Combined over-expression of two cytochrome P450 genes exacerbates the fitness cost of pyrethroid resistance in the major African malaria vector Anopheles funestus

por Tchouakui, Magellan, Mugenzi, Leon M.J., Wondji, Murielle J., Tchoupo, Micareme, Njiokou, Flobert, Wondji, Charles S.
Publicado 2021

A 6.5kb Intergenic Structural Variation Exacerbates the Fitness Cost of P450-Based Metabolic Resistance in the Major African Malaria Vector Anopheles funestus

por Tchouakui, Magellan, Mugenzi, Leon M. J., Wondji, Murielle J., Tchoupo, Micareme, Njiokou, Flobert, Wondji, Charles S.
Publicado 2022

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector Anopheles funestus but PBO-Based Olyse...

por Menze, Benjamin D., Mugenzi, Leon M. J., Tchouakui, Magellan, Wondji, Murielle J., Tchoupo, Micareme, Wondji, Charles S.
Publicado 2022

Reduced performance of community bednets against pyrethroid-resistant Anopheles funestus and Anopheles gambiae, major malaria vectors in Cameroon

por Ngongang-Yipmo, Emilie S., Tchouakui, Magellan, Menze, Benjamin D., Mugenzi, Leon M. J., Njiokou, Flobert, Wondji, Charles S.
Publicado 2022

Genetic Diversity of Cytochrome P450s CYP6M2 and CYP6P4 Associated with Pyrethroid Resistance in the Major Malaria Vectors Anopheles coluzzii and Anopheles gambiae from Yaoundé, Ca...

por Fotso-Toguem, Yvan, Tene-Fossog, Billy, Mugenzi, Leon M. J., Wondji, Murielle J., Njiokou, Flobert, Ranson, Hilary, Wondji, Charles S.
Publicado 2022

Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy

por Tchouakui, Magellan, Mugenzi, Leon M. J., D. Menze, Benjamin, Khaukha, Jude N. T., Tchapga, Williams, Tchoupo, Micareme, Wondji, Murielle J., Wondji, Charles S.
Publicado 2021

Molecular Drivers of Multiple and Elevated Resistance to Insecticides in a Population of the Malaria Vector Anopheles gambiae in Agriculture Hotspot of West Cameroon

por Tepa, Arnaud, Kengne-Ouafo, Jonas A., Djova, Valdi S., Tchouakui, Magellan, Mugenzi, Leon M. J., Djouaka, Rousseau, Pieme, Constant A., Wondji, Charles S.
Publicado 2022

Contrasting Patterns of Asaia Association with Pyrethroid Resistance Escalation between the Malaria Vectors Anopheles funestus and Anopheles gambiae

por Djondji Kamga, Fleuriane Metissa, Mugenzi, Leon M. J., Tchouakui, Magellan, Sandeu, Maurice Marcel, Maffo, Claudine Grace Tatsinkou, Nyegue, Maximilienne Ascension, Wondji, Charles S.
Publicado 2023

The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus

por Mugenzi, Leon M. J., A. Tekoh, Theofelix, S. Ibrahim, Sulaiman, Muhammad, Abdullahi, Kouamo, Mersimine, Wondji, Murielle J., Irving, Helen, Hearn, Jack, Wondji, Charles S.
Publicado 2023

Evidence of intensification of pyrethroid resistance in the major malaria vectors in Kinshasa, Democratic Republic of Congo

por Nguiffo-Nguete, Daniel, Mugenzi, Leon M. J., Manzambi, Emile Zola, Tchouakui, Magellan, Wondji, Murielle, Tekoh, Theofelix, Watsenga, Francis, Agossa, Fiacre, Wondji, Charles S.
Publicado 2023

Correction: Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus

por Tchouakui, Magellan, Riveron Miranda, Jacob, Mugenzi, Leon M. J., Djonabaye, Doumani, Wondji, Murielle J., Tchoupo, Micareme, Tchapga, Williams, Njiokou, Flobert, Wondji, Charles S.
Publicado 2020

