Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant

por Fiorani, Paola, Tesauro, Cinzia, Mancini, Giordano, Chillemi, Giovanni, D'A;nnessa, Ilda, Graziani, Grazia, Tentori, Lucio, Muzi, Alessia, Desideri, Alessandro
Publicado 2009

NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug

por Caporali, Simona, Levati, Lauretta, Graziani, Grazia, Muzi, Alessia, Atzori, Maria Grazia, Bonmassar, Enzo, Palmieri, Giuseppe, Ascierto, Paolo A, D’Atri, Stefania
Publicado 2012

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

por Tentori, Lucio, Ricci-Vitiani, Lucia, Muzi, Alessia, Ciccarone, Fabio, Pelacchi, Federica, Calabrese, Roberta, Runci, Daniele, Pallini, Roberto, Caiafa, Paola, Graziani, Grazia
Publicado 2014

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers

por Tesauro, Cinzia, Graziani, Grazia, Arnò, Barbara, Zuccaro, Laura, Muzi, Alessia, D’Annessa, Ilda, Santori, Elettra, Tentori, Lucio, Leonetti, Carlo, Fiorani, Paola, Desideri, Alessandro
Publicado 2014

Immunogenicity of COVID-eVax Delivered by Electroporation Is Moderately Impacted by Temperature and Molecular Isoforms

por D’Alessio, Federico, Lione, Lucia, Salvatori, Erika, Bucci, Federica, Muzi, Alessia, Roscilli, Giuseppe, Compagnone, Mirco, Pinto, Eleonora, Battistuzzi, Gianfranco, Conforti, Antonella, Aurisicchio, Luigi, Palombo, Fabio
Publicado 2023

The Nuts and Bolts of SARS-CoV-2 Spike Receptor-Binding Domain Heterologous Expression

por Maffei, Mariano, Montemiglio, Linda Celeste, Vitagliano, Grazia, Fedele, Luigi, Sellathurai, Shaila, Bucci, Federica, Compagnone, Mirco, Chiarini, Valerio, Exertier, Cécile, Muzi, Alessia, Roscilli, Giuseppe, Vallone, Beatrice, Marra, Emanuele
Publicado 2021

PARP-1 Modulates Amyloid Beta Peptide-Induced Neuronal Damage

por Martire, Sara, Fuso, Andrea, Rotili, Dante, Tempera, Italo, Giordano, Cesare, De Zottis, Ivana, Muzi, Alessia, Vernole, Patrizia, Graziani, Grazia, Lococo, Emanuela, Faraldi, Martina, Maras, Bruno, Scarpa, Sigfrido, Mosca, Luciana, d'Erme, Maria
Publicado 2013

A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats

por Conforti, Antonella, Sanchez, Elisa, Salvatori, Erika, Lione, Lucia, Compagnone, Mirco, Pinto, Eleonora, Palombo, Fabio, D’Acunto, Emanuela, Muzi, Alessia, Roscilli, Giuseppe, Sun, Yuhua, Viscount, Brian, Hayward, James, Shorrock, Clay, Diel, Diego G., Impellizeri, Joseph A., Aurisicchio, Luigi
Publicado 2023

A first-in-human trial on the safety and immunogenicity of COVID-eVax, a cellular response-skewed DNA vaccine against COVID-19

por Aurisicchio, Luigi, Brambilla, Nadia, Cazzaniga, Marina E., Bonfanti, Paolo, Milleri, Stefano, Ascierto, Paolo A., Capici, Serena, Vitalini, Cristina, Girolami, Federica, Giacovelli, Giampaolo, Caselli, Gianfranco, Visintin, Michela, Fanti, Francesca, Ghirri, Matteo, Conforti, Antonella, Compagnone, Mirco, Lione, Lucia, Salvatori, Erika, Pinto, Eleonora, Muzi, Alessia, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Manenti, Alessandro, Montomoli, Emanuele, Cadossi, Matteo, Rovati, Lucio C.
Publicado 2023

Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections

por Terreri, Sara, Piano Mortari, Eva, Vinci, Maria Rosaria, Russo, Cristina, Alteri, Claudia, Albano, Christian, Colavita, Francesca, Gramigna, Giulia, Agrati, Chiara, Linardos, Giulia, Coltella, Luana, Colagrossi, Luna, Deriu, Gloria, Ciofi Degli Atti, Marta, Rizzo, Caterina, Scarsella, Marco, Brugaletta, Rita, Camisa, Vincenzo, Santoro, Annapaola, Roscilli, Giuseppe, Pavoni, Emiliano, Muzi, Alessia, Magnavita, Nicola, Scutari, Rossana, Villani, Alberto, Raponi, Massimiliano, Locatelli, Franco, Perno, Carlo Federico, Zaffina, Salvatore, Carsetti, Rita
Publicado 2022

COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models

por Conforti, Antonella, Marra, Emanuele, Palombo, Fabio, Roscilli, Giuseppe, Ravà, Micol, Fumagalli, Valeria, Muzi, Alessia, Maffei, Mariano, Luberto, Laura, Lione, Lucia, Salvatori, Erika, Compagnone, Mirco, Pinto, Eleonora, Pavoni, Emiliano, Bucci, Federica, Vitagliano, Grazia, Stoppoloni, Daniela, Pacello, Maria Lucrezia, Cappelletti, Manuela, Ferrara, Fabiana Fosca, D’Acunto, Emanuela, Chiarini, Valerio, Arriga, Roberto, Nyska, Abraham, Di Lucia, Pietro, Marotta, Davide, Bono, Elisa, Giustini, Leonardo, Sala, Eleonora, Perucchini, Chiara, Paterson, Jemma, Ryan, Kathryn Ann, Challis, Amy-Rose, Matusali, Giulia, Colavita, Francesca, Caselli, Gianfranco, Criscuolo, Elena, Clementi, Nicola, Mancini, Nicasio, Groß, Rüdiger, Seidel, Alina, Wettstein, Lukas, Münch, Jan, Donnici, Lorena, Conti, Matteo, De Francesco, Raffaele, Kuka, Mirela, Ciliberto, Gennaro, Castilletti, Concetta, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Guidotti, Luca G., Rovati, Lucio, Iannacone, Matteo, Aurisicchio, Luigi
Publicado 2022