Enhanced tumor-targeting selectivity by modulating bispecific antibody binding affinity and format valence

por Mazor, Yariv, Sachsenmeier, Kris F., Yang, Chunning, Hansen, Anna, Filderman, Jessica, Mulgrew, Kathy, Wu, Herren, Dall’Acqua, William F.
Publicado 2017

CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas

por Oberst, Michael D, Fuhrmann, Stacy, Mulgrew, Kathy, Amann, Maria, Cheng, Lily, Lutterbuese, Petra, Richman, Laura, Coats, Steve, Baeuerle, Patrick A, Hammond, Scott A
Publicado 2014

Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models

por Sitnikova, Suzanne Isabelle, Munnings-Tomes, Sophie, Galvani, Elena, Kentner, Stacy, Mulgrew, Kathy, Rands, Chris, España Agustí, Judit, Zhang, Tianhui, Ilieva, Kristina M, Rosignoli, Guglielmo, Ghadially, Hormas, Robinson, Matthew J, Slidel, Tim, Wilkinson, Robert W, Dovedi, Simon J
Publicado 2021

Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity

por Harper, James, Burke, Shannon, Travers, Jon, Rath, Nicola, Leinster, Andrew, Navarro, Christel, Franks, Ruth, Leyland, Rebecca, Mulgrew, Kathy, McGlinchey, Kelly, Brown, Lee, Dovedi, Simon J., Koopmann, Jens-Oliver, Durham, Nicholas M., Cheng, Xing, Jin, Hong, Eyles, Jim, Wilkinson, Robert W., Carroll, Danielle
Publicado 2021

Targeting CD73 in the tumor microenvironment with MEDI9447

por Hay, Carl M., Sult, Erin, Huang, Qihui, Mulgrew, Kathy, Fuhrmann, Stacy R., McGlinchey, Kelly A., Hammond, Scott A., Rothstein, Raymond, Rios-Doria, Jonathan, Poon, Edmund, Holoweckyj, Nick, Durham, Nicholas M., Leow, Ching Ching, Diedrich, Gundo, Damschroder, Melissa, Herbst, Ronald, Hollingsworth, Robert E., Sachsenmeier, Kris F.
Publicado 2016