TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues—a comparative study of oligonucleotide length, design and...

por Murray, Sue, Ittig, Damian, Koller, Erich, Berdeja, Andres, Chappell, Alfred, Prakash, Thazha P., Norrbom, Michaela, Swayze, Eric E., Leumann, Christian J., Seth, Punit P.
Publicado 2012

Lineage 2 West Nile Virus as Cause of Fatal Neurologic Disease in Horses, South Africa

por Venter, Marietjie, Human, Stacey, Zaayman, Dewald, Gerdes, Gertruida H., Williams, June, Steyl, Johan, Leman, Patricia A., Paweska, Janusz Tadeusz, Setzkorn, Hildegard, Rous, Gavin, Murray, Sue, Parker, Rissa, Donnellan, Cynthia, Swanepoel, Robert
Publicado 2009

Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

por Prakash, Thazha P, Mullick, Adam E, Lee, Richard G, Yu, Jinghua, Yeh, Steve T, Low, Audrey, Chappell, Alfred E, Østergaard, Michael E, Murray, Sue, Gaus, Hans J, Swayze, Eric E, Seth, Punit P
Publicado 2019

Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data

por Viney, Nicholas J., Guo, Shuling, Tai, Li‐Jung, Baker, Brenda F., Aghajan, Mariam, Jung, Shiangtung W., Yu, Rosie Z., Booten, Sheri, Murray, Heather, Machemer, Todd, Burel, Sebastien, Murray, Sue, Buchele, Gustavo, Tsimikas, Sotirios, Schneider, Eugene, Geary, Richard S., Benson, Merrill D., Monia, Brett P.
Publicado 2020

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice

por Lindén, Daniel, Ahnmark, Andrea, Pingitore, Piero, Ciociola, Ester, Ahlstedt, Ingela, Andréasson, Anne-Christine, Sasidharan, Kavitha, Madeyski-Bengtson, Katja, Zurek, Magdalena, Mancina, Rosellina M., Lindblom, Anna, Bjursell, Mikael, Böttcher, Gerhard, Ståhlman, Marcus, Bohlooly-Y, Mohammad, Haynes, William G., Carlsson, Björn, Graham, Mark, Lee, Richard, Murray, Sue, Valenti, Luca, Bhanot, Sanjay, Åkerblad, Peter, Romeo, Stefano
Publicado 2019

Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates

por Østergaard, Michael E, Jackson, Michaela, Low, Audrey, E. Chappell, Alfred, G. Lee, Richard, Peralta, Rachel Q, Yu, Jinghua, Kinberger, Garth A, Dan, Amy, Carty, Rick, Tanowitz, Michael, Anderson, Patrick, Kim, Tae-Won, Fradkin, Linda, Mullick, Adam E, Murray, Sue, Rigo, Frank, Prakash, Thazha P, Bennett, C Frank, Swayze, Eric E, Gaus, Hans J, Seth, Punit P
Publicado 2019