Crystal Structures of Influenza A Virus Matrix Protein M1: Variations on a Theme

por Safo, Martin K., Musayev, Faik N., Mosier, Philip D., Zhou, Qibing, Xie, Hang, Desai, Umesh R.
Publicado 2014

Inactive mutants of human pyridoxine 5′‐phosphate oxidase: a possible role for a noncatalytic pyridoxal 5′‐phosphate tight binding site

por Ghatge, Mohini S., Karve, Sayali S., David, Tanya M. S., Ahmed, Mostafa H., Musayev, Faik N., Cunningham, Kendra, Schirch, Verne, Safo, Martin K.
Publicado 2016

Molecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase

por Aljahdali, Anfal S., Musayev, Faik N., Burgner, John W., Ghatge, Mohini S., Shekar, Vibha, Zhang, Yan, Omar, Abdelsattar M., Safo, Martin K.
Publicado 2022

Broad Spectrum Anti-Influenza Agents by Inhibiting Self-Association of Matrix Protein 1

por Mosier, Philip D., Chiang, Meng-Jung, Lin, Zhengshi, Gao, Yamei, Althufairi, Bashayer, Zhou, Qibing, Musayev, Faik, Safo, Martin K., Xie, Hang, Desai, Umesh R.
Publicado 2016

The Cryo-EM structure of AAV2 Rep68 in complex with ssDNA reveals a malleable AAA(+) machine that can switch between oligomeric states

por Santosh, Vishaka, Musayev, Faik N, Jaiswal, Rahul, Zárate-Pérez, Francisco, Vandewinkel, Bram, Dierckx, Caroline, Endicott, Molly, Sharifi, Kamyar, Dryden, Kelly, Henckaerts, Els, Escalante, Carlos R
Publicado 2020

Crystal Structures of Human Pyridoxal Kinase in Complex with the Neurotoxins, Ginkgotoxin and Theophylline: Insights into Pyridoxal Kinase Inhibition

por Gandhi, Amit K., Desai, Jigar V., Ghatge, Mohini S., di Salvo, Martino L., Di Biase, Stefano, Danso-Danquah, Richmond, Musayev, Faik N., Contestabile, Roberto, Schirch, Verne, Safo, Martin K.
Publicado 2012

Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication

por Chiang, Meng-Jung, Musayev, Faik N, Kosikova, Martina, Lin, Zhengshi, Gao, Yamei, Mosier, Philip D, Althufairi, Bashayer, Ye, Zhiping, Zhou, Qibing, Desai, Umesh R, Xie, Hang, Safo, Martin K
Publicado 2017

Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease

por Alhashimi, Rana T., Ghatge, Mohini S., Donkor, Akua K., Deshpande, Tanvi M., Anabaraonye, Nancy, Alramadhani, Dina, Danso-Danquah, Richmond, Huang, Boshi, Zhang, Yan, Musayev, Faik N., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2022

Crystallographic analysis of human hemoglobin elucidates the structural basis of the potent and dual antisickling activity of pyridyl derivatives of vanillin. Corrigendum

por Abdulmalik, Osheiza, Ghatge, Mohini S., Musayev, Faik N., Parikh, Apurvasena, Chen, Qiukan, Yang, Jisheng, Nnamani, Ijeoma, Danso-Danquah, Richmond, Eseonu, Dorothy N., Asakura, Toshio, Abraham, Donald J., Venitz, Jurgen, Safo, Martin K.
Publicado 2011

VZHE-039, a novel antisickling agent that prevents erythrocyte sickling under both hypoxic and anoxic conditions

por Abdulmalik, Osheiza, Pagare, Piyusha P., Huang, Boshi, Xu, Guoyan G., Ghatge, Mohini S., Xu, Xiaomeng, Chen, Qiukan, Anabaraonye, Nancy, Musayev, Faik N., Omar, Abdelsattar M., Venitz, Jürgen, Zhang, Yan, Safo, Martin K.
Publicado 2020

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

por Nakagawa, Akito, Ferrari, Michele, Schleifer, Grigorij, Cooper, Marissa K., Liu, Chen, Yu, Binglan, Berra, Lorenzo, Klings, Elizabeth S., Safo, Ronni S., Chen, Qiukan, Musayev, Faik N., Safo, Martin K., Abdulmalik, Osheiza, Bloch, Donald B., Zapol, Warren M.
Publicado 2018

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

por Huang, Boshi, Ghatge, Mohini S., Donkor, Akua K., Musayev, Faik N., Deshpande, Tanvi M., Al-Awadh, Mohammed, Alhashimi, Rana T., Zhu, Hongmei, Omar, Abdelsattar M., Telen, Marilyn J., Zhang, Yan, McMahon, Tim J., Abdulmalik, Osheiza, Safo, Martin K.
Publicado 2022

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

por Tramonti, Angela, Ghatge, Mohini S., Babor, Jill T., Musayev, Faik N., di Salvo, Martino Luigi, Barile, Anna, Colotti, Gianni, Giorgi, Alessandra, Paredes, Steven D., Donkor, Akua K., Al Mughram, Mohammed H., de Crécy‐Lagard, Valérie, Safo, Martin K., Contestabile, Roberto
Publicado 2022