Cytoplasmic superoxide radical: a possible contributing factor to intracellular Aβ oligomerization in Alzheimer disease

por Murakami, Kazuma, Shimizu, Takahiko
Publicado 2012

Three Structural Features of Functional Food Components and Herbal Medicine with Amyloid β42 Anti-Aggregation Properties

por Murakami, Kazuma, Irie, Kazuhiro
Publicado 2019

Formation of the 42-mer Amyloid β Radical and the Therapeutic Role of Superoxide Dismutase in Alzheimer's Disease

por Murakami, Kazuma, Shimizu, Takahiko, Irie, Kazuhiro
Publicado 2011

Aptamers targeting amyloidogenic proteins and their emerging role in neurodegenerative diseases

por Murakami, Kazuma, Izuo, Naotaka, Bitan, Gal
Publicado 2021

RNA Aptamers Generated against Oligomeric Aβ40 Recognize Common Amyloid Aptatopes with Low Specificity but High Sensitivity

por Rahimi, Farid, Murakami, Kazuma, Summers, Jamie L., Chen, Chi-Hong B., Bitan, Gal
Publicado 2009

A screen for sleep and starvation resistance identifies a wake-promoting role for the auxiliary channel unc79

por Murakami, Kazuma, Palermo, Justin, Stanhope, Bethany A, Gibbs, Allen G, Keene, Alex C
Publicado 2021

Evaluation of Toxic Amyloid β42 Oligomers in Rat Primary Cerebral Cortex Cells and Human iPS-derived Neurons Treated with 10-Me-Aplog-1, a New PKC Activator

por Murakami, Kazuma, Yoshimura, Mayuko, Nakagawa, Shota, Kume, Toshiaki, Kondo, Takayuki, Inoue, Haruhisa, Irie, Kazuhiro
Publicado 2020

Detection of Amyloid β Oligomers with RNA Aptamers in App(NL-G-F/NL-G-F) Mice: A Model of Arctic Alzheimer’s Disease

por Obata, Yayoi, Murakami, Kazuma, Kawase, Taiji, Hirose, Kenji, Izuo, Naotaka, Shimizu, Takahiko, Irie, Kazuhiro
Publicado 2020

A Toxic Conformer of Aβ42 with a Turn at 22–23 is a Novel Therapeutic Target for Alzheimer’s Disease

por Izuo, Naotaka, Kasahara, Chihiro, Murakami, Kazuma, Kume, Toshiaki, Maeda, Masahiro, Irie, Kazuhiro, Yokote, Koutaro, Shimizu, Takahiko
Publicado 2017

Synthetic and biochemical studies on the effect of persulfidation on disulfide dimer models of amyloid β42 at position 35 in Alzheimer's etiology

por Murakami, Kazuma, Kato, Haruka, Hanaki, Mizuho, Monobe, Yoko, Akagi, Ken-ichi, Kawase, Taiji, Hirose, Kenji, Irie, Kazuhiro
Publicado 2020

Lysine-targeting inhibition of amyloid β oligomerization by a green perilla-derived metastable chalcone in vitro and in vivo

por Murakami, Kazuma, Sakaguchi, Yoshiki, Taniwa, Kota, Izuo, Naotaka, Hanaki, Mizuho, Kawase, Taiji, Hirose, Kenji, Shimizu, Takahiko, Irie, Kazuhiro
Publicado 2022

E22Δ Mutation in Amyloid β-Protein Promotes β-Sheet Transformation, Radical Production, and Synaptotoxicity, But Not Neurotoxicity

por Suzuki, Takayuki, Murakami, Kazuma, Izuo, Naotaka, Kume, Toshiaki, Akaike, Akinori, Nagata, Tetsu, Nishizaki, Tomoyuki, Tomiyama, Takami, Takuma, Hiroshi, Mori, Hiroshi, Irie, Kazuhiro
Publicado 2010

Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques

por Kageyama, Yusuke, Saito, Atsushi, Pletnikova, Olga, Rudow, Gay L., Irie, Yumi, An, Yang, Murakami, Kazuma, Irie, Kazuhiro, Resnick, Susan M., Fowler, David R., Martin, Lee J., Troncoso, Juan C.
Publicado 2018

Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer’s disease diagnosis

por Murakami, Kazuma, Tokuda, Maki, Suzuki, Takashi, Irie, Yumi, Hanaki, Mizuho, Izuo, Naotaka, Monobe, Yoko, Akagi, Ken-ichi, Ishii, Ryotaro, Tatebe, Harutsugu, Tokuda, Takahiko, Maeda, Masahiro, Kume, Toshiaki, Shimizu, Takahiko, Irie, Kazuhiro
Publicado 2016

Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

por Tsukada, Kento, Shinki, Shono, Kaneko, Akiho, Murakami, Kazuma, Irie, Kazuhiro, Murai, Masatoshi, Miyoshi, Hideto, Dan, Shingo, Kawaji, Kumi, Hayashi, Hironori, Kodama, Eiichi N., Hori, Aki, Salim, Emil, Kuraishi, Takayuki, Hirata, Naoya, Kanda, Yasunari, Asai, Teigo
Publicado 2020