Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data

por Cheng, Changde, Easton, John, Rosencrance, Celeste, Li, Yan, Ju, Bensheng, Williams, Justin, Mulder, Heather L, Pang, Yakun, Chen, Wenan, Chen, Xiang
Publicado 2019

Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor

por Flasch, Diane A., Chen, Xiaolong, Ju, Bensheng, Li, Xiaoyu, Dalton, James, Mulder, Heather L., Easton, John, Wang, Lu, Baker, Suzanne J., Chiang, Jason, Zhang, Jinghui
Publicado 2022

NSD2 E1099K drives relapse in pediatric acute lymphoblastic leukemia by disrupting 3D chromatin organization

por Narang, Sonali, Evensen, Nikki A., Saliba, Jason, Pierro, Joanna, Loh, Mignon L., Brown, Patrick A., Kolekar, Pandurang, Mulder, Heather, Shao, Ying, Easton, John, Ma, Xiaotu, Tsirigos, Aristotelis, Carroll, William L.
Publicado 2023

Association of Single-Nucleotide Variants in the Human Leukocyte Antigen and Other Loci With Childhood Hodgkin Lymphoma

por Chen, Cheng, Song, Nan, Dong, Qian, Sun, Xiaojun, Mulder, Heather L., Easton, John, Zhang, Jinghui, Yasui, Yutaka, Bhatia, Smita, Armstrong, Gregory T., Wang, Hui, Ness, Kirsten K., Hudson, Melissa M., Robison, Leslie L., Wang, Zhaoming
Publicado 2022

Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor

por Arunachalam, Sasi, Szlachta, Karol, Brady, Samuel W., Ma, Xiaotu, Ju, Bensheng, Shaner, Bridget, Mulder, Heather L., Easton, John, Raphael, Benjamin J., Myers, Matthew, Tinkle, Christopher, Allen, Sariah J., Orr, Brent A., Wetmore, Cynthia J., Baker, Suzanne J., Zhang, Jinghui
Publicado 2022

In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported

por Anekpuritanang, Tauangtham, Klairmont, Matthew M., Gradowski, Joel, Hagiwara, Kohei, Bailey, Nathanael G., Chandra, Pranil, Liu, Yiwei, Mulder, Heather L., Easton, John, Zhang, Jinghui, Martin, Michael G., Owczarczyk, Anna B., Dunlap, Jennifer B., Fan, Guang, Press, Richard D., Raess, Philipp W.
Publicado 2021

Dynamics of Age- versus Therapy-Related Clonal Hematopoiesis in Long-term Survivors of Pediatric Cancer

por Hagiwara, Kohei, Natarajan, Sivaraman, Wang, Zhaoming, Zubair, Haseeb, Mulder, Heather L., Dong, Li, Plyler, Emily M., Thimmaiah, Padma, Ma, Xiaotu, Ness, Kristen K., Li, Zhenghong, Mulrooney, Daniel A., Wilson, Carmen L., Yasui, Yutaka, Hudson, Melissa M., Easton, John, Robison, Leslie L., Zhang, Jinghui
Publicado 2023

Analysis of error profiles in deep next-generation sequencing data

por Ma, Xiaotu, Shao, Ying, Tian, Liqing, Flasch, Diane A., Mulder, Heather L., Edmonson, Michael N., Liu, Yu, Chen, Xiang, Newman, Scott, Nakitandwe, Joy, Li, Yongjin, Li, Benshang, Shen, Shuhong, Wang, Zhaoming, Shurtleff, Sheila, Robison, Leslie L., Levy, Shawn, Easton, John, Zhang, Jinghui
Publicado 2019

Social‐epigenetic mediators for racial disparities in pulmonary impairment among childhood cancer survivors

por Song, Nan, Dong, Qian, Chen, Cheng, Li, Qian, Mulder, Heather, Plyler, Emily, Easton, John, Walker, Emily, Olson, Scott, Neale, Geoffrey, Krull, Kevin R., Srivastava, Deo Kumar, Ness, Kirsten K., Zhang, Jinghui, Hudson, Melissa M., Robison, Leslie L., Huang, I‐Chan, Wang, Zhaoming
Publicado 2022

SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data

por Davis, Eric M., Sun, Yu, Liu, Yanling, Kolekar, Pandurang, Shao, Ying, Szlachta, Karol, Mulder, Heather L., Ren, Dongren, Rice, Stephen V., Wang, Zhaoming, Nakitandwe, Joy, Gout, Alexander M., Shaner, Bridget, Hall, Salina, Robison, Leslie L., Pounds, Stanley, Klco, Jeffery M., Easton, John, Ma, Xiaotu
Publicado 2021

Structure and evolution of double minutes in diagnosis and relapse brain tumors

por Xu, Ke, Ding, Liang, Chang, Ti-Cheng, Shao, Ying, Chiang, Jason, Mulder, Heather, Wang, Shuoguo, Shaw, Tim I., Wen, Ji, Hover, Laura, McLeod, Clay, Wang, Yong-Dong, Easton, John, Rusch, Michael, Dalton, James, Downing, James R., Ellison, David W., Zhang, Jinghui, Baker, Suzanne J., Wu, Gang
Publicado 2018

Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer

por Dong, Qian, Song, Nan, Qin, Na, Chen, Cheng, Li, Zhenghong, Sun, Xiaojun, Easton, John, Mulder, Heather, Plyler, Emily, Neale, Geoffrey, Walker, Emily, Li, Qian, Ma, Xiaotu, Chen, Xiang, Huang, I-Chan, Yasui, Yutaka, Ness, Kirsten K., Zhang, Jinghui, Hudson, Melissa M., Robison, Leslie L., Wang, Zhaoming
Publicado 2022

