Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin s...

por Myllykoski, Matti, Kursula, Petri
Publicado 2010

Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

por Myllykoski, Matti, Kursula, Petri
Publicado 2017

Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally twinned crystals

por Ponna, Srinivas Kumar, Myllykoski, Matti, Kursula, Petri
Publicado 2018

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation

por Myllykoski, Matti, Raasakka, Arne, Han, Huijong, Kursula, Petri
Publicado 2012

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

por Muruganandam, Gopinath, Raasakka, Arne, Myllykoski, Matti, Kursula, Inari, Kursula, Petri
Publicado 2017

Crystallographic Analysis of the Reaction Cycle of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family

por Myllykoski, Matti, Raasakka, Arne, Lehtimäki, Mari, Han, Huijong, Kursula, Inari, Kursula, Petri
Publicado 2013

Charge Isomers of Myelin Basic Protein: Structure and Interactions with Membranes, Nucleotide Analogues, and Calmodulin

por Wang, Chaozhan, Neugebauer, Ute, Bürck, Jochen, Myllykoski, Matti, Baumgärtel, Peter, Popp, Jürgen, Kursula, Petri
Publicado 2011

Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase

por Raasakka, Arne, Myllykoski, Matti, Laulumaa, Saara, Lehtimäki, Mari, Härtlein, Michael, Moulin, Martine, Kursula, Inari, Kursula, Petri
Publicado 2015

Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains

por Myllykoski, Matti, Sutinen, Aleksi, Koski, M. Kristian, Kallio, Juha P., Raasakka, Arne, Myllyharju, Johanna, Wierenga, Rik K., Koivunen, Peppi
Publicado 2020

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

por Snaidero, Nicolas, Velte, Caroline, Myllykoski, Matti, Raasakka, Arne, Ignatev, Alexander, Werner, Hauke B., Erwig, Michelle S., Möbius, Wiebke, Kursula, Petri, Nave, Klaus-Armin, Simons, Mikael
Publicado 2017

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

por Raasakka, Arne, Ruskamo, Salla, Kowal, Julia, Barker, Robert, Baumann, Anne, Martel, Anne, Tuusa, Jussi, Myllykoski, Matti, Bürck, Jochen, Ulrich, Anne S., Stahlberg, Henning, Kursula, Petri
Publicado 2017

Molecular structure and function of myelin protein P0 in membrane stacking

por Raasakka, Arne, Ruskamo, Salla, Kowal, Julia, Han, Huijong, Baumann, Anne, Myllykoski, Matti, Fasano, Anna, Rossano, Rocco, Riccio, Paolo, Bürck, Jochen, Ulrich, Anne S., Stahlberg, Henning, Kursula, Petri
Publicado 2019

HIDEA syndrome is caused by biallelic, pathogenic, rare or founder P4HTM variants impacting the active site or the overall stability of the P4H‐TM protein

por Kraatari‐Tiri, Minna, Soikkonen, Leila, Myllykoski, Matti, Jamshidi, Yalda, Karimiani, Ehsan G., Komulainen‐Ebrahim, Jonna, Kallankari, Hanna, Mignot, Cyril, Depienne, Christel, Keren, Boris, Nougues, Marie‐Christine, Alsahlawi, Zahra, Romito, Antonio, Martini, Javier, Toosi, Mehran B., Carroll, Christopher J., Tripolszki, Kornelia, Bauer, Peter, Uusimaa, Johanna, Bertoli‐Avella, Aida M., Koivunen, Peppi, Rahikkala, Elisa
Publicado 2022

Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome)

por Rahikkala, Elisa, Myllykoski, Matti, Hinttala, Reetta, Vieira, Päivi, Nayebzadeh, Naemeh, Weiss, Simone, Plomp, Astrid S., Bittner, Reginald E., Kurki, Mitja I., Kuismin, Outi, Lewis, Andrea M., Väisänen, Marja-Leena, Kokkonen, Hannaleena, Westermann, Jonne, Bernert, Günther, Tuominen, Hannu, Palotie, Aarno, Aaltonen, Lauri, Yang, Yaping, Potocki, Lorraine, Moilanen, Jukka, van Koningsbruggen, Silvana, Wang, Xia, Schmidt, Wolfgang M., Koivunen, Peppi, Uusimaa, Johanna
Publicado 2019

Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis

por Delamare, Marine, Le Roy, Amandine, Pacault, Mathilde, Schmitt, Loïc, Garrec, Céline, Maaziz, Nada, Myllykoski, Matti, Rimbert, Antoine, Karaghiannis, Valéna, Aral, Bernard, Catherwood, Mark, Airaud, Fabrice, Mansour-Hendili, Lamisse, Hoogewijs, David, Peroni, Edoardo, Idriss, Salam, Lesieur, Valentine, Caillaud, Amandine, Si-Tayeb, Karim, Chariau, Caroline, Gaignerie, Anne, Rab, Minke, Haferlach, Torsten, Meggendorfer, Manja, Bézieau, Stéphane, Benetti, Andrea, Casadevall, Nicole, Hirsch, Pierre, Rose, Christian, Wemeau, Mathieu, Galacteros, Frédéric, Cassinat, Bruno, Bellosillo, Beatriz, Bento, Celeste, van Wijk, Richard, Petrides, Petro E., Randi, Maria Luigia, McMullin, Mary Frances, Koivunen, Peppi, consortium, ECYT-3, Girodon, François, Gardie, Betty
Publicado 2023