Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft model

por de Boeck, Miriam, Cui, Chao, Mulder, Aat A, Jost, Carolina R, Ikeno, Souichi, ten Dijke, Peter
Publicado 2016

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity

por Alves, C. Henrique, Boon, Nanda, Mulder, Aat A., Koster, Abraham J., Jost, Carolina R., Wijnholds, Jan
Publicado 2019

Sec22b determines Weibel-Palade body length by controlling anterograde endoplasmic reticulum-Golgi transport

por Karampini, Ellie, Bürgisser, Petra E., Olins, Jenny, Mulder, Aat A., Jost, Carolina R., Geerts, Dirk, Voorberg, Jan, Bierings, Ruben
Publicado 2020

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Family Members With a Pathogenic NOTCH3 Variant Can Have a Normal Brain Magnetic Resonanc...

por Hack, Remco J., Gravesteijn, Gido, Cerfontaine, Minne N., Hegeman, Ingrid M., Mulder, Aat A., Lesnik Oberstein, Saskia A.J., Rutten, Julie W.
Publicado 2022

Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision

por Tuijtel, Maarten W., Mulder, Aat A., Posthuma, Clara C., van der Hoeven, Barbara, Koster, Abraham J., Bárcena, Montserrat, Faas, Frank G. A., Sharp, Thomas H.
Publicado 2017

NO TCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature

por Gravesteijn, Gido, Hack, Remco J., Mulder, Aat A., Cerfontaine, Minne N., van Doorn, Remco, Hegeman, Ingrid M., Jost, Carolina R., Rutten, Julie W., Lesnik Oberstein, Saskia A. J.
Publicado 2021

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1

por Boon, Nanda, Alves, C. Henrique, Mulder, Aat A., Andriessen, Charlotte A., Buck, Thilo M., Quinn, Peter M. J., Vos, Rogier M., Koster, Abraham J., Jost, Carolina R., Wijnholds, Jan
Publicado 2021

High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II

por van Hoolwerff, Marcella, Rodríguez Ruiz, Alejandro, Bouma, Marga, Suchiman, H. Eka D., Koning, Roman I., Jost, Carolina R., Mulder, Aat A., Freund, Christian, Guilak, Farshid, Ramos, Yolande F. M., Meulenbelt, Ingrid
Publicado 2021

Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture

por Kat, Marije, Karampini, Ellie, Hoogendijk, Arie J., Bürgisser, Petra E., Mulder, Aat A., van Alphen, Floris P.J., Olins, Jenny, Geerts, Dirk, van den Biggelaar, Maartje, Margadant, Coert, Voorberg, Jan, Bierings, Ruben
Publicado 2022

In vitro modelling of alveolar repair at the air-liquid interface using alveolar epithelial cells derived from human induced pluripotent stem cells

por van Riet, Sander, Ninaber, Dennis K., Mikkers, Harald M. M., Tetley, Teresa D., Jost, Carolina R., Mulder, Aat A., Pasman, Thijs, Baptista, Danielle, Poot, André A., Truckenmüller, Roman, Mummery, Christine L., Freund, Christian, Rottier, Robbert J., Hiemstra, Pieter S.
Publicado 2020

Naturally occurring NOTCH3 exon skipping attenuates NOTCH3 protein aggregation and disease severity in CADASIL patients

por Gravesteijn, Gido, Dauwerse, Johannes G, Overzier, Maurice, Brouwer, Gwendolyn, Hegeman, Ingrid, Mulder, Aat A, Baas, Frank, Kruit, Mark C, Terwindt, Gisela M, van Duinen, Sjoerd G, Jost, Carolina R, Aartsma-Rus, Annemieke, Lesnik Oberstein, Saskia A J, Rutten, Julie W
Publicado 2020

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells

por Schillemans, Maaike, Karampini, Ellie, van den Eshof, Bart L., Gangaev, Anastasia, Hofman, Menno, van Breevoort, Dorothee, Meems, Henriët, Janssen, Hans, Mulder, Aat A., Jost, Carolina R., Escher, Johanna C., Adam, Rüdiger, Carter, Tom, Koster, Abraham J., van den Biggelaar, Maartje, Voorberg, Jan, Bierings, Ruben
Publicado 2018

Progression and Classification of Granular Osmiophilic Material (GOM) Deposits in Functionally Characterized Human NOTCH3 Transgenic Mice

por Gravesteijn, Gido, Munting, Leon P., Overzier, Maurice, Mulder, Aat A., Hegeman, Ingrid, Derieppe, Marc, Koster, Abraham J., van Duinen, Sjoerd G., Meijer, Onno C., Aartsma-Rus, Annemieke, van der Weerd, Louise, Jost, Carolina R., van den Maagdenberg, Arn M. J. M., Rutten, Julie W., Lesnik Oberstein, Saskia A. J.
Publicado 2019

CRB1 is required for recycling by RAB11A+ vesicles in human retinal organoids

por Buck, Thilo M., Quinn, Peter M.J., Pellissier, Lucie P., Mulder, Aat A., Jongejan, Aldo, Lu, Xuefei, Boon, Nanda, Koot, Daniëlle, Almushattat, Hind, Arendzen, Christiaan H., Vos, Rogier M., Bradley, Edward J., Freund, Christian, Mikkers, Harald M.M., Boon, Camiel J.F., Moerland, Perry D., Baas, Frank, Koster, Abraham J., Neefjes, Jacques, Berlin, Ilana, Jost, Carolina R., Wijnholds, Jan
Publicado 2023

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

por Quinn, Peter M., Buck, Thilo M., Mulder, Aat A., Ohonin, Charlotte, Alves, C. Henrique, Vos, Rogier M., Bialecka, Monika, van Herwaarden, Tessa, van Dijk, Elon H.C., Talib, Mays, Freund, Christian, Mikkers, Harald M.M., Hoeben, Rob C., Goumans, Marie-José, Boon, Camiel J.F., Koster, Abraham J., Chuva de Sousa Lopes, Susana M., Jost, Carolina R., Wijnholds, Jan
Publicado 2019

Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease

por Giacomelli, Elisa, Meraviglia, Viviana, Campostrini, Giulia, Cochrane, Amy, Cao, Xu, van Helden, Ruben W.J., Krotenberg Garcia, Ana, Mircea, Maria, Kostidis, Sarantos, Davis, Richard P., van Meer, Berend J., Jost, Carolina R., Koster, Abraham J., Mei, Hailiang, Míguez, David G., Mulder, Aat A., Ledesma-Terrón, Mario, Pompilio, Giulio, Sala, Luca, Salvatori, Daniela C.F., Slieker, Roderick C., Sommariva, Elena, de Vries, Antoine A.F., Giera, Martin, Semrau, Stefan, Tertoolen, Leon G.J., Orlova, Valeria V., Bellin, Milena, Mummery, Christine L.
Publicado 2020