Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data

por Cheng, Changde, Easton, John, Rosencrance, Celeste, Li, Yan, Ju, Bensheng, Williams, Justin, Mulder, Heather L, Pang, Yakun, Chen, Wenan, Chen, Xiang
Publicado 2019

Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor

por Flasch, Diane A., Chen, Xiaolong, Ju, Bensheng, Li, Xiaoyu, Dalton, James, Mulder, Heather L., Easton, John, Wang, Lu, Baker, Suzanne J., Chiang, Jason, Zhang, Jinghui
Publicado 2022

Association of Single-Nucleotide Variants in the Human Leukocyte Antigen and Other Loci With Childhood Hodgkin Lymphoma

por Chen, Cheng, Song, Nan, Dong, Qian, Sun, Xiaojun, Mulder, Heather L., Easton, John, Zhang, Jinghui, Yasui, Yutaka, Bhatia, Smita, Armstrong, Gregory T., Wang, Hui, Ness, Kirsten K., Hudson, Melissa M., Robison, Leslie L., Wang, Zhaoming
Publicado 2022

Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor

por Arunachalam, Sasi, Szlachta, Karol, Brady, Samuel W., Ma, Xiaotu, Ju, Bensheng, Shaner, Bridget, Mulder, Heather L., Easton, John, Raphael, Benjamin J., Myers, Matthew, Tinkle, Christopher, Allen, Sariah J., Orr, Brent A., Wetmore, Cynthia J., Baker, Suzanne J., Zhang, Jinghui
Publicado 2022

In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported

por Anekpuritanang, Tauangtham, Klairmont, Matthew M., Gradowski, Joel, Hagiwara, Kohei, Bailey, Nathanael G., Chandra, Pranil, Liu, Yiwei, Mulder, Heather L., Easton, John, Zhang, Jinghui, Martin, Michael G., Owczarczyk, Anna B., Dunlap, Jennifer B., Fan, Guang, Press, Richard D., Raess, Philipp W.
Publicado 2021

Dynamics of Age- versus Therapy-Related Clonal Hematopoiesis in Long-term Survivors of Pediatric Cancer

por Hagiwara, Kohei, Natarajan, Sivaraman, Wang, Zhaoming, Zubair, Haseeb, Mulder, Heather L., Dong, Li, Plyler, Emily M., Thimmaiah, Padma, Ma, Xiaotu, Ness, Kristen K., Li, Zhenghong, Mulrooney, Daniel A., Wilson, Carmen L., Yasui, Yutaka, Hudson, Melissa M., Easton, John, Robison, Leslie L., Zhang, Jinghui
Publicado 2023

Analysis of error profiles in deep next-generation sequencing data

por Ma, Xiaotu, Shao, Ying, Tian, Liqing, Flasch, Diane A., Mulder, Heather L., Edmonson, Michael N., Liu, Yu, Chen, Xiang, Newman, Scott, Nakitandwe, Joy, Li, Yongjin, Li, Benshang, Shen, Shuhong, Wang, Zhaoming, Shurtleff, Sheila, Robison, Leslie L., Levy, Shawn, Easton, John, Zhang, Jinghui
Publicado 2019

SequencErr: measuring and suppressing sequencer errors in next-generation sequencing data

por Davis, Eric M., Sun, Yu, Liu, Yanling, Kolekar, Pandurang, Shao, Ying, Szlachta, Karol, Mulder, Heather L., Ren, Dongren, Rice, Stephen V., Wang, Zhaoming, Nakitandwe, Joy, Gout, Alexander M., Shaner, Bridget, Hall, Salina, Robison, Leslie L., Pounds, Stanley, Klco, Jeffery M., Easton, John, Ma, Xiaotu
Publicado 2021

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

por Brady, Samuel W., Liu, Yanling, Ma, Xiaotu, Gout, Alexander M., Hagiwara, Kohei, Zhou, Xin, Wang, Jian, Macias, Michael, Chen, Xiaolong, Easton, John, Mulder, Heather L., Rusch, Michael, Wang, Lu, Nakitandwe, Joy, Lei, Shaohua, Davis, Eric M., Naranjo, Arlene, Cheng, Cheng, Maris, John M., Downing, James R., Cheung, Nai-Kong V., Hogarty, Michael D., Dyer, Michael A., Zhang, Jinghui
Publicado 2020

Genomic landscape of pediatric adrenocortical tumors

por Pinto, Emilia M., Chen, Xiang, Easton, John, Finkelstein, David, Liu, Zhifa, Pounds, Stanley, Rodriguez-Galindo, Carlos, Lund, Troy C., Mardis, Elaine R., Wilson, Richard K., Boggs, Kristy, Yergeau, Donald, Cheng, Jinjun, Mulder, Heather L., Manne, Jayanthi, Jenkins, Jesse, Mastellaro, Maria J., Figueiredo, Bonald C., Dyer, Michael A., Pappo, Alberto, Zhang, Jinghui, Downing, James R., Ribeiro, Raul C., Zambetti, Gerard P.
Publicado 2015

