Is smaller better? Vaccine targeting recombinant receptor-binding domain might hold the key for mass production of effective prophylactics to fight the COVID-19 pandemic

por Muhuri, Manish, Gao, Guangping
Publicado 2020

Editorial: Immunogenicity and toxicity of AAV gene therapy

por Bradbury, Allison, Markusic, David, Muhuri, Manish, Ou, Li
Publicado 2023

Vectored Immunotherapeutics for Infectious Diseases: Can rAAVs Be The Game Changers for Fighting Transmissible Pathogens?

por Zhan, Wei, Muhuri, Manish, Tai, Phillip W. L., Gao, Guangping
Publicado 2021

Durability of transgene expression after rAAV gene therapy

por Muhuri, Manish, Levy, Daniel I., Schulz, Martin, McCarty, Douglas, Gao, Guangping
Publicado 2022

Docosanoic acid conjugation to siRNA enables functional and safe delivery to skeletal and cardiac muscles

por Biscans, Annabelle, Caiazzi, Jillian, McHugh, Nicholas, Hariharan, Vignesh, Muhuri, Manish, Khvorova, Anastasia
Publicado 2021

MicroRNA-138 is a Prognostic Biomarker for Triple-Negative Breast Cancer and Promotes Tumorigenesis via TUSC2 repression

por Nama, Srikanth, Muhuri, Manish, Di Pascale, Federica, Quah, Shan, Aswad, Luay, Fullwood, Melissa, Sampath, Prabha
Publicado 2019

Modulating immune responses to AAV by expanded polyclonal T-regs and capsid specific chimeric antigen receptor T-regulatory cells

por Arjomandnejad, Motahareh, Sylvia, Katelyn, Blackwood, Meghan, Nixon, Thomas, Tang, Qiushi, Muhuri, Manish, Gruntman, Alisha M., Gao, Guangping, Flotte, Terence R., Keeler, Allison M.
Publicado 2021

C/EBPβ mediates RNA polymerase III-driven transcription of oncomiR-138 in malignant gliomas

por Di Pascale, Federica, Nama, Srikanth, Muhuri, Manish, Quah, Shan, Ismail, Hisyam M, Chan, Xin Hui Derryn, Sundaram, Gopinath M, Ramalingam, Rajkumar, Burke, Brian, Sampath, Prabha
Publicado 2018

EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis

por Sundaram, Gopinath M., Ismail, Hisyam M., Bashir, Mohsin, Muhuri, Manish, Vaz, Candida, Nama, Srikanth, Ow, Ghim Siong, Vladimirovna, Ivshina Anna, Ramalingam, Rajkumar, Burke, Brian, Tanavde, Vivek, Kuznetsov, Vladimir, Lane, E. Birgitte, Sampath, Prabha
Publicado 2017

Novel Combinatorial MicroRNA-Binding Sites in AAV Vectors Synergistically Diminish Antigen Presentation and Transgene Immunity for Efficient and Stable Transduction

por Muhuri, Manish, Zhan, Wei, Maeda, Yukiko, Li, Jia, Lotun, Anoushka, Chen, Jennifer, Sylvia, Katelyn, Dasgupta, Ishani, Arjomandnejad, Motahareh, Nixon, Thomas, Keeler, Allison M., Manokaran, Sangeetha, He, Ran, Su, Qin, Tai, Phillip W. L., Gao, Guangping
Publicado 2021

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

por Hariharan, Vignesh N., Shin, Minwook, Chang, Ching-Wen, O’Reilly, Daniel, Biscans, Annabelle, Yamada, Ken, Guo, Zhiru, Somasundaran, Mohan, Tang, Qi, Monopoli, Kathryn, Krishnamurthy, Pranathi Meda, Devi, Gitali, McHugh, Nicholas, Cooper, David A., Echeverria, Dimas, Cruz, John, Chan, Io Long, Liu, Ping, Lim, Sun-Young, McConnell, Jill, Singh, Satya Prakash, Hildebrand, Samuel, Sousa, Jacquelyn, Davis, Sarah M., Kennedy, Zachary, Ferguson, Chantal, Godinho, Bruno M. D. C., Thillier, Yann, Caiazzi, Jillian, Ly, Socheata, Muhuri, Manish, Kelly, Karen, Humphries, Fiachra, Cousineau, Alyssa, Parsi, Krishna Mohan, Li, Qi, Wang, Yang, Maehr, René, Gao, Guangping, Korkin, Dmitry, McDougall, William M., Finberg, Robert W., Fitzgerald, Katherine A., Wang, Jennifer P., Watts, Jonathan K., Khvorova, Anastasia
Publicado 2023