mRNA processing in mutant zebrafish lines generated by chemical and CRISPR-mediated mutagenesis produces unexpected transcripts that escape nonsense-mediated decay

por Anderson, Jennifer L., Mulligan, Timothy S., Shen, Meng-Chieh, Wang, Hui, Scahill, Catherine M., Tan, Frederick J., Du, Shao J., Busch-Nentwich, Elisabeth M., Farber, Steven A.
Publicado 2017

Multiplexed CRISPR/Cas9 Targeting of Genes Implicated in Retinal Regeneration and Degeneration

por Unal Eroglu, Arife, Mulligan, Timothy S., Zhang, Liyun, White, David T., Sengupta, Sumitra, Nie, Cathy, Lu, Noela Y., Qian, Jiang, Xu, Lisha, Pei, Wuhong, Burgess, Shawn M., Saxena, Meera T., Mumm, Jeff S.
Publicado 2018

A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screening

por Rich, Michelle H, Sharrock, Abigail V, Mulligan, Timothy S, Matthews, Frazer, Brown, Alistair S, Lee-Harwood, Hannah R, Williams, Elsie M, Copp, Janine N, Little, Rory F, Francis, Jenni JB, Horvat, Claire N, Stevenson, Luke J, Owen, Jeremy G, Saxena, Meera T, Mumm, Jeff S, Ackerley, David F
Publicado 2023

NTR 2.0: a rationally-engineered prodrug converting enzyme with substantially enhanced efficacy for targeted cell ablation

por Sharrock, Abigail V., Mulligan, Timothy S., Hall, Kelsi R., Williams, Elsie M., White, David T., Zhang, Liyun, Emmerich, Kevin, Matthews, Frazer, Nimmagadda, Saumya, Washington, Selena, Le, Katherine D., Meir-Levi, Danielle, Cox, Olivia L., Saxena, Meera T., Calof, Anne L., Lopez-Burks, Martha E., Lander, Arthur D., Ding, Ding, Ji, Hongkai, Ackerley, David F., Mumm, Jeff S.
Publicado 2022

Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa

por Zhang, Liyun, Chen, Conan, Fu, Jie, Lilley, Brendan, Berlinicke, Cynthia, Hansen, Baranda, Ding, Ding, Wang, Guohua, Wang, Tao, Shou, Daniel, Ye, Ying, Mulligan, Timothy, Emmerich, Kevin, Saxena, Meera T, Hall, Kelsi R, Sharrock, Abigail V, Brandon, Carlene, Park, Hyejin, Kam, Tae-In, Dawson, Valina L, Dawson, Ted M, Shim, Joong Sup, Hanes, Justin, Ji, Hongkai, Liu, Jun O, Qian, Jiang, Ackerley, David F, Rohrer, Baerbel, Zack, Donald J, Mumm, Jeff S
Publicado 2021