Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition

por Yosaatmadja, Yuliana, Baddock, Hannah T, Newman, Joseph A, Bielinski, Marcin, Gavard, Angeline E, Mukhopadhyay, Shubhashish M M, Dannerfjord, Adam A, Schofield, Christopher J, McHugh, Peter J, Gileadi, Opher
Publicado 2021

Identification, mapping and relative quantitation of SARS-CoV-2 Spike glycopeptides by Mass-Retention Time Fingerprinting

por Chalk, Rod, Greenland, William E. P., Moreira, Tiago, Coker, Jesse, Mukhopadhyay, Shubhashish M. M., Williams, Eleanor, Manning, Charlotte, Bohstedt, Tina, McCrorie, Rama, Fernandez-Cid, Alejandra, Burgess-Brown, Nicola A.
Publicado 2021

Structural characterization of human urea transporters UT-A and UT-B and their inhibition

por Chi, Gamma, Dietz, Larissa, Tang, Haiping, Snee, Matthew, Scacioc, Andreea, Wang, Dong, Mckinley, Gavin, Mukhopadhyay, Shubhashish M. M., Pike, Ashley C. W., Chalk, Rod, Burgess-Brown, Nicola A., Timmermans, Jean-Pierre, van Putte, Wouter, Robinson, Carol V., Dürr, Katharina L.
Publicado 2023

Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

por Chi, Gamma, Liang, Qiansheng, Sridhar, Akshay, Cowgill, John B., Sader, Kasim, Radjainia, Mazdak, Qian, Pu, Castro-Hartmann, Pablo, Venkaya, Shayla, Singh, Nanki Kaur, McKinley, Gavin, Fernandez-Cid, Alejandra, Mukhopadhyay, Shubhashish M. M., Burgess-Brown, Nicola A., Delemotte, Lucie, Covarrubias, Manuel, Dürr, Katharina L.
Publicado 2022

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

por Bushell, Simon R., Pike, Ashley C. W., Falzone, Maria E., Rorsman, Nils J. G., Ta, Chau M., Corey, Robin A., Newport, Thomas D., Christianson, John C., Scofano, Lara F., Shintre, Chitra A., Tessitore, Annamaria, Chu, Amy, Wang, Qinrui, Shrestha, Leela, Mukhopadhyay, Shubhashish M. M., Love, James D., Burgess-Brown, Nicola A., Sitsapesan, Rebecca, Stansfeld, Phillip J., Huiskonen, Juha T., Tammaro, Paolo, Accardi, Alessio, Carpenter, Elisabeth P.
Publicado 2019

Phospho‐regulation, nucleotide binding and ion access control in potassium‐chloride cotransporters

por Chi, Gamma, Ebenhoch, Rebecca, Man, Henry, Tang, Haiping, Tremblay, Laurence E, Reggiano, Gabriella, Qiu, Xingyu, Bohstedt, Tina, Liko, Idlir, Almeida, Fernando G, Garneau, Alexandre P, Wang, Dong, McKinley, Gavin, Moreau, Christophe P, Bountra, Kiran D, Abrusci, Patrizia, Mukhopadhyay, Shubhashish M M, Fernandez‐Cid, Alejandra, Slimani, Samira, Lavoie, Julie L, Burgess‐Brown, Nicola A, Tehan, Ben, DiMaio, Frank, Jazayeri, Ali, Isenring, Paul, Robinson, Carol V, Dürr, Katharina L
Publicado 2021

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design

por Dong, Yin Yao, Wang, Hua, Pike, Ashley C.W., Cochrane, Stephen A., Hamedzadeh, Sadra, Wyszyński, Filip J., Bushell, Simon R., Royer, Sylvain F., Widdick, David A., Sajid, Andaleeb, Boshoff, Helena I., Park, Yumi, Lucas, Ricardo, Liu, Wei-Min, Lee, Seung Seo, Machida, Takuya, Minall, Leanne, Mehmood, Shahid, Belaya, Katsiaryna, Liu, Wei-Wei, Chu, Amy, Shrestha, Leela, Mukhopadhyay, Shubhashish M.M., Strain-Damerell, Claire, Chalk, Rod, Burgess-Brown, Nicola A., Bibb, Mervyn J., Barry III, Clifton E., Robinson, Carol V., Beeson, David, Davis, Benjamin G., Carpenter, Elisabeth P.
Publicado 2018