p53, transcriptional repression and drug sensitivity: Fresh perspectives on an old activity

por Murphy, Maureen E.
Publicado 2010

Shifting the paradigms for tumor suppression: lessons from the p53 field

por Barnoud, Thibaut, Indeglia, Alexandra, Murphy, Maureen E.
Publicado 2021

Editorial: Double-Edged Swords: Genetic Factors That Influence the Pathogenesis of Both Metabolic Disease and Cancer

por Kung, Che-Pei, Murphy, Maureen E., Lu, Hua
Publicado 2019

CSF1 Is a Novel p53 Target Gene Whose Protein Product Functions in a Feed-Forward Manner to Suppress Apoptosis and Enhance p53-Mediated Growth Arrest

por Azzam, Gregory, Wang, Xuting, Bell, Douglas, Murphy, Maureen E.
Publicado 2013

Correction: CSF1 Is a Novel p53 Target Gene Whose Protein Product Functions in a Feed-Forward Manner to Suppress Apoptosis and Enhance p53-Mediated Growth Arrest

por Azzam, Gregory, Wang, Xuting, Bell, Douglas, Murphy, Maureen E.
Publicado 2013

Tumor cells containing the African-Centric S47 variant of TP53 show increased Warburg metabolism

por Barnoud, Thibaut, Parris, Joshua L.D., Murphy, Maureen E.
Publicado 2019

Common genetic variants in the TP53 pathway and their impact on cancer

por Barnoud, Thibaut, Parris, Joshua L D, Murphy, Maureen E
Publicado 2019

Editorial: Double-edged swords: Important factors connecting metabolic disorders and cancer development – from basic research to translational applications

por Kung, Che-Pei, Barnoud, Thibaut, Yao, Cong-Hui, Murphy, Maureen E.
Publicado 2023

Crystal Structure of the Stress-Inducible Human Heat Shock Protein 70 Substrate-Binding Domain in Complex with Peptide Substrate

por Zhang, Pingfeng, Leu, Julia I-Ju, Murphy, Maureen E., George, Donna L., Marmorstein, Ronen
Publicado 2014

Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket

por Leu, Julia I-Ju, Zhang, Pingfeng, Murphy, Maureen E., Marmorstein, Ronen, George, Donna L.
Publicado 2014

The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis

por Gnanapradeepan, Keerthana, Basu, Subhasree, Barnoud, Thibaut, Budina-Kolomets, Anna, Kung, Che-Pei, Murphy, Maureen E.
Publicado 2018

P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting

por Gokare, Prashanth, Finnberg, Niklas K., Abbosh, Phillip H., Dai, Jenny, Murphy, Maureen E., El-Deiry, Wafik S.
Publicado 2017

Identification and Characterization of Small Molecule Human Papillomavirus E6 Inhibitors

por Malecka, Kimberly A., Fera, Daniela, Schultz, David C., Hodawadekar, Santosh, Reichman, Melvin, Donover, Preston S., Murphy, Maureen E., Marmorstein, Ronen
Publicado 2014

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

por Gnanapradeepan, Keerthana, Indeglia, Alexandra, Stieg, David C., Clarke, Nicole, Shao, Chunlei, Dougherty, James F., Murali, Nivitha, Murphy, Maureen E.
Publicado 2022

Inhibition of stress-inducible HSP70 impairs mitochondrial proteostasis and function

por Leu, Julia I-Ju, Barnoud, Thibaut, Zhang, Gao, Tian, Tian, Wei, Zhi, Herlyn, Meenhard, Murphy, Maureen E., George, Donna L.
Publicado 2017

Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α

por Basu, Subhasree, Gnanapradeepan, Keerthana, Barnoud, Thibaut, Kung, Che-Pei, Tavecchio, Michele, Scott, Jeremy, Watters, Andrea, Chen, Qing, Kossenkov, Andrew V., Murphy, Maureen E.
Publicado 2018

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism

por Calderon, Abram, Soldan, Samantha S., De Leo, Alessandra, Deng, Zhong, Frase, Drew M., Anderson, Emma M., Zhang, Yue, Vladimirova, Olga, Lu, Fang, Leung, Jessica C., Murphy, Maureen E., Lieberman, Paul M.
Publicado 2020

African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin

por Singh, Kumar Sachin, Leu, Julia I-Ju, Barnoud, Thibaut, Vonteddu, Prashanthi, Gnanapradeepan, Keerthana, Lin, Cindy, Liu, Qin, Barton, James C., Kossenkov, Andrew V., George, Donna L., Murphy, Maureen E., Dotiwala, Farokh
Publicado 2020

Author Correction: African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin

por Singh, Kumar Sachin, Leu, Julia I-Ju, Barnoud, Thibaut, Vonteddu, Prashanthi, Gnanapradeepan, Keerthana, Lin, Cindy, Liu, Qin, Barton, James C., Kossenkov, Andrew V., George, Donna L., Murphy, Maureen E., Dotiwala, Farokh
Publicado 2020

The African-centric P47S Variant of TP53 Confers Immune Dysregulation and Impaired Response to Immune Checkpoint Inhibition

por Stieg, David C., Parris, Joshua L. D., Yang, Tyler Hong Loong, Mirji, Gauri, Reiser, Sarah Kim, Murali, Nivitha, Werts, Madison, Barnoud, Thibaut, Lu, David Y., Shinde, Rahul, Murphy, Maureen E., Claiborne, Daniel T.
Publicado 2023