Exploring PHD Fingers and H3K4me0 Interactions with Molecular Dynamics Simulations and Binding Free Energy Calculations: AIRE-PHD1, a Comparative Study

por Spiliotopoulos, Dimitrios, Spitaleri, Andrea, Musco, Giovanna
Publicado 2012

In silico derived small molecules targeting the finger-finger interaction between the histone lysine methyltransferase NSD1 and Nizp1 repressor

por Berardi, Andrea, Ghitti, Michela, Quilici, Giacomo, Musco, Giovanna
Publicado 2020

New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA

por Zucchelli, Chiara, Ferrari, Elena, Blasi, Francesco, Musco, Giovanna, Bruckmann, Chiara
Publicado 2017

The stem cell secretome and its role in brain repair

por Drago, Denise, Cossetti, Chiara, Iraci, Nunzio, Gaude, Edoardo, Musco, Giovanna, Bachi, Angela, Pluchino, Stefano
Publicado 2013

Identification of TMPRSS6 cleavage sites of hemojuvelin

por Rausa, Marco, Ghitti, Michela, Pagani, Alessia, Nai, Antonella, Campanella, Alessandro, Musco, Giovanna, Camaschella, Clara, Silvestri, Laura
Publicado 2015

Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

por Marino, Francesca, Mojumdar, Aditya, Zucchelli, Chiara, Bhardwaj, Amit, Buratti, Emanuele, Vindigni, Alessandro, Musco, Giovanna, Onesti, Silvia
Publicado 2016

Discovery of 5,5′-Methylenedi-2,3-Cresotic Acid as a Potent Inhibitor of the Chemotactic Activity of the HMGB1·CXCL12 Heterocomplex Using Virtual Screening and NMR Validation

por De Leo, Federica, Quilici, Giacomo, De Marchis, Francesco, Mantonico, Malisa Vittoria, Bianchi, Marco Emilio, Musco, Giovanna
Publicado 2020

dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking

por Spiliotopoulos, Dimitrios, Kastritis, Panagiotis L., Melquiond, Adrien S. J., Bonvin, Alexandre M. J. J., Musco, Giovanna, Rocchia, Walter, Spitaleri, Andrea
Publicado 2016

The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation

por Chignola, Francesca, Gaetani, Massimiliano, Rebane, Ana, Org, Tõnis, Mollica, Luca, Zucchelli, Chiara, Spitaleri, Andrea, Mannella, Valeria, Peterson, Pärt, Musco, Giovanna
Publicado 2009

A persulfidation-based mechanism controls aquaporin-8 conductance

por Bestetti, Stefano, Medraño-Fernandez, Iria, Galli, Mauro, Ghitti, Michela, Bienert, Gerd P., Musco, Giovanna, Orsi, Andrea, Rubartelli, Anna, Sitia, Roberto
Publicado 2018

Structural basis for PHD(V)C5HCH(NSD1)–C2HR(Nizp1) interaction: implications for Sotos syndrome

por Berardi, Andrea, Quilici, Giacomo, Spiliotopoulos, Dimitrios, Corral-Rodriguez, Maria Angeles, Martin-Garcia, Fernando, Degano, Massimo, Tonon, Giovanni, Ghitti, Michela, Musco, Giovanna
Publicado 2016

SMARCA5 interacts with NUP98-NSD1 oncofusion protein and sustains hematopoietic cells transformation

por Jevtic, Zivojin, Matafora, Vittoria, Casagrande, Francesca, Santoro, Fabio, Minucci, Saverio, Garre’, Massimilliano, Rasouli, Milad, Heidenreich, Olaf, Musco, Giovanna, Schwaller, Jürg, Bachi, Angela
Publicado 2022

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

por Org, Tõnis, Chignola, Francesca, Hetényi, Csaba, Gaetani, Massimiliano, Rebane, Ana, Liiv, Ingrid, Maran, Uko, Mollica, Luca, Bottomley, Matthew J, Musco, Giovanna, Peterson, Pärt
Publicado 2008

Metabolic determinants of the immune modulatory function of neural stem cells

por Drago, Denise, Basso, Veronica, Gaude, Edoardo, Volpe, Giulio, Peruzzotti-Jametti, Luca, Bachi, Angela, Musco, Giovanna, Andolfo, Annapaola, Frezza, Christian, Mondino, Anna, Pluchino, Stefano
Publicado 2016

AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome

por Gaetani, Massimiliano, Matafora, Vittoria, Saare, Mario, Spiliotopoulos, Dimitrios, Mollica, Luca, Quilici, Giacomo, Chignola, Francesca, Mannella, Valeria, Zucchelli, Chiara, Peterson, Pärt, Bachi, Angela, Musco, Giovanna
Publicado 2012

Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by (1)H HR-MAS NMR Metabolomics

por Tavel, Laurette, Fontana, Francesca, Garcia Manteiga, Josè Manuel, Mari, Silvia, Mariani, Elisabetta, Caneva, Enrico, Sitia, Roberto, Camnasio, Francesco, Marcatti, Magda, Cenci, Simone, Musco, Giovanna
Publicado 2016

Integrating a prospective pilot trial and patient-derived xenografts to trace metabolic changes associated with acute myeloid leukemia

por Carrabba, Matteo G., Tavel, Laurette, Oliveira, Giacomo, Forcina, Alessandra, Quilici, Giacomo, Nardelli, Francesca, Tresoldi, Cristina, Ambrosi, Alessandro, Ciceri, Fabio, Bernardi, Massimo, Vago, Luca, Musco, Giovanna
Publicado 2016

Defective Glucose Metabolism in Polycystic Kidney Disease Identifies A Novel Therapeutic Paradigm

por Rowe, Isaline, Chiaravalli, Marco, Mannella, Valeria, Ulisse, Valeria, Quilici, Giacomo, Pema, Monika, Song, Xuewen W., Xu, Hangxue, Mari, Silvia, Qian, Feng, Pei, York, Musco, Giovanna, Boletta, Alessandra
Publicado 2013

SP140L, an Evolutionarily Recent Member of the SP100 Family, Is an Autoantigen in Primary Biliary Cirrhosis

por Saare, Mario, Hämarik, Uku, Venta, Rainis, Panarina, Marina, Zucchelli, Chiara, Pihlap, Maire, Remm, Anu, Kisand, Kai, Toots, Urve, Möll, Kaidi, Salupere, Riina, Musco, Giovanna, Uibo, Raivo, Peterson, Pärt
Publicado 2015

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA

por Segalla, Simona, Pivetti, Silvia, Todoerti, Katia, Chudzik, Malgorzata Agata, Giuliani, Erica Claudia, Lazzaro, Federico, Volta, Viviana, Lazarevic, Dejan, Musco, Giovanna, Muzi-Falconi, Marco, Neri, Antonino, Biffo, Stefano, Tonon, Giovanni
Publicado 2015