Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin

por Foster, Benjamin M., Stolz, Paul, Mulholland, Christopher B., Montoya, Alex, Kramer, Holger, Bultmann, Sebastian, Bartke, Till
Publicado 2018

Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency

por Qin, Weihua, Ugur, Enes, Mulholland, Christopher B, Bultmann, Sebastian, Solovei, Irina, Modic, Miha, Smets, Martha, Wierer, Michael, Forné, Ignasi, Imhof, Axel, Cardoso, M Cristina, Leonhardt, Heinrich
Publicado 2021

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency

por Mulholland, Christopher B., Traube, Franziska R., Ugur, Enes, Parsa, Edris, Eckl, Eva-Maria, Schönung, Maximilian, Modic, Miha, Bartoschek, Michael D., Stolz, Paul, Ryan, Joel, Carell, Thomas, Leonhardt, Heinrich, Bultmann, Sebastian
Publicado 2020

A modular open platform for systematic functional studies under physiological conditions

por Mulholland, Christopher B., Smets, Martha, Schmidtmann, Elisabeth, Leidescher, Susanne, Markaki, Yolanda, Hofweber, Mario, Qin, Weihua, Manzo, Massimiliano, Kremmer, Elisabeth, Thanisch, Katharina, Bauer, Christina, Rombaut, Pascaline, Herzog, Franz, Leonhardt, Heinrich, Bultmann, Sebastian
Publicado 2015

TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation

por Stolz, Paul, Mantero, Angelo Salazar, Tvardovskiy, Andrey, Ugur, Enes, Wange, Lucas E, Mulholland, Christopher B, Cheng, Yuying, Wierer, Michael, Enard, Wolfgang, Schneider, Robert, Bartke, Till, Leonhardt, Heinrich, Elsässer, Simon J, Bultmann, Sebastian
Publicado 2022

Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger

por Hata, Keiichi, Kobayashi, Naohiro, Sugimura, Keita, Qin, Weihua, Haxholli, Deis, Chiba, Yoshie, Yoshimi, Sae, Hayashi, Gosuke, Onoda, Hiroki, Ikegami, Takahisa, Mulholland, Christopher B, Nishiyama, Atsuya, Nakanishi, Makoto, Leonhardt, Heinrich, Konuma, Tsuyoshi, Arita, Kyohei
Publicado 2022

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

por Gasparoni, Gilles, Bultmann, Sebastian, Lutsik, Pavlo, Kraus, Theo F. J., Sordon, Sabrina, Vlcek, Julia, Dietinger, Vanessa, Steinmaurer, Martina, Haider, Melanie, Mulholland, Christopher B., Arzberger, Thomas, Roeber, Sigrun, Riemenschneider, Matthias, Kretzschmar, Hans A., Giese, Armin, Leonhardt, Heinrich, Walter, Jörn
Publicado 2018

Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation

por Nishiyama, Atsuya, Mulholland, Christopher B., Bultmann, Sebastian, Kori, Satomi, Endo, Akinori, Saeki, Yasushi, Qin, Weihua, Trummer, Carina, Chiba, Yoshie, Yokoyama, Haruka, Kumamoto, Soichiro, Kawakami, Toru, Hojo, Hironobu, Nagae, Genta, Aburatani, Hiroyuki, Tanaka, Keiji, Arita, Kyohei, Leonhardt, Heinrich, Nakanishi, Makoto
Publicado 2020

Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals

por Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanashi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Publicado 2020

Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals

por Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanishi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Publicado 2020