Pediatric acute lymphoblastic leukemia

por Inaba, Hiroto, Mullighan, Charles G.
Publicado 2020

Biologic and Therapeutic Implications of Genomic Alterations in Acute Lymphoblastic Leukemia

por Iacobucci, Ilaria, Kimura, Shunsuke, Mullighan, Charles G.
Publicado 2021

Integration of Next-Generation Sequencing to Treat Acute Lymphoblastic Leukemia with Targetable Lesions: The St. Jude Children’s Research Hospital Approach

por Inaba, Hiroto, Azzato, Elizabeth M., Mullighan, Charles G.
Publicado 2017

Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis

por Welsh, Seth J., Churchman, Michelle L., Togni, Marco, Mullighan, Charles G., Hagman, James
Publicado 2017

Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study

por Annells, Margaret F, Hart, Prue H, Mullighan, Charles G, Heatley, Susan L, Robinson, Jeffrey S, McDonald, Helen M
Publicado 2005

RNAseqCNV: analysis of large-scale copy number variations from RNA-seq data

por Bařinka, Jan, Hu, Zunsong, Wang, Lu, Wheeler, David A., Rahbarinia, Delaram, McLeod, Clay, Gu, Zhaohui, Mullighan, Charles G.
Publicado 2022

Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome

por Fabbri, Giulia, Khiabanian, Hossein, Holmes, Antony B., Wang, Jiguang, Messina, Monica, Mullighan, Charles G., Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo
Publicado 2013

The PAX5‐JAK2 translocation acts as dual‐hit mutation that promotes aggressive B‐cell leukemia via nuclear STAT5 activation

por Jurado, Sabine, Fedl, Anna S, Jaritz, Markus, Kostanova‐Poliakova, Daniela, Malin, Stephen G, Mullighan, Charles G, Strehl, Sabine, Fischer, Maria, Busslinger, Meinrad
Publicado 2022

Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential

por Treanor, Louise M., Zhou, Sheng, Janke, Laura, Churchman, Michelle L., Ma, Zhijun, Lu, Taihe, Chen, Shann-Ching, Mullighan, Charles G., Sorrentino, Brian P.
Publicado 2014

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

por Dutta, Ankit K., Fink, J. Lynn, Grady, John P., Morgan, Gareth J., Mullighan, Charles G., To, Luen B., Hewett, Duncan R., Zannettino, Andrew C. W.
Publicado 2018

VpreB surrogate light chain expression in B-lineage ALL: a report from the Children’s Oncology Group

por Winter, Stuart S., McCaustland, Amanda, Qu, Chunxu, Simeona, No’eau, Heerema, Nyla A., Carroll, Andrew J., Wood, Brent L., Gheorghe, Gabriela, Mullighan, Charles G., Wilson, Bridget S.
Publicado 2022

The landscape of coding RNA editing events in pediatric cancer

por Wen, Ji, Rusch, Michael, Brady, Samuel W., Shao, Ying, Edmonson, Michael N., Shaw, Timothy I., Powers, Brent B., Tian, Liqing, Easton, John, Mullighan, Charles G., Gruber, Tanja, Ellison, David, Zhang, Jinghui
Publicado 2021

G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL

por Iacobucci, Ilaria, Fukano, Reiji, D. Friske, Jake, Qu, Chunxu, Janke, Laura J., Zhao, Yaqi, Baviskar, Pradyuamna, A. Backhaus, Emily, Chockley, Peter, Seth, Aman, Laird, A. Douglas, Advani, Anjali S., Mullighan, Charles G.
Publicado 2022

Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

por Sharma, Nitesh D., Nickl, Christian K., Kang, Huining, Ornatowski, Wojciech, Brown, Roger, Ness, Scott A., Loh, Mignon L., Mullighan, Charles G., Winter, Stuart S., Hunger, Stephen P., Cannon, Judy L., Matlawska‐Wasowska, Ksenia
Publicado 2019

CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors

por Lo, Yu-Chen, Keyes, Timothy J., Jager, Astraea, Sarno, Jolanda, Domizi, Pablo, Majeti, Ravindra, Sakamoto, Kathleen M., Lacayo, Norman, Mullighan, Charles G., Waters, Jeffrey, Sahaf, Bita, Bendall, Sean C., Davis, Kara L.
Publicado 2022

The genomic landscape of pediatric myelodysplastic syndromes

por Schwartz, Jason R., Ma, Jing, Lamprecht, Tamara, Walsh, Michael, Wang, Shuoguo, Bryant, Victoria, Song, Guangchun, Wu, Gang, Easton, John, Kesserwan, Chimene, Nichols, Kim E., Mullighan, Charles G., Ribeiro, Raul C., Klco, Jeffery M.
Publicado 2017

Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia

por Niswander, Lisa M., Loftus, Joseph P, Lainey, Élodie, Caye-Eude, Aurélie, Pondrom, Morgane, Hottman, David A., Iacobucci, Ilaria, Mullighan, Charles G., Jain, Nitin, Konopleva, Marina, Cavé, Hélène, Baruchel, André, Rohrlich, Pierre S., Tasian, Sarah K.
Publicado 2021

Novel UHRF1-MYC Axis in Acute Lymphoblastic Leukemia

por Park, Soyoung, Sater, Ali H. Abdel, Fahrmann, Johannes F., Irajizad, Ehsan, Cai, Yining, Katayama, Hiroyuki, Vykoukal, Jody, Kobayashi, Makoto, Dennison, Jennifer B., Garcia-Manero, Guillermo, Mullighan, Charles G., Gu, Zhaohui, Konopleva, Marina, Hanash, Samir
Publicado 2022

New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment

por Cheung, Laurence C., Tickner, Jennifer, Hughes, Anastasia M., Skut, Patrycja, Howlett, Meegan, Foley, Bree, Oommen, Joyce, Wells, Julia E., He, Bo, Singh, Sajla, Chua, Grace-Alyssa, Ford, Jette, Mullighan, Charles G., Kotecha, Rishi S., Kees, Ursula R.
Publicado 2018

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment

por Tran, Thai Hoa, Nguyen, Jonathan V., Stecula, Adrian, Akutagawa, Jon, Moorman, Anthony V., Braun, Benjamin S., Sali, Andrej, Mullighan, Charles G., Shah, Neil P., Dai, Yunfeng, Devidas, Meenakshi, Roberts, Kathryn G., Smith, Catherine C., Loh, Mignon L.
Publicado 2021