Synthetic Lethality through the Lens of Medicinal Chemistry

por Myers, Samuel H., Ortega, Jose Antonio, Cavalli, Andrea
Publicado 2020

Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands

por Conole, Daniel, Myers, Samuel H., Mota, Filipa, Hobbs, Adrian J., Selwood, David L.
Publicado 2018

Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathway

por Valero, Teresa, Baillache, Daniel J., Fraser, Craig, Myers, Samuel H., Unciti-Broceta, Asier
Publicado 2020

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening

por Myers, Samuel H., Temps, Carolin, Houston, Douglas R., Brunton, Valerie G., Unciti-Broceta, Asier
Publicado 2018

Synthesis and Characterization of a Click-Assembled 18-Atom Macrocycle That Displays Selective AXL Kinase Inhibitory Activity

por Cruz-López, Olga, Temps, Carolin, Longo, Beatrice, Myers, Samuel H., Franco-Montalban, Francisco, Unciti-Broceta, Asier
Publicado 2019

A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C

por Smith, Robert J., Perez-Ternero, Cristina, Conole, Daniel, Martin, Capucine, Myers, Samuel H., Hobbs, Adrian J., Selwood, David L.
Publicado 2022

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

por Weiss, Jason T., Fraser, Craig, Rubio-Ruiz, Belén, Myers, Samuel H., Crispin, Richard, Dawson, John C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2014