Dissection of the Transversus Abdominis Muscle for Whole-mount Neuromuscular Junction Analysis

por Murray, Lyndsay, Gillingwater, Thomas H, Kothary, Rashmi
Publicado 2014

Mouse models of SMA show divergent patterns of neuronal vulnerability and resilience

por Woschitz, Victoria, Mei, Irene, Hedlund, Eva, Murray, Lyndsay M.
Publicado 2022

The Smn-Independent Beneficial Effects of Trichostatin A on an Intermediate Mouse Model of Spinal Muscular Atrophy

por Liu, Hong, Yazdani, Armin, Murray, Lyndsay M., Beauvais, Ariane, Kothary, Rashmi
Publicado 2014

Transcriptional profiling of differentially vulnerable motor neurons at pre-symptomatic stage in the Smn(2b/-) mouse model of spinal muscular atrophy

por Murray, Lyndsay M., Beauvais, Ariane, Gibeault, Sabrina, Courtney, Natalie L., Kothary, Rashmi
Publicado 2015

Reduced P53 levels ameliorate neuromuscular junction loss without affecting motor neuron pathology in a mouse model of spinal muscular atrophy

por Courtney, Natalie L., Mole, Alannah J., Thomson, Alison K., Murray, Lyndsay M.
Publicado 2019

Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophy

por Bowerman, Melissa, Murray, Lyndsay M, Boyer, Justin G, Anderson, Carrie L, Kothary, Rashmi
Publicado 2012

Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology

por Bowerman, Melissa, Michalski, John-Paul, Beauvais, Ariane, Murray, Lyndsay M., DeRepentigny, Yves, Kothary, Rashmi
Publicado 2014

Early onset muscle weakness and disruption of muscle proteins in mouse models of spinal muscular atrophy

por Boyer, Justin G, Murray, Lyndsay M, Scott, Kyle, De Repentigny, Yves, Renaud, Jean-Marc, Kothary, Rashmi
Publicado 2013

Synaptic withdrawal following nerve injury is influenced by postnatal maturity, muscle‐specific properties, and the presence of underlying pathology in mice

por Mole, Alannah J., Bell, Sarah, Thomson, Alison K., Dissanayake, Kosala N., Ribchester, Richard R., Murray, Lyndsay M.
Publicado 2020

Myogenic program dysregulation is contributory to disease pathogenesis in spinal muscular atrophy

por Boyer, Justin G., Deguise, Marc-Olivier, Murray, Lyndsay M., Yazdani, Armin, De Repentigny, Yves, Boudreau-Larivière, Céline, Kothary, Rashmi
Publicado 2014

Induction of Cell Stress in Neurons from Transgenic Mice Expressing Yellow Fluorescent Protein: Implications for Neurodegeneration Research

por Comley, Laura H., Wishart, Thomas M., Baxter, Becki, Murray, Lyndsay M., Nimmo, Ailish, Thomson, Derek, Parson, Simon H., Gillingwater, Thomas H.
Publicado 2011

Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases

por Kline, Rachel A., Kaifer, Kevin A., Osman, Erkan Y., Carella, Francesco, Tiberi, Ariana, Ross, Jolill, Pennetta, Giuseppa, Lorson, Christian L., Murray, Lyndsay M.
Publicado 2017

Motor unit recovery following Smn restoration in mouse models of spinal muscular atrophy

por Comley, Laura H, Kline, Rachel A, Thomson, Alison K, Woschitz, Victoria, Landeros, Eric Villalón, Osman, Erkan Y, Lorson, Christian L, Murray, Lyndsay M
Publicado 2022

Alternative Splicing Events Are a Late Feature of Pathology in a Mouse Model of Spinal Muscular Atrophy

por Bäumer, Dirk, Lee, Sheena, Nicholson, George, Davies, Joanna L., Parkinson, Nicholas J., Murray, Lyndsay M., Gillingwater, Thomas H., Ansorge, Olaf, Davies, Kay E., Talbot, Kevin
Publicado 2009

PRMT inhibitor promotes SMN2 exon 7 inclusion and synergizes with nusinersen to rescue SMA mice

por Kordala, Anna J, Stoodley, Jessica, Ahlskog, Nina, Hanifi, Muhammad, Garcia Guerra, Antonio, Bhomra, Amarjit, Lim, Wooi Fang, Murray, Lyndsay M, Talbot, Kevin, Hammond, Suzan M, Wood, Matthew JA, Rinaldi, Carlo
Publicado 2023

Temporal and tissue-specific variability of SMN protein levels in mouse models of spinal muscular atrophy

por Groen, Ewout J N, Perenthaler, Elena, Courtney, Natalie L, Jordan, Crispin Y, Shorrock, Hannah K, van der Hoorn, Dinja, Huang, Yu-Ting, Murray, Lyndsay M, Viero, Gabriella, Gillingwater, Thomas H
Publicado 2018

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

por Kline, Rachel A., Dissanayake, Kosala N., Hurtado, Maica Llavero, Martínez, Nicolás W., Ahl, Alexander, Mole, Alannah J., Lamont, Douglas J., Court, Felipe A., Ribchester, Richard R., Wishart, Thomas M., Murray, Lyndsay M.
Publicado 2019

Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice

por Walter, Lisa M., Deguise, Marc-Olivier, Meijboom, Katharina E., Betts, Corinne A., Ahlskog, Nina, van Westering, Tirsa L.E., Hazell, Gareth, McFall, Emily, Kordala, Anna, Hammond, Suzan M., Abendroth, Frank, Murray, Lyndsay M., Shorrock, Hannah K., Prosdocimo, Domenick A., Haldar, Saptarsi M., Jain, Mukesh K., Gillingwater, Thomas H., Claus, Peter, Kothary, Rashmi, Wood, Matthew J.A., Bowerman, Melissa
Publicado 2018

Abnormal fatty acid metabolism is a core component of spinal muscular atrophy

por Deguise, Marc‐Olivier, Baranello, Giovanni, Mastella, Chiara, Beauvais, Ariane, Michaud, Jean, Leone, Alessandro, De Amicis, Ramona, Battezzati, Alberto, Dunham, Christopher, Selby, Kathryn, Warman Chardon, Jodi, McMillan, Hugh J., Huang, Yu‐Ting, Courtney, Natalie L., Mole, Alannah J., Kubinski, Sabrina, Claus, Peter, Murray, Lyndsay M., Bowerman, Melissa, Gillingwater, Thomas H., Bertoli, Simona, Parson, Simon H., Kothary, Rashmi
Publicado 2019

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins

por Hall, Emma A., Nahorski, Michael S., Murray, Lyndsay M., Shaheen, Ranad, Perkins, Emma, Dissanayake, Kosala N., Kristaryanto, Yosua, Jones, Ross A., Vogt, Julie, Rivagorda, Manon, Handley, Mark T., Mali, Girish R., Quidwai, Tooba, Soares, Dinesh C., Keighren, Margaret A., McKie, Lisa, Mort, Richard L., Gammoh, Noor, Garcia-Munoz, Amaya, Davey, Tracey, Vermeren, Matthieu, Walsh, Diana, Budd, Peter, Aligianis, Irene A., Faqeih, Eissa, Quigley, Alan J., Jackson, Ian J., Kulathu, Yogesh, Jackson, Mandy, Ribchester, Richard R., von Kriegsheim, Alex, Alkuraya, Fowzan S., Woods, C. Geoffrey, Maher, Eamonn R., Mill, Pleasantine
Publicado 2017