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor

por Murphy, Andrew J., Chen, Xiang, Pinto, Emilia M., Williams, Justin S., Clay, Michael R., Pounds, Stanley B., Cao, Xueyuan, Shi, Lei, Lin, Tong, Neale, Geoffrey, Morton, Christopher L., Woolard, Mary A., Mulder, Heather L., Gil, Hyea Jin, Rehg, Jerold E., Billups, Catherine A., Harlow, Matthew L., Dome, Jeffrey S., Houghton, Peter J., Easton, John, Zhang, Jinghui, George, Rani E., Zambetti, Gerard P., Davidoff, Andrew M.
Publicado 2019

Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication

por Liu, Yanling, Klein, Jonathon, Bajpai, Richa, Dong, Li, Tran, Quang, Kolekar, Pandurang, Smith, Jenny L., Ries, Rhonda E., Huang, Benjamin J., Wang, Yi-Cheng, Alonzo, Todd A., Tian, Liqing, Mulder, Heather L., Shaw, Timothy I., Ma, Jing, Walsh, Michael P., Song, Guangchun, Westover, Tamara, Autry, Robert J., Gout, Alexander M., Wheeler, David A., Wan, Shibiao, Wu, Gang, Yang, Jun J., Evans, William E., Loh, Mignon, Easton, John, Zhang, Jinghui, Klco, Jeffery M., Meshinchi, Soheil, Brown, Patrick A., Pruett-Miller, Shondra M., Ma, Xiaotu
Publicado 2023

Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators

por Fornerod, Maarten, Ma, Jing, Noort, Sanne, Liu, Yu, Walsh, Michael P., Shi, Lei, Nance, Stephanie, Liu, Yanling, Wang, Yuanyuan, Song, Guangchun, Lamprecht, Tamara, Easton, John, Mulder, Heather L., Yergeau, Donald, Myers, Jacquelyn, Kamens, Jennifer L., Obeng, Esther A., Pigazzi, Martina, Jarosova, Marie, Kelaidi, Charikleia, Polychronopoulou, Sophia, Lamba, Jatinder K., Baker, Sharyn D., Rubnitz, Jeffrey E., Reinhardt, Dirk, van den Heuvel-Eibrink, Marry M., Locatelli, Franco, Hasle, Henrik, Klco, Jeffery M., Downing, James R., Zhang, Jinghui, Pounds, Stanley, Zwaan, C. Michel, Gruber, Tanja A.
Publicado 2021

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

por Zhang, Jinghui, Wu, Gang, Miller, Claudia P., Tatevossian, Ruth G., Dalton, James D., Tang, Bo, Orisme, Wilda, Punchihewa, Chandanamali, Parker, Matthew, Qaddoumi, Ibrahim, Boop, Fredrick A., Lu, Charles, Kandoth, Cyriac, Ding, Li, Lee, Ryan, Huether, Robert, Chen, Xiang, Hedlund, Erin, Nagahawatte, Panduka, Rusch, Michael, Boggs, Kristy, Cheng, Jinjun, Becksfort, Jared, Ma, Jing, Song, Guangchun, Li, Yongjin, Wei, Lei, Wang, Jianmin, Shurtleff, Sheila, Easton, John, Zhao, David, Fulton, Robert S., Fulton, Lucinda L., Dooling, David J., Vadodaria, Bhavin, Mulder, Heather L., Tang, Chunlao, Ochoa, Kerri, Mullighan, Charles G., Gajjar, Amar, Kriwacki, Richard, Sheer, Denise, Gilbertson, Richard J., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Baker, Suzanne J., Ellison, David W.
Publicado 2013

C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma

por Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatte, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L, Becksford, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A, Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S, Fulton, Lucinda L, Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.
Publicado 2014

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

por Wu, Gang, Diaz, Alexander K, Paugh, Barbara S, Rankin, Sherri L, Ju, Bensheng, Li, Yongjin, Zhu, Xiaoyan, Qu, Chunxu, Chen, Xiang, Zhang, Junyuan, Easton, John, Edmonson, Michael, Ma, Xiaotu, Lu, Charles, Nagahawatte, Panduka, Hedlund, Erin, Rusch, Michael, Pounds, Stanley, Lin, Tong, Onar-Thomas, Arzu, Huether, Robert, Kriwacki, Richard, Parker, Matthew, Gupta, Pankaj, Becksfort, Jared, Wei, Lei, Mulder, Heather L, Boggs, Kristy, Vadodaria, Bhavin, Yergeau, Donald, Russell, Jake C, Ochoa, Kerri, Fulton, Robert S, Fulton, Lucinda L, Jones, Chris, Boop, Frederick A, Broniscer, Alberto, Wetmore, Cynthia, Gajjar, Amar, Ding, Li, Mardis, Elaine R, Wilson, Richard K, Taylor, Michael R, Downing, James R, Ellison, David W, Zhang, Jinghui, Baker, Suzanne J
Publicado 2014