Advanced Understanding of Monogenic Inflammatory Bowel Disease

por Nambu, Ryusuke, Muise, Aleixo M.
Publicado 2021

TTC7A: Steward of Intestinal Health

por Jardine, Sasha, Dhingani, Neel, Muise, Aleixo M.
Publicado 2018

Association Between a Multi-Locus Genetic Risk Score and Inflammatory Bowel Disease

por Hu, Pingzhao, Muise, Aleixo M., Xing, Xiang, Brumell, John H., Silverberg, Mark S., Xu, Wei
Publicado 2013

Host and bacterial factors that regulate LC3 recruitment to Listeria monocytogenes during the early stages of macrophage infection

por Lam, Grace Y., Cemma, Marija, Muise, Aleixo M., Higgins, Darren E., Brumell, John H.
Publicado 2013

ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells

por Leung, Gabriella, Zhou, Yuhuan, Ostrowski, Philip, Mylvaganam, Sivakami, Boroumand, Parastoo, Mulder, Daniel J., Guo, Conghui, Muise, Aleixo M., Freeman, Spencer A.
Publicado 2021

Rac2-Deficiency Leads to Exacerbated and Protracted Colitis in Response to Citrobacter rodentium Infection

por Fattouh, Ramzi, Guo, Cong-Hui, Lam, Grace Y., Gareau, Melanie G., Ngan, Bo-Yee, Glogauer, Michael, Muise, Aleixo M., Brumell, John H.
Publicado 2013

Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread

por Czuczman, Mark A., Fattouh, Ramzi, van Rijn, Jorik, Canadien, Veronica, Osborne, Suzanne, Muise, Aleixo M., Kuchroo, Vijay K., Higgins, Darren E., Brumell, John H.
Publicado 2014

Utilization of Whole Exome Sequencing Data to Identify Clinically Relevant Pharmacogenomic Variants in Pediatric Inflammatory Bowel Disease

por Mulder, Daniel J., Khalouei, Sam, Warner, Neil, Gonzaga-Jauregui, Claudia, Church, Peter C., Walters, Thomas D., Ramani, Arun K., Griffiths, Anne M., Cohn, Iris, Muise, Aleixo M.
Publicado 2020

R-Spondin 2 signaling mediates susceptibility to fatal infectious diarrhea

por Papapietro, Olivier, Teatero, Sarah, Thanabalasuriar, Ajitha, Yuki, Kyoko E., Diez, Eduardo, Zhu, Lei, Kang, Eugene, Dhillon, Sandeep, Muise, Aleixo M., Durocher, Yves, Marcinkiewicz, Martin M., Malo, Danielle, Gruenheid, Samantha
Publicado 2013

The E3 ubiquitin ligase UBR5 interacts with TTC7A and may be associated with very early onset inflammatory bowel disease

por Dhingani, Neel, Guo, Conghui, Pan, Jie, Li, Qi, Warner, Neil, Jardine, Sasha, Leung, Gabriella, Kotlarz, Daniel, Gonzaga-Jauregui, Claudia, Klein, Christoph, Snapper, Scott B., Navas-López, Víctor Manuel, Muise, Aleixo M.
Publicado 2020

Chromosomal Numerical Aberrations and Rare Copy Number Variation in Patients with Inflammatory Bowel Disease

por Dirvanskyte, Paulina, Gurram, Bhaskar, Bolton, Chrissy, Warner, Neil, Jones, Kelsey D J, Griffin, Helen R, Park, Jason Y, Keller, Klaus-Michael, Gilmour, Kimberly C, Hambleton, Sophie, Muise, Aleixo M, Wysocki, Christian, Uhlig, Holm H
Publicado 2022

Pathogenic Interleukin-10 Receptor Alpha Variants in Humans — Balancing Natural Selection and Clinical Implications

por Aschenbrenner, Dominik, Ye, Ziqing, Zhou, Ying, Hu, Wenhui, Brooks, Isabel, Williams, Isabelle, Capitani, Melania, Gartner, Lisa, Kotlarz, Daniel, Snapper, Scott B., Klein, Christoph, Muise, Aleixo M., Marsden, Brian D., Huang, Ying, Uhlig, Holm H.
Publicado 2022

Valosin-containing protein-regulated endoplasmic reticulum stress causes NOD2-dependent inflammatory responses

por Ghalandary, Maryam, Li, Yue, Fröhlich, Thomas, Magg, Thomas, Liu, Yanshan, Rohlfs, Meino, Hollizeck, Sebastian, Conca, Raffaele, Schwerd, Tobias, Uhlig, Holm H., Bufler, Philip, Koletzko, Sibylle, Muise, Aleixo M., Snapper, Scott B., Hauck, Fabian, Klein, Christoph, Kotlarz, Daniel
Publicado 2022

