Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

por Mutisya, Daniel, Selvam, Chelliah, Lunstad, Benjamin D., Pallan, Pradeep S., Haas, Amanda, Leake, Devin, Egli, Martin, Rozners, Eriks
Publicado 2014

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs

por Mutisya, Daniel, Hardcastle, Travis, Cheruiyot, Samwel K., Pallan, Pradeep S., Kennedy, Scott D., Egli, Martin, Kelley, Melissa L., Smith, Anja van Brabant, Rozners, Eriks
Publicado 2017

A novel siRNA–gemcitabine construct as a potential therapeutic for treatment of pancreatic cancer

por Simonenko, Vera, Lu, Xiaoyong, Roesch, Eric, Mutisya, Daniel, Shao, Chunbo, Sun, Qian, Patterson-Orazem, Athéna, McNair, Marcus, Shanmuganathan, Aranganathan, Lu, Patrick, Evans, David M
Publicado 2020