Fragment-based drug discovery: opportunities for organic synthesis

por St. Denis, Jeffrey D., Hall, Richard J., Murray, Christopher W., Heightman, Tom D., Rees, David C.
Publicado 2020

Associations between Patient Global Assessment scores and pain, physical function, and fatigue in rheumatoid arthritis: a post hoc analysis of data from phase 3 trials of tofacitin...

por Strand, Vibeke, Kaine, Jeffrey, Alten, Rieke, Wallenstein, Gene, Diehl, Annette, Shi, Harry, Germino, Rebecca, Murray, Christopher W.
Publicado 2020

A versatile system to record cell-cell interactions

por Tang, Rui, Murray, Christopher W, Linde, Ian L, Kramer, Nicholas J, Lyu, Zhonglin, Tsai, Min K, Chen, Leo C, Cai, Hongchen, Gitler, Aaron D, Engleman, Edgar, Lee, Wonjae, Winslow, Monte M
Publicado 2020

LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer

por Murray, Christopher W., Brady, Jennifer J., Han, Mingqi, Cai, Hongchen, Tsai, Min K., Pierce, Sarah E., Cheng, Ran, Demeter, Janos, Feldser, David M., Jackson, Peter K., Shackelford, David B., Winslow, Monte M.
Publicado 2022

Crystal Structure of Human Soluble Adenylate Cyclase Reveals a Distinct, Highly Flexible Allosteric Bicarbonate Binding Pocket

por Saalau-Bethell, Susanne M, Berdini, Valerio, Cleasby, Anne, Congreve, Miles, Coyle, Joseph E, Lock, Victoria, Murray, Christopher W, O'Brien, M Alistair, Rich, Sharna J, Sambrook, Tracey, Vinkovic, Mladen, Yon, Jeff R, Jhoti, Harren
Publicado 2014

Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function

por Saalau-Bethell, Susanne M., Woodhead, Andrew J., Chessari, Gianni, Carr, Maria G., Coyle, Joseph, Graham, Brent, Hiscock, Steven D., Murray, Christopher W., Pathuri, Puja, Rich, Sharna J., Richardson, Caroline J., Williams, Pamela A., Jhoti, Harren
Publicado 2012

Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages

por Gonzalez, Michael A., Lu, Daniel R., Yousefi, Maryam, Kroll, Ashley, Lo, Chen Hao, Briseño, Carlos G., Watson, J. E. Vivienne, Novitskiy, Sergey, Arias, Vanessa, Zhou, Hong, Plata Stapper, Andres, Tsai, Min K., Ashkin, Emily L., Murray, Christopher W., Li, Chi-Ming, Winslow, Monte M., Tarbell, Kristin V.
Publicado 2023

A multiplexed in vivo approach to identify driver genes in small cell lung cancer

por Lee, Myung Chang, Cai, Hongchen, Murray, Christopher W., Li, Chuan, Shue, Yan Ting, Andrejka, Laura, He, Andy L., Holzem, Alessandra M.E., Drainas, Alexandros P., Ko, Julie H., Coles, Garry L., Kong, Christina, Zhu, Shirley, Zhu, ChunFang, Wang, Jason, van de Rijn, Matt, Petrov, Dmitri A., Winslow, Monte M., Sage, Julien
Publicado 2023