BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells

por Ambrosini, Grazia, Sawle, Ashley D., Musi, Elgilda, Schwartz, Gary K.
Publicado 2015

The GPER Agonist LNS8801 Induces Mitotic Arrest and Apoptosis in Uveal Melanoma Cells

por Ambrosini, Grazia, Natale, Christopher A., Musi, Elgilda, Garyantes, Tina, Schwartz, Gary K.
Publicado 2023

Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models of sa...

por Patwardhan, Parag P., Ivy, Kathryn S., Musi, Elgilda, de Stanchina, Elisa, Schwartz, Gary K.
Publicado 2015

Impact of Combined mTOR and MEK Inhibition in Uveal Melanoma Is Driven by Tumor Genotype

por Ho, Alan L., Musi, Elgilda, Ambrosini, Grazia, Nair, Jayasree S., Deraje Vasudeva, Shyamprasad, de Stanchina, Elisa, Schwartz, Gary K.
Publicado 2012

Protein biomarkers for response to XPO1 inhibition in haematologic malignancies

por Totiger, Tulasigeri M., Chaudhry, Sana, Musi, Elgilda, Afaghani, Jumana, Montoya, Skye, Owusu‐Ansah, Frank, Lee, Stanley, Schwartz, Gary, Klimek, Virginia, Taylor, Justin
Publicado 2023

Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo

por Musi, Elgilda, Schwartz, Gary K., Yoo, Jae Hyuk, Odelberg, Shannon J., Li, Dean Y., Bonner, Michael Y., Selvakumar, Ponniah, Rao, Shikha, Gilbert, Linda C., Elsey, Justin, Arbiser, Jack L.
Publicado 2019

A Phase Ib Study of Sotrastaurin, a PKC Inhibitor, and Alpelisib, a PI3Kα Inhibitor, in Patients with Metastatic Uveal Melanoma

por Shoushtari, Alexander N., Khan, Shaheer, Komatsubara, Kimberly, Feun, Lynn, Acquavella, Nicolas, Singh-Kandah, Shahnaz, Negri, Tiffany, Nesson, Alexandra, Abbate, Kelly, Cremers, Serge, Musi, Elgilda, Ambrosini, Grazia, Lee, Shing, Schwartz, Gary K., Carvajal, Richard D.
Publicado 2021

Transcriptional analysis of metastatic uveal melanoma survival nominates NRP1 as a therapeutic target

por Bao, Riyue, Surriga, Oliver, Olson, Daniel J., Allred, Jacob B., Strand, Carrie A., Zha, Yuanyuan, Carll, Timothy, Labadie, Brian W., Bastos, Bruno R., Butler, Marcus, Hogg, David, Musi, Elgilda, Ambrosini, Grazia, Munster, Pamela, Schwartz, Gary K., Luke, Jason J.
Publicado 2020