Modeling fructose-load-induced hepatic de-novo lipogenesis by model simplification

por Allen, Richard J, Musante, Cynthia J
Publicado 2017

A quantitative systems pharmacology model of the pathophysiology and treatment of COVID-19 predicts optimal timing of pharmacological interventions

por Rao, Rohit, Musante, Cynthia J., Allen, Richard
Publicado 2023

A continuous-time Markov chain model of fibrosis progression in NAFLD and NASH

por Meyer, Lyndsey F., Musante, Cynthia J., Allen, Richard
Publicado 2023

Modeling is data driven: Use it for successful virtual patient generation

por Rieger, Theodore R., Allen, Richard J., Musante, Cynthia J.
Publicado 2021

A Quantitative Systems Pharmacology Model of Liver Lipid Metabolism for Investigation of Non-Alcoholic Fatty Liver Disease

por Rieger, Theodore R., Allen, Richard J., Musante, Cynthia J.
Publicado 2022

PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates

por Thompson, W. Clayton, Zhou, Yingjiang, Talukdar, Saswata, Musante, Cynthia J.
Publicado 2016

A Survey of Software Tool Utilization and Capabilities for Quantitative Systems Pharmacology: What We Have and What We Need

por Ermakov, Sergey, Schmidt, Brian J., Musante, Cynthia J., Thalhauser, Craig J.
Publicado 2019

A quantitative analysis of statistical power identifies obesity endpoints for improved in vivo preclinical study design

por Selimkhanov, Jangir, Thompson, W. Clayton, Guo, Juen, Hall, Kevin D., Musante, Cynthia J.
Publicado 2017

A Prototype QSP Model of the Immune Response to SARS‐CoV‐2 for Community Development

por Dai, Wei, Rao, Rohit, Sher, Anna, Tania, Nessy, Musante, Cynthia J., Allen, Richard
Publicado 2020

Sources of inter-individual variability leading to significant changes in anti-PD-1 and anti-PD-L1 efficacy identified in mouse tumor models using a QSP framework

por Leete, Jessica C., Zager, Michael G., Musante, Cynthia J., Shtylla, Blerta, Qiao, Wenlian
Publicado 2022

American Society for Clinical Pharmacology and Therapeutics 2019 Annual Meeting Pre‐Conferences

por Bai, Jane P.F., Musante, Cynthia J., Petanceska, Suzana, Zhang, Lei, Zhao, Liang, Zhao, Ping
Publicado 2019

Evaluation of a Mathematical Model of Rat Body Weight Regulation in Application to Caloric Restriction and Drug Treatment Studies

por Selimkhanov, Jangir, Thompson, W. Clayton, Patterson, Terrell A., Hadcock, John R., Scott, Dennis O., Maurer, Tristan S., Musante, Cynthia J.
Publicado 2016

End‐to‐end application of model‐informed drug development for ertugliflozin, a novel sodium‐glucose cotransporter 2 inhibitor

por Fediuk, Daryl J., Nucci, Gianluca, Dawra, Vikas K., Callegari, Ernesto, Zhou, Susan, Musante, Cynthia J., Liang, Yali, Sweeney, Kevin, Sahasrabudhe, Vaishali
Publicado 2021

Perspective on the State of Pharmacometrics and Systems Pharmacology Integration

por Trame, Mirjam N., Riggs, Matthew, Biliouris, Konstantinos, Marathe, Dhananjay, Mettetal, Jerome, Post, Teun M., Rizk, Matthew L., Visser, Sandra A. G., Musante, Cynthia J.
Publicado 2018

Requirements, expectations, challenges and opportunities associated with training the next generation of pharmacometricians

por Schmidt, Stephan, Vozmediano, Valvanera, Cristofoletti, Rodrigo, Kim, Sarah, Lin, Zhoumeng, de Moraes, Natalia, Azeredo, Francine, Cicali, Brian, Leuenberger, Hans, Brown, Joshua D., Jin, Jin Y., Musante, Cynthia J., Tannenbaum, Stacey, Wang, Yaning
Publicado 2023