SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site

por Mykytyn, Anna Z, Breugem, Tim I, Riesebosch, Samra, Schipper, Debby, van den Doel, Petra B, Rottier, Robbert J, Lamers, Mart M, Haagmans, Bart L
Publicado 2021

Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas

por Rodon, Jordi, Mykytyn, Anna Z., Cantero, Guillermo, Albulescu, Irina C., Bosch, Berend-Jan, Brix, Alexander, Audonnet, Jean-Christophe, Bensaid, Albert, Vergara-Alert, Júlia, Haagmans, Bart L., Segalés, Joaquim
Publicado 2022

Potency of Fusion-Inhibitory Lipopeptides against SARS-CoV-2 Variants of Concern

por Schmitz, Katharina S., Geers, Daryl, de Vries, Rory D., Bovier, T. Francesca, Mykytyn, Anna Z., Geurts van Kessel, Corine H., Haagmans, Bart L., Porotto, Matteo, de Swart, Rik L., Moscona, Anne
Publicado 2022

Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine

por Weskamm, Leonie M., Fathi, Anahita, Raadsen, Matthijs P., Mykytyn, Anna Z., Koch, Till, Spohn, Michael, Friedrich, Monika, Haagmans, Bart L., Becker, Stephan, Sutter, Gerd, Dahlke, Christine, Addo, Marylyn M.
Publicado 2022

Human airway cells prevent SARS-CoV-2 multibasic cleavage site cell culture adaptation

por Lamers, Mart M, Mykytyn, Anna Z, Breugem, Tim I, Wang, Yiquan, Wu, Douglas C, Riesebosch, Samra, van den Doel, Petra B, Schipper, Debby, Bestebroer, Theo, Wu, Nicholas C, Haagmans, Bart L
Publicado 2021

Glycosylated extracellular mucin domains protect against SARS-CoV-2 infection at the respiratory surface

por Chatterjee, Maitrayee, Huang, Liane Z. X., Mykytyn, Anna Z., Wang, Chunyan, Lamers, Mart M., Westendorp, Bart, Wubbolts, Richard W., van Putten, Jos P. M., Bosch, Berend-Jan, Haagmans, Bart L., Strijbis, Karin
Publicado 2023

Extended Viral Shedding of MERS-CoV Clade B Virus in Llamas Compared with African Clade C Strain

por Rodon, Jordi, Mykytyn, Anna Z., Te, Nigeer, Okba, Nisreen M.A., Lamers, Mart M., Pailler-García, Lola, Cantero, Guillermo, Albulescu, Irina, Bosch, Berend-Jan, Peiris, Malik, Bensaid, Albert, Vergara-Alert, Júlia, Haagmans, Bart L., Segalés, Joaquim
Publicado 2023

Antigenic mapping of emerging SARS-CoV-2 omicron variants BM.1.1.1, BQ.1.1, and XBB.1

por Mykytyn, Anna Z, Rosu, Miruna E, Kok, Adinda, Rissmann, Melanie, van Amerongen, Geert, Geurtsvankessel, Corine, de Vries, Rory D, Munnink, Bas B Oude, Smith, Derek J, Koopmans, Marion P G, Lamers, Mart M, Fouchier, Ron A M, Haagmans, Bart L
Publicado 2023

Susceptibility of rabbits to SARS-CoV-2

por Mykytyn, Anna Z., Lamers, Mart M., Okba, Nisreen M. A., Breugem, Tim I., Schipper, Debby, van den Doel, Petra B., van Run, Peter, van Amerongen, Geert, de Waal, Leon, Koopmans, Marion P. G., Stittelaar, Koert J., van den Brand, Judith M. A., Haagmans, Bart L.
Publicado 2021

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

por Beumer, Joep, Geurts, Maarten H., Lamers, Mart M., Puschhof, Jens, Zhang, Jingshu, van der Vaart, Jelte, Mykytyn, Anna Z., Breugem, Tim I., Riesebosch, Samra, Schipper, Debby, van den Doel, Petra B., de Lau, Wim, Pleguezuelos-Manzano, Cayetano, Busslinger, Georg, Haagmans, Bart L., Clevers, Hans
Publicado 2021

Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants

por Du, Wenjuan, Janssens, Rick, Mykytyn, Anna Z., Li, Wentao, Drabek, Dubravka, van Haperen, Rien, Chatziandreou, Marianthi, Rissmann, Melanie, van der Lee, Joline, van Dortmondt, Melissa, Martin, Itziar Serna, van Kuppeveld, Frank J. M., Hurdiss, Daniel L., Haagmans, Bart L., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2023

Interferon-α2 Auto-antibodies in Convalescent Plasma Therapy for COVID-19

por Raadsen, Matthijs P., Gharbharan, Arvind, Jordans, Carlijn C. E., Mykytyn, Anna Z., Lamers, Mart M., van den Doel, Petra B., Endeman, Henrik, van den Akker, Johannes P. C., GeurtsvanKessel, Corine H., Koopmans, Marion P. G., Rokx, Casper, Goeijenbier, Marco, van Gorp, Eric C. M., Rijnders, Bart J. A., Haagmans, Bart L.
Publicado 2021

An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells

por Lamers, Mart M, van der Vaart, Jelte, Knoops, Kèvin, Riesebosch, Samra, Breugem, Tim I, Mykytyn, Anna Z, Beumer, Joep, Schipper, Debby, Bezstarosti, Karel, Koopman, Charlotte D, Groen, Nathalie, Ravelli, Raimond B G, Duimel, Hans Q, Demmers, Jeroen A A, Verjans, Georges M G M, Koopmans, Marion P G, Muraro, Mauro J, Peters, Peter J, Clevers, Hans, Haagmans, Bart L
Publicado 2021

