Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability

por Cai, Chao-Yun, Teng, Qiu-Xu, Murakami, Megumi, Ambudkar, Suresh V., Chen, Zhe-Sheng, Korlipara, Vijaya L.
Publicado 2023

Central mucoepidermoid carcinoma of the maxilla developing from a calcifying odontogenic cyst: A rare case report

por Isshiki‐Murakami, Megumi, Tachinami, Hidetake, Tomihara, Kei, Noguchi, Akira, Sekido, Katsuhisa, Imaue, Shuichi, Fujiwara, Kumiko, Imura, Johji, Noguchi, Makoto
Publicado 2021

Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein

por Sajid, Andaleeb, Lusvarghi, Sabrina, Murakami, Megumi, Chufan, Eduardo E., Abel, Biebele, Gottesman, Michael M., Durell, Stewart R., Ambudkar, Suresh V.
Publicado 2020

Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

por Wu, Chung-Pu, Murakami, Megumi, Li, Yen-Ching, Huang, Yang-Hui, Chang, Yu-Tzu, Hung, Tai-Ho, Wu, Yu-Shan, Ambudkar, Suresh V.
Publicado 2023

Branebrutinib (BMS-986195), a Bruton’s Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents

por Wu, Chung-Pu, Murakami, Megumi, Wu, Yu-Shan, Chi, Ya-Chen, Hsiao, Sung-Han, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh V.
Publicado 2021

Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells

por Li, Yan-Qing, Murakami, Megumi, Huang, Yang-Hui, Hung, Tai-Ho, Wang, Shun-Ping, Wu, Yu-Shan, Ambudkar, Suresh V., Wu, Chung-Pu
Publicado 2022

P-glycoprotein Mediates Resistance to the Anaplastic Lymphoma Kinase Inhiitor Ensartinib in Cancer Cells

por Wu, Chung-Pu, Hung, Cheng-Yu, Murakami, Megumi, Wu, Yu-Shan, Lin, Chun-Ling, Huang, Yang-Hui, Hung, Tai-Ho, Yu, Jau-Song, Ambudkar, Suresh V.
Publicado 2022

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines

por Wu, Chung-Pu, Hung, Cheng-Yu, Hsieh, Ya-Ju, Murakami, Megumi, Huang, Yang-Hui, Su, Tsung-Yao, Hung, Tai-Ho, Yu, Jau-Song, Wu, Yu-Shan, Ambudkar, Suresh V.
Publicado 2023

Infliximab Inhibits Colitis Associated Cancer in Model Mice by Downregulating Genes Associated with Mast Cells and Decreasing Their Accumulation

por Wang, Dan-Yang, Ohnuma, Shinobu, Suzuki, Hideyuki, Ishida, Masaharu, Ishii, Kentaro, Hirosawa, Takashi, Hirashima, Tomoaki, Murakami, Megumi, Kobayashi, Minoru, Kudoh, Katsuyoshi, Haneda, Sho, Musha, Hiroaki, Naitoh, Takeshi, Unno, Michiaki
Publicado 2023

Furmonertinib, a Third-Generation EGFR Tyrosine Kinase Inhibitor, Overcomes Multidrug Resistance through Inhibiting ABCB1 and ABCG2 in Cancer Cells

por Wu, Chung-Pu, Li, Yen-Ching, Murakami, Megumi, Hsiao, Sung-Han, Lee, Yun-Chieh, Huang, Yang-Hui, Chang, Yu-Tzu, Hung, Tai-Ho, Wu, Yu-Shan, Ambudkar, Suresh V.
Publicado 2023

A Phenylfurocoumarin Derivative Reverses ABCG2-Mediated Multidrug Resistance In Vitro and In Vivo

por Kokubo, Shoji, Ohnuma, Shinobu, Murakami, Megumi, Kikuchi, Haruhisa, Funayama, Shota, Suzuki, Hideyuki, Kajiwara, Taiki, Yamamura, Akihiro, Karasawa, Hideaki, Sugisawa, Norihiko, Ohsawa, Kosuke, Kano, Kuniyuki, Aoki, Junken, Doi, Takayuki, Naitoh, Takeshi, Ambudkar, Suresh V., Unno, Michiaki
Publicado 2021