Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure–Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of C...

por Hudson, Liam, Mui, James, Vázquez, Santiago, Carvalho, Diana M., Williams, Eleanor, Jones, Chris, Bullock, Alex N., Hoelder, Swen
Publicado 2018

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

por Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Publicado 2019