Higher Activity of the Inducible Nitric Oxide Synthase Contributes to Very Early Onset Inflammatory Bowel Disease

por Dhillon, Sandeep S, Mastropaolo, Lucas A, Murchie, Ryan, Griffiths, Christopher, Thöni, Cornelia, Elkadri, Abdul, Xu, Wei, Mack, Amanda, Walters, Thomas, Guo, Conghui, Mack, David, Huynh, Hien, Baksh, Shairaz, Silverberg, Mark S, Brumell, John H, Snapper, Scott B, Muise, Aleixo M
Publicado 2014

Mutations in Plasmalemma Vesicle Associated Protein Result in Sieving Protein-Losing Enteropathy Characterized by Hypoproteinemia, Hypoalbuminemia, and Hypertriglyceridemia

por Elkadri, Abdul, Thoeni, Cornelia, Deharvengt, Sophie J., Murchie, Ryan, Guo, Conghui, Stavropoulos, James D., Marshall, Christian R., Wales, Paul, Bandsma, Robert H.J., Cutz, Ernest, Roifman, Chaim M., Chitayat, David, Avitzur, Yaron, Stan, Radu V., Muise, Aleixo M.
Publicado 2015

Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease

por Horowitz, Julie E., Warner, Neil, Staples, Jeffrey, Crowley, Eileen, Gosalia, Nehal, Murchie, Ryan, Van Hout, Cristopher, Fiedler, Karoline, Welch, Gabriel, King, Alejandra Klauer, Reid, Jeffrey G., Overton, John D., Baras, Aris, Shuldiner, Alan R., Griffiths, Anne, Gottesman, Omri, Muise, Aleixo M., Gonzaga-Jauregui, Claudia
Publicado 2021

Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease

por Bosa, Luca, Batura, Vritika, Colavito, Davide, Fiedler, Karoline, Gaio, Paola, Guo, Conghui, Li, Qi, Marzollo, Antonio, Mescoli, Claudia, Nambu, Ryusuke, Pan, Jie, Perilongo, Giorgio, Warner, Neil, Zhang, Shiqi, Kotlarz, Daniel, Klein, Christoph, Snapper, Scott B., Walters, Thomas D., Leon, Alberta, Griffiths, Anne M., Cananzi, Mara, Muise, Aleixo M.
Publicado 2021

Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis

por Parlato, Marianna, Charbit‐Henrion, Fabienne, Pan, Jie, Romano, Claudio, Duclaux‐Loras, Rémi, Le Du, Marie‐Helene, Warner, Neil, Francalanci, Paola, Bruneau, Julie, Bras, Marc, Zarhrate, Mohammed, Bègue, Bernadette, Guegan, Nicolas, Rakotobe, Sabine, Kapel, Nathalie, De Angelis, Paola, Griffiths, Anne M, Fiedler, Karoline, Crowley, Eileen, Ruemmele, Frank, Muise, Aleixo M, Cerf‐Bensussan, Nadine
Publicado 2018

Loss of the Arp2/3 complex component ARPC1B causes platelet abnormalities and predisposes to inflammatory disease

por Kahr, Walter H. A., Pluthero, Fred G., Elkadri, Abdul, Warner, Neil, Drobac, Marko, Chen, Chang Hua, Lo, Richard W., Li, Ling, Li, Ren, Li, Qi, Thoeni, Cornelia, Pan, Jie, Leung, Gabriella, Lara-Corrales, Irene, Murchie, Ryan, Cutz, Ernest, Laxer, Ronald M., Upton, Julia, Roifman, Chaim M., Yeung, Rae S. M., Brumell, John H, Muise, Aleixo M
Publicado 2017

Defects in Nicotinamide-adenine Dinucleotide Phosphate Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

por Hayes, Patti, Dhillon, Sandeep, O’Neill, Kim, Thoeni, Cornelia, Hui, Ken Y., Elkadri, Abdul, Guo, Conghui H., Kovacic, Lidija, Aviello, Gabriella, Alvarez, Luis A., Griffiths, Anne M., Snapper, Scott B., Brant, Steven R., Doroshow, James H., Silverberg, Mark S., Peter, Inga, McGovern, Dermot P.B., Cho, Judy, Brumell, John H., Uhlig, Holm H., Bourke, Billy, Muise, Aleixo M., Knaus, Ulla G.
Publicado 2015