Cyclin-dependent kinase inhibitors in brain cancer: current state and future directions

por Juric, Viktorija, Murphy, Brona
Publicado 2020

Inducing cell death in Glioblastoma

por Tappuni, Shahed, Noonan, Janis, Murphy, Brona
Publicado 2015

Targeting the apoptosis pathway to treat tumours of the paediatric nervous system

por Fitzgerald, Marie-Claire, O’Halloran, Philip J., Connolly, Niamh M. C., Murphy, Brona M.
Publicado 2022

The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c

por Murphy, Brona M., O'Neill, Amanda J., Adrain, Colin, Watson, R. William G., Martin, Seamus J.
Publicado 2003

Phenotypic selection through cell death: stochastic modelling of O-6-methylguanine-DNA methyltransferase dynamics

por Lasri, Ayoub, Juric, Viktorija, Verreault, Maité, Bielle, Franck, Idbaih, Ahmed, Kel, Alexander, Murphy, Brona, Sturrock, Marc
Publicado 2020

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

por Juric, Viktorija, Düssmann, Heiko, Lamfers, Martine L. M., Prehn, Jochen H. M., Rehm, Markus, Murphy, Brona M.
Publicado 2021

Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide

por Weyhenmeyer, Birgit C., Noonan, Janis, Würstle, Maximilian L., Lincoln, Frank A., Johnston, Grainne, Rehm, Markus, Murphy, Brona M.
Publicado 2016

System-based approaches as prognostic tools for glioblastoma

por Salvucci, Manuela, Zakaria, Zaitun, Carberry, Steven, Tivnan, Amanda, Seifert, Volker, Kögel, Donat, Murphy, Brona M., Prehn, Jochen H. M.
Publicado 2019

The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance

por Fitzgerald, Marie-Claire, O’Halloran, Philip J., Kerrane, Sean A., Ní Chonghaile, Triona, Connolly, Niamh M. C., Murphy, Brona M.
Publicado 2023

Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism

por Lincoln, Frank A., Imig, Dirke, Boccellato, Chiara, Juric, Viktorija, Noonan, Janis, Kontermann, Roland E., Allgöwer, Frank, Murphy, Brona M., Rehm, Markus
Publicado 2018

Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist

por Boccellato, Chiara, Kolbe, Emily, Peters, Nathalie, Juric, Viktorija, Fullstone, Gavin, Verreault, Maïté, Idbaih, Ahmed, Lamfers, Martine L. M., Murphy, Brona M., Rehm, Markus
Publicado 2021

Transcriptional CDK inhibitors, CYC065 and THZ1 promote Bim-dependent apoptosis in primary and recurrent GBM through cell cycle arrest and Mcl-1 downregulation

por Juric, Viktorija, Hudson, Lance, Fay, Joanna, Richards, Cathy E., Jahns, Hanne, Verreault, Maïté, Bielle, Franck, Idbaih, Ahmed, Lamfers, Martine L. M., Hopkins, Ann M., Rehm, Markus, Murphy, Brona M.
Publicado 2021

Implementing Patient-Derived Xenografts to Assess the Effectiveness of Cyclin-Dependent Kinase Inhibitors in Glioblastoma

por Noonan, Janis J., Jarzabek, Monika, Lincoln, Frank A., Cavanagh, Brenton L., Pariag, Arhona R., Juric, Viktorija, Young, Leonie S., Ligon, Keith L., Jahns, Hanne, Zheleva, Daniella, Prehn, Jochen H. M., Rehm, Markus, Byrne, Annette T., Murphy, Brona M.
Publicado 2019

PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistan...

por Davern, Maria, Fitzgerald, Marie-Claire, Buckley, Croí E., Heeran, Aisling B., Donlon, Noel E., McGrath, Jason, O’ Connell, Fiona, Deshpande, Malvika R., Hayes, Conall, MacDonald, Jamie, Sheppard, Andrew D., Reynolds, John V., Maher, Stephen G., Lynam-Lennon, Niamh, Murphy, Brona, Lysaght, Joanne
Publicado 2022

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

por Biswas, Archita, Salvucci, Manuela, Connor, Kate, Düssmann, Heiko, Carberry, Steven, Fichtner, Michael, King, Ellen, Murphy, Brona, O’Farrell, Alice C., Cryan, Jane, Beausang, Alan, Heffernan, Josephine, Cremona, Mattia, Hennessy, Bryan T., Clerkin, James, Sweeney, Kieron J., MacNally, Steve, Brett, Francesca, O’Halloran, Philip, Bacon, Orna, Furney, Simon, Verreault, Maite, Quissac, Emie, Bielle, Franck, Ahmed, Mohammed H., Idbaih, Ahmed, Leenstra, Sieger, Ntafoulis, Ioannis, Fabro, Federica, Lamfers, Martine, Golebiewska, Anna, Hertel, Frank, Niclou, Simone P., Yen, Romain Tching Chi, Kremer, Andreas, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, Lambrechts, Diether, Purushothama, Manasa Kalya, Kel, Alexander, Byrne, Annette T., Prehn, Jochen H.M.
Publicado 2023