Abstract Regular Polytopes

por McMullen, Peter, Rota, G C, Schulte, Egon
Publicado 2002

Objective Supervised Machine Learning-Based Classification and Inference of Biological Neuronal Networks

por Barros, Michael Taynnan, Siljak, Harun, Mullen, Peter, Papadias, Constantinos, Hyttinen, Jari, Marchetti, Nicola
Publicado 2022

The role of HDAC2 in chromatin remodelling and response to chemotherapy in ovarian cancer

por Huang, Rui, Langdon, Simon P, Tse, Matthew, Mullen, Peter, Um, In Hwa, Faratian, Dana, Harrison, David J
Publicado 2015

A signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT

por Bown, James L., Shovman, Mark, Robertson, Paul, Boiko, Andrei, Goltsov, Alexey, Mullen, Peter, Harrison, David J.
Publicado 2016

Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031

por Sarr, Awa, Bré, Jennifer, Um, In Hwa, Chan, Tsz Huen, Mullen, Peter, Harrison, David J., Reynolds, Paul A.
Publicado 2019

Sprouty 2 Is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy

por Faratian, Dana, Sims, Andrew H., Mullen, Peter, Kay, Charlene, Um, InHwa, Langdon, Simon P., Harrison, David J.
Publicado 2011

Model-based global sensitivity analysis as applied to identification of anti-cancer drug targets and biomarkers of drug resistance in the ErbB2/3 network

por Lebedeva, Galina, Sorokin, Anatoly, Faratian, Dana, Mullen, Peter, Goltsov, Alexey, Langdon, Simon P., Harrison, David J., Goryanin, Igor
Publicado 2012

Diversity of Matriptase Expression Level and Function in Breast Cancer

por Welman, Arkadiusz, Sproul, Duncan, Mullen, Peter, Muir, Morwenna, Kinnaird, Andrew R., Harrison, David J., Faratian, Dana, Brunton, Valerie G., Frame, Margaret C.
Publicado 2012

Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model

por Moore, Kate M., Cerqueira, Vera, MacLeod, Kenneth G., Mullen, Peter, Hayward, Richard L., Green, Simon, Harrison, David J., Cameron, David A., Langdon, Simon P.
Publicado 2022

Overcoming intratumoural heterogeneity for reproducible molecular risk stratification: a case study in advanced kidney cancer

por Lubbock, Alexander L. R., Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Mullen, Peter, O’Donnell, Marie, Powles, Thomas, Harrison, David J., Overton, Ian M.
Publicado 2017

The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent

por Bré, Jennifer, Dickson, Alison L., Read, Oliver J., Zhang, Ying, McKissock, Fiona G., Mullen, Peter, Tang, Peijun, Zickuhr, Greice M., Czekster, Clarissa M., Harrison, David J.
Publicado 2023

Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models

por Martínez-Pérez, Carlos, Ward, Carol, Turnbull, Arran K, Mullen, Peter, Cook, Graeme, Meehan, James, Jarman, Edward J, Thomson, Patrick IT, Campbell, Colin J, McPhail, Donald, Harrison, David J, Langdon, Simon P
Publicado 2016

Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death

por Pandyra, Aleksandra A., Mullen, Peter J., Goard, Carolyn A., Ericson, Elke, Sharma, Piyush, Kalkat, Manpreet, Yu, Rosemary, Pong, Janice T., Brown, Kevin R., Hart, Traver, Gebbia, Marinella, Lang, Karl S., Giaever, Guri, Nislow, Corey, Moffat, Jason, Penn, Linda Z.
Publicado 2015

An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

por Longo, Joseph, Mullen, Peter J., Yu, Rosemary, van Leeuwen, Jenna E., Masoomian, Mehdi, Woon, Dixon T.S., Wang, Yuzhuo, Chen, Eric X., Hamilton, Robert J., Sweet, Joan M., van der Kwast, Theodorus H., Fleshner, Neil E., Penn, Linda Z.
Publicado 2019

SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition

por Mullen, Peter J., Garcia, Gustavo, Purkayastha, Arunima, Matulionis, Nedas, Schmid, Ernst W., Momcilovic, Milica, Sen, Chandani, Langerman, Justin, Ramaiah, Arunachalam, Shackelford, David B., Damoiseaux, Robert, French, Samuel W., Plath, Kathrin, Gomperts, Brigitte N., Arumugaswami, Vaithilingaraja, Christofk, Heather R.
Publicado 2021

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

por Meehan, James, Ward, Carol, Turnbull, Arran, Bukowski-Wills, Jimi, Finch, Andrew J., Jarman, Edward J., Xintaropoulou, Chrysi, Martinez-Perez, Carlos, Gray, Mark, Pearson, Matthew, Mullen, Peter, Supuran, Claudiu T., Carta, Fabrizio, Harrison, David J., Kunkler, Ian H., Langdon, Simon P.
Publicado 2017

A pilot window-of-opportunity study of preoperative fluvastatin in localized prostate cancer

por Longo, Joseph, Hamilton, Robert J., Masoomian, Mehdi, Khurram, Najia, Branchard, Emily, Mullen, Peter J., Elbaz, Mohamad, Hersey, Karen, Chadwick, Dianne, Ghai, Sangeet, Andrews, David W., Chen, Eric X., van der Kwast, Theodorus H., Fleshner, Neil E., Penn, Linda Z.
Publicado 2020

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

por Ward, Carol, Meehan, James, Mullen, Peter, Supuran, Claudiu, Dixon, J. Michael, Thomas, Jeremy S., Winum, Jean-Yves, Lambin, Philippe, Dubois, Ludwig, Pavathaneni, Nanda-Kumar, Jarman, Edward J., Renshaw, Lorna, Um, InHwa, Kay, Charlene, Harrison, David J., Kunkler, Ian H., Langdon, Simon P.
Publicado 2015

Carbonic Anhydrase 9 Expression Increases with Vascular Endothelial Growth Factor–Targeted Therapy and Is Predictive of Outcome in Metastatic Clear Cell Renal Cancer

por Stewart, Grant D., O’Mahony, Fiach C., Laird, Alexander, Rashid, Sukaina, Martin, Sarah A., Eory, Lel, Lubbock, Alexander L.R., Nanda, Jyoti, O’Donnell, Marie, Mackay, Alan, Mullen, Peter, McNeill, S. Alan, Riddick, Antony C.P., Aitchison, Michael, Berney, Daniel, Bex, Axel, Overton, Ian M., Harrison, David J., Powles, Thomas
Publicado 2014

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

por Halbrook, Christopher J., Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A., McCarthy, Amy, Steele, Nina G., Kerk, Samuel A., Hong, Hanna S., Lin, Lin, Law, Fiona V., Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K., Singh, Rima, Nelson, Barbara S., Van Den Bergh, Fran, Krall, Abigail S., Mullen, Peter J., Zhang, Li, Batra, Sandeep, Morton, Jennifer P., Stanger, Ben Z., Christofk, Heather R., Digman, Michelle A., Beard, Daniel A., Viale, Andrea, Zhang, Ji, Crawford, Howard C., Pasca di Magliano, Marina, Jorgensen, Claus, Lyssiotis, Costas A.
Publicado 2022