Disease-associated patterns of acetylation stabilize tau fibril formation

por Li, Li, Nguyen, Binh, Mullapudi, Vishruth, Saelices, Lorena, Joachimiak, Lukasz A.
Publicado 2023

Seed-competent tau monomer initiates pathology in a tauopathy mouse model

por Mirbaha, Hilda, Chen, Dailu, Mullapudi, Vishruth, Terpack, Sandi Jo, White, Charles L., Joachimiak, Lukasz A., Diamond, Marc I.
Publicado 2022

Network of hotspot interactions cluster tau amyloid folds

por Mullapudi, Vishruth, Vaquer-Alicea, Jaime, Bommareddy, Vaibhav, Vega, Anthony R., Ryder, Bryan D., White, Charles L., Diamond, Marc. I., Joachimiak, Lukasz A.
Publicado 2023

DnaJC7 specifically regulates tau seeding

por Perez, Valerie A., Sanders, David W., Mendoza-Oliva, Ayde, Stopschinski, Barbara E., Mullapudi, Vishruth, White, Charles L, Joachimiak, Lukasz A., Diamond, Marc I.
Publicado 2023

DnaJC7 specifically regulates tau seeding

por Perez, Valerie Ann, Sanders, David W, Mendoza-Oliva, Ayde, Stopschinski, Barbara Elena, Mullapudi, Vishruth, White, Charles L, Joachimiak, Lukasz A, Diamond, Marc I
Publicado 2023

Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin

por Wydorski, Pawel M., Osipiuk, Jerzy, Lanham, Benjamin T., Tesar, Christine, Endres, Michael, Engle, Elizabeth, Jedrzejczak, Robert, Mullapudi, Vishruth, Michalska, Karolina, Fidelis, Krzysztof, Fushman, David, Joachimiak, Andrzej, Joachimiak, Lukasz A.
Publicado 2023

Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin

por Wydorski, Pawel M., Osipiuk, Jerzy, Lanham, Benjamin T., Tesar, Christine, Endres, Michael, Engle, Elizabeth, Jedrzejczak, Robert, Mullapudi, Vishruth, Michalska, Karolina, Fidelis, Krzysztof, Fushman, David, Joachimiak, Andrzej, Joachimiak, Lukasz A.
Publicado 2023

FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation

por Chen, Dailu, Bali, Sofia, Singh, Ruhar, Wosztyl, Aleksandra, Mullapudi, Vishruth, Vaquer-Alicea, Jaime, Jayan, Parvathy, Melhem, Shamiram, Seelaar, Harro, van Swieten, John C., Diamond, Marc I., Joachimiak, Lukasz A.
Publicado 2023