mTOR activates the VPS34–UVRAG complex to regulate autolysosomal tubulation and cell survival

por Munson, Michael J, Allen, George FG, Toth, Rachel, Campbell, David G, Lucocq, John M, Ganley, Ian G
Publicado 2015

GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling

por Stretton, Clare, Hoffmann, Thorsten M., Munson, Michael J., Prescott, Alan, Taylor, Peter M., Ganley, Ian G., Hundal, Harinder S.
Publicado 2015

SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin‐2

por Søreng, Kristiane, Munson, Michael J, Lamb, Christopher A, Bjørndal, Gunnveig T, Pankiv, Serhiy, Carlsson, Sven R, Tooze, Sharon A, Simonsen, Anne
Publicado 2018

GAK and PRKCD kinases regulate basal mitophagy

por Munson, Michael J., Mathai, Benan J., Ng, Matthew Yoke Wui, Trachsel-Moncho, Laura, de la Ballina, Laura R., Simonsen, Anne
Publicado 2022

A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery

por Munson, Michael J., O’Driscoll, Gwen, Silva, Andreia M., Lázaro-Ibáñez, Elisa, Gallud, Audrey, Wilson, John T., Collén, Anna, Esbjörner, Elin K., Sabirsh, Alan
Publicado 2021

The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics

por Ng, Matthew Yoke Wui, Charsou, Chara, Lapao, Ana, Singh, Sakshi, Trachsel-Moncho, Laura, Schultz, Sebastian W., Nakken, Sigve, Munson, Michael J., Simonsen, Anne
Publicado 2022

mito-QC illuminates mitophagy and mitochondrial architecture in vivo

por McWilliams, Thomas G., Prescott, Alan R., Allen, George F.G., Tamjar, Jevgenia, Munson, Michael J., Thomson, Calum, Muqit, Miratul M.K., Ganley, Ian G.
Publicado 2016

Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III pho...

por Bago, Ruzica, Malik, Nazma, Munson, Michael J., Prescott, Alan R., Davies, Paul, Sommer, Eeva, Shpiro, Natalia, Ward, Richard, Cross, Darren, Ganley, Ian G., Alessi, Dario R.
Publicado 2014

TECPR1 is activated by damage‐induced sphingomyelin exposure to mediate noncanonical autophagy

por Kaur, Namrita, de la Ballina, Laura Rodriguez, Haukaas, Håvard Styrkestad, Torgersen, Maria Lyngaas, Radulovic, Maja, Munson, Michael J, Sabirsh, Alan, Stenmark, Harald, Simonsen, Anne, Carlsson, Sven R, Lystad, Alf Håkon
Publicado 2023

ESCRT-mediated phagophore sealing during mitophagy

por Zhen, Yan, Spangenberg, Hélène, Munson, Michael J., Brech, Andreas, Schink, Kay O., Tan, Kia-Wee, Sørensen, Vigdis, Wenzel, Eva Maria, Radulovic, Maja, Engedal, Nikolai, Simonsen, Anne, Raiborg, Camilla, Stenmark, Harald
Publicado 2019

GAK and PRKCD are positive regulators of PRKN-independent mitophagy

por Munson, Michael J., Mathai, Benan J., Ng, Matthew Yoke Wui, Trachsel-Moncho, Laura, de la Ballina, Laura R., Schultz, Sebastian W., Aman, Yahyah, Lystad, Alf H., Singh, Sakshi, Singh, Sachin, Wesche, Jørgen, Fang, Evandro F., Simonsen, Anne
Publicado 2021

Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides

por Bost, Jeremy P., Ojansivu, Miina, Munson, Michael J., Wesén, Emelie, Gallud, Audrey, Gupta, Dhanu, Gustafsson, Oskar, Saher, Osama, Rädler, Julia, Higgins, Stuart G., Lehto, Taavi, Holme, Margaret N., Dahlén, Anders, Engkvist, Ola, Strömstedt, Per-Erik, Andersson, Shalini, Edvard Smith, C. I., Stevens, Molly M., Esbjörner, Elin K., Collén, Anna, El Andaloussi, Samir
Publicado 2022