May, Burger, Jan, Muftuoglu, Muharrem, Imahashi, Nobuhiko, Li, Li, Liu, Enli, Alsuliman, Abdullah Saleh, Basar, Rafet, Nassif Kerbauy, Lucila, Sobieski, Catherine, Gokdemir, Elif, Kondo, Kayo, Wierda, William, Keating, Michael, Shpall, Elizabeth J., Rezvani, Katayoun
Publicado 2018

A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative an...

por Senapati, Jayastu, Muftuoglu, Muharrem, Ishizawa, Jo, Abbas, Hussein A., Loghavi, Sanam, Borthakur, Gautam, Yilmaz, Musa, Issa, Ghayas C., Dara, Samuel I., Basyal, Mahesh, Li, Li, Naqvi, Kiran, Pourebrahim, Rasoul, Jabbour, Elias J., Kornblau, Steven M., Short, Nicholas J., Pemmaraju, Naveen, Garcia-Manero, Guillermo, Ravandi, Farhad, Khoury, Joseph, Daver, Naval, Kantarjian, Hagop M., Andreeff, Michael, DiNardo, Courtney D.
Publicado 2023

A phase 1/2 study of azacitidine, venetoclax and pevonedistat in newly diagnosed secondary AML and in MDS or CMML after failure of hypomethylating agents

por Short, Nicholas J., Muftuoglu, Muharrem, Ong, Faustine, Nasr, Lewis, Macaron, Walid, Montalban-Bravo, Guillermo, Alvarado, Yesid, Basyal, Mahesh, Daver, Naval, Dinardo, Courtney D., Borthakur, Gautam, Jain, Nitin, Ohanian, Maro, Jabbour, Elias, Issa, Ghayas C., Qiao, Wei, Huang, Xuelin, Kanagal-Shamanna, Rashmi, Patel, Keyur P., Bose, Prithviraj, Ravandi, Farhad, Delumpa, Ricardo, Abramova, Regina, Garcia-Manero, Guillermo, Andreeff, Michael, Cortes, Jorge, Kantarjian, Hagop
Publicado 2023

Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy

por Ganan-Gomez, Irene, Yang, Hui, Ma, Feiyang, Montalban-Bravo, Guillermo, Thongon, Natthakan, Marchica, Valentina, Richard-Carpentier, Guillaume, Chien, Kelly, Manyam, Ganiraju, Wang, Feng, Alfonso, Ana, Chen, Shuaitong, Class, Caleb, Kanagal-Shamanna, Rashmi, Ingram, Justin P., Ogoti, Yamini, Rose, Ashley, Loghavi, Sanam, Lockyer, Pamela, Cambo, Benedetta, Muftuoglu, Muharrem, Schneider, Sarah, Adema, Vera, McLellan, Michael, Garza, John, Marchesini, Matteo, Giuliani, Nicola, Pellegrini, Matteo, Wang, Jing, Walker, Jason, Li, Ziyi, Takahashi, Koichi, Leverson, Joel D., Bueso-Ramos, Carlos, Andreeff, Michael, Clise-Dwyer, Karen, Garcia-Manero, Guillermo, Colla, Simona
Publicado 2022

Author Correction: Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy

por Ganan-Gomez, Irene, Yang, Hui, Ma, Feiyang, Montalban-Bravo, Guillermo, Thongon, Natthakan, Marchica, Valentina, Richard-Carpentier, Guillaume, Chien, Kelly, Manyam, Ganiraju, Wang, Feng, Alfonso, Ana, Chen, Shuaitong, Class, Caleb, Kanagal-Shamanna, Rashmi, Ingram, Justin P., Ogoti, Yamini, Rose, Ashley, Loghavi, Sanam, Lockyer, Pamela, Cambo, Benedetta, Muftuoglu, Muharrem, Schneider, Sarah, Adema, Vera, McLellan, Michael, Garza, John, Marchesini, Matteo, Giuliani, Nicola, Pellegrini, Matteo, Wang, Jing, Walker, Jason, Li, Ziyi, Takahashi, Koichi, Leverson, Joel D., Bueso-Ramos, Carlos, Andreeff, Michael, Clise-Dwyer, Karen, Garcia-Manero, Guillermo, Colla, Simona
Publicado 2022

Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA CCAT2 induce myeloid malignancies via unique SNP-specific RNA mutations

por Shah, Maitri Y., Ferracin, Manuela, Pileczki, Valentina, Chen, Baoqing, Redis, Roxana, Fabris, Linda, Zhang, Xinna, Ivan, Cristina, Shimizu, Masayoshi, Rodriguez-Aguayo, Cristian, Dragomir, Mihnea, Van Roosbroeck, Katrien, Almeida, Maria Ines, Ciccone, Maria, Nedelcu, Daniela, Cortez, Maria Angelica, Manshouri, Taghi, Calin, Steliana, Muftuoglu, Muharrem, Banerjee, Pinaki P., Badiwi, Mustafa H., Parker-Thornburg, Jan, Multani, Asha, Welsh, James William, Estecio, Marcos Roberto, Ling, Hui, Tomuleasa, Ciprian, Dima, Delia, Yang, Hui, Alvarez, Hector, You, M. James, Radovich, Milan, Shpall, Elizabeth, Fabbri, Muller, Rezvani, Katy, Girnita, Leonard, Berindan-Neagoe, Ioana, Maitra, Anirban, Verstovsek, Srdan, Fodde, Riccardo, Bueso-Ramos, Carlos, Gagea, Mihai, Manero, Guillermo Garcia, Calin, George A.
Publicado 2018