Targeting vascular inflammation through emerging methods and drug carriers

por Nong, Jia, Glassman, Patrick M., Muzykantov, Vladimir R.
Publicado 2022

Collaborative Enhancement of Antibody Binding to Distinct PECAM-1 Epitopes Modulates Endothelial Targeting

por Chacko, Ann-Marie, Nayak, Madhura, Greineder, Colin F., DeLisser, Horace M., Muzykantov, Vladimir R.
Publicado 2012

Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors

por Ramakrishnan, N., Tourdot, Richard W., Eckmann, David M., Ayyaswamy, Portonovo S., Muzykantov, Vladimir R., Radhakrishnan, Ravi
Publicado 2016

Red Blood Cell Anchoring Enables Targeted Transduction and Re‐Administration of AAV‐Mediated Gene Therapy

por Zhao, Zongmin, Kim, Jayoung, Suja, Vinny Chandran, Kapate, Neha, Gao, Yongsheng, Guo, Junling, Muzykantov, Vladimir R., Mitragotri, Samir
Publicado 2022

ICAM-1 Targeted Nanogels Loaded with Dexamethasone Alleviate Pulmonary Inflammation

por Coll Ferrer, M. Carme, Shuvaev, Vladimir V., Zern, Blaine J., Composto, Russell J., Muzykantov, Vladimir R., Eckmann, David M.
Publicado 2014

Immuno-imaging and -therapy in ovarian cancer and sarcoma with de novo single-chain fv-fc fusion protein targeting TEM1/CD248

por Li, Chunsheng, Wang, Junying, Matthaiou, Efthymia Iliana, Guo, Yi, Hu, Jia, Chacko, Ann Marie, Muzykantov, Vladimir R, Coukos, George
Publicado 2014

Targeting drug delivery in the vascular system: Focus on endothelium

por Glassman, Patrick M., Myerson, Jacob W., Ferguson, Laura T., Kiseleva, Raisa Y., Shuvaev, Vladimir V., Brenner, Jacob S., Muzykantov, Vladimir R.
Publicado 2020

Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury

por Lutton, Evan M., Farney, S. Katie, Andrews, Allison M., Shuvaev, Vladimir V., Chuang, Gwo-Yu, Muzykantov, Vladimir R., Ramirez, Servio H.
Publicado 2019

The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series)

por Brenner, Jacob S., Kiseleva, Raisa Yu., Glassman, Patrick M., Parhiz, Hamideh, Greineder, Colin F., Hood, Elizabeth D., Shuvaev, Vladimir V., Muzykantov, Vladimir R.
Publicado 2017

Vascular Drug Delivery Using Carrier Red Blood Cells: Focus on RBC Surface Loading and Pharmacokinetics

por Glassman, Patrick M., Villa, Carlos H., Ukidve, Anvay, Zhao, Zongmin, Smith, Paige, Mitragotri, Samir, Russell, Alan J., Brenner, Jacob S., Muzykantov, Vladimir R.
Publicado 2020

Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

por Lutton, Evan M., Razmpour, Roshanak, Andrews, Allison M., Cannella, Lee Anne, Son, Young-Jin, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Ramirez, Servio H.
Publicado 2017

Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9

por Khoshnejad, Makan, Brenner, Jacob S., Motley, William, Parhiz, Hamideh, Greineder, Colin F., Villa, Carlos H., Marcos-Contreras, Oscar A., Tsourkas, Andrew, Muzykantov, Vladimir R.
Publicado 2018

Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor

por Greineder, Colin F., Chacko, Ann-Marie, Zaytsev, Sergei, Zern, Blaine J., Carnemolla, Ronald, Hood, Elizabeth D., Han, Jingyan, Ding, Bi-Sen, Esmon, Charles T., Muzykantov, Vladimir R.
Publicado 2013

Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo

por Shuvaev, Vladimir V., Han, Jingyan, Tliba, Samira, Arguiri, Evguenia, Christofidou-Solomidou, Melpo, Ramirez, Servio H., Dykstra, Holly, Persidsky, Yuri, Atochin, Dmitriy N., Huang, Paul L., Muzykantov, Vladimir R.
Publicado 2013

Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1

por Kiseleva, Raisa, Greineder, Colin F., Villa, Carlos H., Hood, Elizabeth D., Shuvaev, Vladimir V., Sun, Jing, Chacko, Ann-Marie, Abraham, Valsamma, DeLisser, Horace M., Muzykantov, Vladimir R.
Publicado 2017

Development, optimization, and validation of novel anti-TEM1/CD248 affinity agent for optical imaging in cancer

por Li, Chunsheng, Wang, Junying, Hu, Jia, Feng, Yi, Hasegawa, Kosei, Peng, Xiaohui, Duan, Xingmei, Zhao, Aizhi, Mikitsh, John L., Muzykantov, Vladimir R., Chacko, Ann-Marie, Pryma, Daniel A., Dunn, Steven M., Coukos, George
Publicado 2014

Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium

por Goitre, Luca, DiStefano, Peter V., Moglia, Andrea, Nobiletti, Nicholas, Baldini, Eva, Trabalzini, Lorenza, Keubel, Julie, Trapani, Eliana, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Sarelius, Ingrid H., Retta, Saverio Francesco, Glading, Angela J.
Publicado 2017

Protocol for the MicroRESUS study: The impact of circulatory shock and resuscitation on microcirculatory function and mitochondrial respiration after cardiovascular surgery

por Greenwood, John C., Talebi, Fatima M., Jang, David H., Spelde, Audrey E., Kilbaugh, Todd J., Shofer, Frances S., Acker, Michael A., Augoustides, John G. T., Bakker, Jan, Meyer, Nuala J., Brenner, Jacob S., Muzykantov, Vladimir R., Abella, Benjamin S.
Publicado 2022

Topical nitroglycerin to detect reversible microcirculatory dysfunction in patients with circulatory shock after cardiovascular surgery: an observational study

por Greenwood, John C., Talebi, Fatima M., Jang, David H., Spelde, Audrey E., Tonna, Joseph E., Gutsche, Jacob T., Horak, Jiri, Acker, Michael A., Kilbaugh, Todd J., Shofer, Frances S., Augoustides, John G. T., Bakker, Jan, Brenner, Jacob S., Muzykantov, Vladimir R., Abella, Benjamin S.
Publicado 2022

Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)

por Parhiz, Hamideh, Brenner, Jacob S., Patel, Priyal N., Papp, Tyler E., Shahnawaz, Hamna, Li, Qin, Shi, Ruiqi, Zamora, Marco E., Yadegari, Amir, Marcos-Contreras, Oscar A., Natesan, Ambika, Pardi, Norbert, Shuvaev, Vladimir V., Kiseleva, Raisa, Myerson, Jacob W., Uhler, Thomas, Riley, Rachel S., Han, Xuexiang, Mitchell, Michael J., Lam, Kieu, Heyes, James, Weissman, Drew, Muzykantov, Vladimir R.
Publicado 2022