Distinct DNA methylation signatures associated with blood lipids as exposures or outcomes among survivors of childhood cancer: a report from the St. Jude lifetime cohort

por Dong, Qian, Chen, Cheng, Song, Nan, Qin, Na, Plonski, Noel-Marie, Finch, Emily R., Shelton, Kyla, Easton, John, Mulder, Heather, Plyer, Emily, Neale, Geoffrey, Walker, Emily, Li, Qian, Huang, I-Chan, Zhang, Jinghui, Wang, Hui, Hudson, Melissa M., Robison, Leslie L., Ness, Kirsten K., Wang, Zhaoming
Publicado 2023

Epigenetic Age in Peripheral Blood Among Children, Adolescent, and Adult Survivors of Childhood Cancer

por Plonski, Noel-Marie, Chen, Cheng, Dong, Qian, Qin, Na, Song, Nan, Parikh, Hemang M., Shelton, Kyla, Finch, Emily R., Easton, John, Mulder, Heather, Zhang, Jinghui, Neale, Geoffrey, Walker, Emily, Wang, Hui, Krull, Kevin, Ness, Kirsten K., Hudson, Melissa M., Robison, Leslie L., Li, Qian, Williams, AnnaLynn, Wang, Zhaoming
Publicado 2023

Persistent variations of blood DNA methylation associated with treatment exposures and risk for cardiometabolic outcomes in long-term survivors of childhood cancer in the St. Jude...

por Song, Nan, Hsu, Chia-Wei, Pan, Haitao, Zheng, Yinan, Hou, Lifang, Sim, Jin-ah, Li, Zhenghong, Mulder, Heather, Easton, John, Walker, Emily, Neale, Geoffrey, Wilson, Carmen L., Ness, Kirsten K., Krull, Kevin R., Srivastava, Deo Kumar, Yasui, Yutaka, Zhang, Jinghui, Hudson, Melissa M., Robison, Leslie L., Huang, I-Chan, Wang, Zhaoming
Publicado 2021

Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer

por Song, Nan, Sim, Jin-Ah, Dong, Qian, Zheng, Yinan, Hou, Lifang, Li, Zhenghong, Hsu, Chia-Wei, Pan, Haitao, Mulder, Heather, Easton, John, Walker, Emily, Neale, Geoffrey, Wilson, Carmen L., Ness, Kirsten K., Krull, Kevin R., Srivastava, Deo Kumar, Yasui, Yutaka, Zhang, Jinghui, Hudson, Melissa M., Robison, Leslie L., Huang, I-Chan, Wang, Zhaoming
Publicado 2022

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

por Brady, Samuel W., Liu, Yanling, Ma, Xiaotu, Gout, Alexander M., Hagiwara, Kohei, Zhou, Xin, Wang, Jian, Macias, Michael, Chen, Xiaolong, Easton, John, Mulder, Heather L., Rusch, Michael, Wang, Lu, Nakitandwe, Joy, Lei, Shaohua, Davis, Eric M., Naranjo, Arlene, Cheng, Cheng, Maris, John M., Downing, James R., Cheung, Nai-Kong V., Hogarty, Michael D., Dyer, Michael A., Zhang, Jinghui
Publicado 2020

Genomic landscape of pediatric adrenocortical tumors

por Pinto, Emilia M., Chen, Xiang, Easton, John, Finkelstein, David, Liu, Zhifa, Pounds, Stanley, Rodriguez-Galindo, Carlos, Lund, Troy C., Mardis, Elaine R., Wilson, Richard K., Boggs, Kristy, Yergeau, Donald, Cheng, Jinjun, Mulder, Heather L., Manne, Jayanthi, Jenkins, Jesse, Mastellaro, Maria J., Figueiredo, Bonald C., Dyer, Michael A., Pappo, Alberto, Zhang, Jinghui, Downing, James R., Ribeiro, Raul C., Zambetti, Gerard P.
Publicado 2015

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

por Murphy, Andrew J., Chen, Xiang, Pinto, Emilia M., Williams, Justin S., Clay, Michael R., Pounds, Stanley B., Cao, Xueyuan, Shi, Lei, Lin, Tong, Neale, Geoffrey, Morton, Christopher L., Woolard, Mary A., Mulder, Heather L., Gil, Hyea Jin, Rehg, Jerold E., Billups, Catherine A., Harlow, Matthew L., Dome, Jeffrey S., Houghton, Peter J., Easton, John, Zhang, Jinghui, George, Rani E., Zambetti, Gerard P., Davidoff, Andrew M.
Publicado 2019

The Genomic Landscape of Childhood and Adolescent Melanoma

por Lu, Charles, Zhang, Jinghui, Nagahawatte, Panduka, Easton, John, Lee, Seungjae, Liu, Zhifa, Ding, Li, Wyczalkowski, Matthew A, Valentine, Marcus, Navid, Fariba, Mulder, Heather, Tatevossian, Ruth G, Dalton, James, Davenport, James, Yin, Zhirong, Edmonson, Michael, Rusch, Michael, Wu, Gang, Li, Yongjin, Parker, Matthew, Hedlund, Erin, Shurtleff, Sheila, Raimondi, Susana, Bhavin, Vadodaria, Donald, Yergeau, Mardis, Elaine R, Wilson, Richard K, Evans, William E, Ellison, David W, Pounds, Stanley, Dyer, Michael, Downing, James R, Pappo, Alberto, Bahrami, Armita
Publicado 2015