Is TIMP-1 immunoreactivity alone or in combination with other markers a predictor of benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial?

por Munro, Alison F, Bartels, Annette, Balslev, Eva, Twelves, Christopher J, Cameron, David A, Brünner, Nils, Bartlett, John MS
Publicado 2013

High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathways

por Warchal, Scott J., Dawson, John C., Shepherd, Emelie, Munro, Alison F., Hughes, Rebecca E., Makda, Ashraff, Carragher, Neil O.
Publicado 2020

High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel...

por Hughes, Rebecca E., Elliott, Richard J. R., Munro, Alison F., Makda, Ashraff, O’Neill, J. Robert, Hupp, Ted, Carragher, Neil O.
Publicado 2020

A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials

por Spears, Melanie, Yousif, Fouad, Lyttle, Nicola, Boutros, Paul C., Munro, Alison F., Twelves, Chris, Pritchard, Kathleen I., Levine, Mark N., Shepherd, Lois, Bartlett, John MS.
Publicado 2015

Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts

por Rifai, Olivia M, O’Shaughnessy, Judi, Dando, Owen R, Munro, Alison F, Sewell, Michael D E, Abrahams, Sharon, Waldron, Fergal M, Sibley, Christopher R, Gregory, Jenna M
Publicado 2023

Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes

por Hughes, Rebecca E., Elliott, Richard J. R., Li, Xiaodun, Munro, Alison F., Makda, Ashraff, Carter, Roderick N., Morton, Nicholas M., Fujihara, Kenji, Clemons, Nicholas J., Fitzgerald, Rebecca, O’Neill, J. Robert, Hupp, Ted, Carragher, Neil O.
Publicado 2022

Rapid Discovery and Structure–Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity...

por Fraser, Craig, Dawson, John C., Dowling, Reece, Houston, Douglas R., Weiss, Jason T., Munro, Alison F., Muir, Morwenna, Harrington, Lea, Webster, Scott P., Frame, Margaret C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2016

Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: comparison of gene expression profiling approaches

por Turnbull, Arran K., Selli, Cigdem, Martinez-Perez, Carlos, Fernando, Anu, Renshaw, Lorna, Keys, Jane, Figueroa, Jonine D., He, Xiaping, Tanioka, Maki, Munro, Alison F., Murphy, Lee, Fawkes, Angie, Clark, Richard, Coutts, Audrey, Perou, Charles M., Carey, Lisa A., Dixon, J. Michael, Sims, Andrew H.
Publicado 2020

Crosstalk with lung fibroblasts shapes the growth and therapeutic response of mesothelioma cells

por Chrisochoidou, Yakinthi, Roy, Rajat, Farahmand, Pooyeh, Gonzalez, Guadalupe, Doig, Jennifer, Krasny, Lukas, Rimmer, Ella F., Willis, Anne E, MacFarlane, Marion, Huang, Paul H., Carragher, Neil O., Munro, Alison F., Murphy, Daniel J., Veselkov, Kirill, Seckl, Michael J., Moffatt, Miriam F., Cookson, William O. C., Pardo, Olivier E.
Publicado 2023

A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability

por Temps, Carolin, Lietha, Daniel, Webb, Emily R., Li, Xue-Feng, Dawson, John C., Muir, Morwenna, Macleod, Kenneth G., Valero, Teresa, Munro, Alison F., Contreras-Montoya, Rafael, Luque-Ortega, Juan R., Fraser, Craig, Beetham, Henry, Schoenherr, Christina, Lopalco, Maria, Arends, Mark J., Frame, Margaret C., Qian, Bin-Zhi, Brunton, Valerie G., Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2021