Tools for the Quality Control of Pharmaceutical Heparin

por Devlin, Anthony, Mycroft-West, Courtney, Procter, Patricia, Cooper, Lynsay, Guimond, Scott, Lima, Marcelo, Yates, Edwin, Skidmore, Mark
Publicado 2019

Molecular Changes in Dengue Envelope Protein Domain III upon Interaction with Glycosaminoglycans

por Hyatt, James G., Prévost, Sylvain, Devos, Juliette M., Mycroft-West, Courtney J., Skidmore, Mark A., Winter, Anja
Publicado 2020

Analysis of Heparin Samples by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy in the Solid State

por Devlin, Anthony J., Mycroft-West, Courtney J., Turnbull, Jeremy E., Lima, Marcelo Andrade de, Guerrini, Marco, Yates, Edwin A., Skidmore, Mark A.
Publicado 2023

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer’s Disease

por Mycroft-West, Courtney J., Cooper, Lynsay C., Devlin, Anthony J., Procter, Patricia, Guimond, Scott E., Guerrini, Marco, Fernig, David G., Lima, Marcelo A., Yates, Edwin A., Skidmore, Mark A.
Publicado 2019

Inhibition of BACE1, the β-secretase implicated in Alzheimer’s disease, by a chondroitin sulfate extract from Sardina pilchardus

por Mycroft-West, Courtney J., Devlin, Anthony J., Cooper, Lynsay C., Procter, Patricia, Miller, Gavin J., Fernig, David G., Guerrini, Marco, Guimond, Scott E., Lima, Marcelo A., Yates, Edwin A., Skidmore, Mark Andrew
Publicado 2020

Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease β Secretase, BACE1

por Mycroft-West, Courtney J., Devlin, Anthony J., Cooper, Lynsay C., Guimond, Scott E., Procter, Patricia, Guerrini, Marco, Miller, Gavin J., Fernig, David G., Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.
Publicado 2021

The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

por Davies, Scott P., Mycroft-West, Courtney J., Pagani, Isabel, Hill, Harriet J., Chen, Yen-Hsi, Karlsson, Richard, Bagdonaite, Ieva, Guimond, Scott E., Stamataki, Zania, De Lima, Marcelo Andrade, Turnbull, Jeremy E., Yang, Zhang, Vicenzi, Elisa, Skidmore, Mark A., Khanim, Farhat L., Richardson, Alan
Publicado 2021

Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain

por Schuurs, Zachariah P., Hammond, Edward, Elli, Stefano, Rudd, Timothy R., Mycroft-West, Courtney J., Lima, Marcelo A., Skidmore, Mark A., Karlsson, Richard, Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Ahmed, Yassir A., Richard, Derek J., Turnbull, Jeremy, Ferro, Vito, Coombe, Deirdre R., Gandhi, Neha S.
Publicado 2021

Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations

por Tree, Julia A., Turnbull, Jeremy E., Buttigieg, Karen R., Elmore, Michael J., Coombes, Naomi, Hogwood, John, Mycroft‐West, Courtney J., Lima, Marcelo A., Skidmore, Mark A., Karlsson, Richard, Chen, Yen‐Hsi, Yang, Zhang, Spalluto, Cosma Mirella, Staples, Karl J., Yates, Edwin A., Gray, Elaine, Singh, Dave, Wilkinson, Tom, Page, Clive P., Carroll, Miles W.
Publicado 2020

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

por Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung, Laidlaw, Stephen, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M. A., Watterson, Daniel, Khromykh, Alexander A., Suhrbier, Andreas, Carroll, Miles W., Trybala, Edward, Bergström, Tomas, Ferro, Vito, Skidmore, Mark A., Turnbull, Jeremy E.
Publicado 2022