Marked aggravation of pyrethroid resistance in major malaria vectors in Malawi between 2014 and 2021 is partly linked with increased expression of P450 alleles

por Menze, Benjamin D., Tchouakui, Magellan, Mugenzi, Leon M. J., Tchapga, Williams, Tchoupo, Micareme, Wondji, Murielle J., Chiumia, Martin, Mzilahowa, Themba, Wondji, Charles S.
Publicado 2022

Entomological longitudinal surveys in two contrasted eco-climatic settings in Cameroon reveal a high malaria transmission from Anopheles funestus associated with GSTe2 metabolic re...

por Natchema S. Fonkou, Brice, Tchouakui, Magellan, Menze, Benjamin D., Mugenzi, Leon M. J., Fofie, Derrick, Nguiffo-Nguete, Daniel, Nkengazong, Lucia, Tombi, Jeannette, Wondji, Charles S.
Publicado 2023

Multi‐omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa

por Hearn, Jack, Djoko Tagne, Carlos S., Ibrahim, Sulaiman S., Tene‐Fossog, Billy, Mugenzi, Leon M. J., Irving, Helen, Riveron, Jacob M., Weedall, Gareth D., Wondji, Charles S.
Publicado 2022

Xeno-monitoring of molecular drivers of artemisinin and partner drug resistance in P. falciparum populations in malaria vectors across Cameroon

por Nkemngo, Francis N., Mugenzi, Leon M.J., Tchouakui, Magellan, Nguiffo-Nguete, Daniel, Wondji, Murielle J., Mbakam, Bertrand, Tchoupo, Micareme, Ndo, Cyrille, Wanji, Samuel, Wondji, Charles S.
Publicado 2022

Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus

por Mugenzi, Leon M. J., Menze, Benjamin D., Tchouakui, Magellan, Wondji, Murielle J., Irving, Helen, Tchoupo, Micareme, Hearn, Jack, Weedall, Gareth D., Riveron, Jacob M., Wondji, Charles S.
Publicado 2019

Comparative study of the effect of solvents on the efficacy of neonicotinoid insecticides against malaria vector populations across Africa

por Tchouakui, Magellan, Assatse, Tatiane, Mugenzi, Leon M. J., Menze, Benjamin D., Nguiffo-Nguete, Daniel, Tchapga, Williams, Kayondo, Jonathan, Watsenga, Francis, Manzambi, Emile Zola, Osae, Michael, Wondji, Charles S.
Publicado 2022

Detection of a reduced susceptibility to chlorfenapyr in the malaria vector Anopheles gambiae contrasts with full susceptibility in Anopheles funestus across Africa

por Tchouakui, Magellan, Assatse, Tatiane, Tazokong, Hervé R., Oruni, Ambrose, Menze, Benjamin D., Nguiffo-Nguete, Daniel, Mugenzi, Leon M. J., Kayondo, Jonathan, Watsenga, Francis, Mzilahowa, Themba, Osae, Michael, Wondji, Charles S.
Publicado 2023

Escalating pyrethroid resistance in two major malaria vectors Anopheles funestus and Anopheles gambiae (s.l.) in Atatam, Southern Ghana

por Mugenzi, Leon M. J., Akosah-Brempong, Gabriel, Tchouakui, Magellan, Menze, Benjamin D., Tekoh, Theofelix A., Tchoupo, Micareme, Nkemngo, Francis N., Wondji, Murielle J., Nwaefuna, Ekene K., Osae, Michael, Wondji, Charles S.
Publicado 2022

Epidemiology of malaria, schistosomiasis, and geohelminthiasis amongst children 3–15 years of age during the dry season in Northern Cameroon

por Nkemngo, Francis N., W. G. Raissa, Lymen, Nebangwa, Derrick N., Nkeng, Asongha M., Kengne, Alvine, Mugenzi, Leon M. J., Fotso-Toguem, Yvan G., Wondji, Murielle J., Shey, Robert A., Nguiffo-Nguete, Daniel, Fru-Cho, Jerome, Ndo, Cyrille, Njiokou, Flobert, Webster, Joanne P., Wanji, Samuel, Wondji, Charles S.
Publicado 2023