SARS-CoV-2 productively infects human gut enterocytes

por Lamers, Mart M., Beumer, Joep, van der Vaart, Jelte, Knoops, Kèvin, Puschhof, Jens, Breugem, Tim I., Ravelli, Raimond B. G., Paul van Schayck, J., Mykytyn, Anna Z., Duimel, Hans Q., van Donselaar, Elly, Riesebosch, Samra, Kuijpers, Helma J. H., Schippers, Debby, van de Wetering, Willine J., de Graaf, Miranda, Koopmans, Marion, Cuppen, Edwin, Peters, Peter J., Haagmans, Bart L., Clevers, Hans
Publicado 2020

Antigenic cartography of SARS-CoV-2 reveals that Omicron BA.1 and BA.2 are antigenically distinct

por Mykytyn, Anna Z., Rissmann, Melanie, Kok, Adinda, Rosu, Miruna E., Schipper, Debby, Breugem, Tim I., van den Doel, Petra B., Chandler, Felicity, Bestebroer, Theo, de Wit, Maurice, van Royen, Martin E., Molenkamp, Richard, Oude Munnink, Bas B., de Vries, Rory D., GeurtsvanKessel, Corine, Smith, Derek J., Koopmans, Marion P. G., Rockx, Barry, Lamers, Mart M., Fouchier, Ron, Haagmans, Bart L.
Publicado 2022

Divergent SARS CoV-2 Omicron-reactive T- and B cell responses in COVID-19 vaccine recipients

por GeurtsvanKessel, Corine H., Geers, Daryl, Schmitz, Katharina S., Mykytyn, Anna Z., Lamers, Mart M, Bogers, Susanne, Scherbeijn, Sandra, Gommers, Lennert, Sablerolles, Roos S.G., Nieuwkoop, Nella N., Rijsbergen, Laurine C., van Dijk, Laura L.A., de Wilde, Janet, Alblas, Kimberley, Breugem, Tim I., Rijnders, Bart J.A., de Jager, Herbert, Weiskopf, Daniela, van der Kuy, P. Hugo M., Sette, Alessandro, Koopmans, Marion P.G., Grifoni, Alba, Haagmans, Bart L., de Vries, Rory D.
Publicado 2022

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern

por Du, Wenjuan, Hurdiss, Daniel L., Drabek, Dubravka, Mykytyn, Anna Z., Kaiser, Franziska K., González-Hernández, Mariana, Muñoz-Santos, Diego, Lamers, Mart M., van Haperen, Rien, Li, Wentao, Drulyte, Ieva, Wang, Chunyan, Sola, Isabel, Armando, Federico, Beythien, Georg, Ciurkiewicz, Malgorzata, Baumgärtner, Wolfgang, Guilfoyle, Kate, Smits, Tony, van der Lee, Joline, van Kuppeveld, Frank J.M., van Amerongen, Geert, Haagmans, Bart L., Enjuanes, Luis, Osterhaus, Albert D.M.E., Grosveld, Frank, Bosch, Berend-Jan
Publicado 2022

Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera

por Mühlemann, Barbara, Wilks, Samuel H, Baracco, Lauren, Bekliz, Meriem, Carreño, Juan Manuel, Corman, Victor M, Davis-Gardner, Meredith E., Dejnirattisai, Wanwisa, Diamond, Michael S, Douek, Daniel C., Drosten, Christian, Eckerle, Isabella, Edara, Venkata-Viswanadh, Ellis, Madison, Fouchier, Ron A M, Frieman, Matthew, Godbole, Sucheta, Haagmans, Bart, Halfmann, Peter J, Henry, Amy R, Jones, Terry C, Katzelnick, Leah C, Kawaoka, Yoshihiro, Kimpel, Janine, Krammer, Florian, Lai, Lilin, Liu, Chang, Lusvarghi, Sabrina, Meyer, Benjamin, Mongkolsapaya, Juthathip, Montefiori, David C, Mykytyn, Anna, Netzl, Antonia, Pollett, Simon, Rössler, Annika, Screaton, Gavin R, Shen, Xiaoying, Sigal, Alex, Simon, Viviana, Subramanian, Rahul, Supasa, Piyada, Suthar, Mehul, Türeli, Sina, Wang, Wei, Weiss, Carol D, Smith, Derek J
Publicado 2023

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

por Brouwer, Philip J.M., Brinkkemper, Mitch, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Grobben, Marloes, Claireaux, Mathieu, de Gast, Marlon, Marlin, Romain, Chesnais, Virginie, Diry, Ségolène, Allen, Joel D., Watanabe, Yasunori, Giezen, Julia M., Kerster, Gius, Turner, Hannah L., van der Straten, Karlijn, van der Linden, Cynthia A., Aldon, Yoann, Naninck, Thibaut, Bontjer, Ilja, Burger, Judith A., Poniman, Meliawati, Mykytyn, Anna Z., Okba, Nisreen M.A., Schermer, Edith E., van Breemen, Marielle J., Ravichandran, Rashmi, Caniels, Tom G., van Schooten, Jelle, Kahlaoui, Nidhal, Contreras, Vanessa, Lemaître, Julien, Chapon, Catherine, Fang, Raphaël Ho Tsong, Villaudy, Julien, Sliepen, Kwinten, van der Velden, Yme U., Haagmans, Bart L., de Bree, Godelieve J., Ginoux, Eric, Ward, Andrew B., Crispin, Max, King, Neil P., van der Werf, Sylvie, van Gils, Marit J., Le Grand, Roger, Sanders, Rogier W.
Publicado 2021