A randomized, double‐blind, single‐dose, three‐arm, parallel group study to determine pharmacokinetic similarity of ABP 959 and eculizumab (Soliris(®)) in healthy male subjects...

por Chow, Vincent, Pan, Jean, Chien, David, Mytych, Daniel T., Hanes, Vladimir
Publicado 2020

Assessment of romiplostim immunogenicity in adult patients in clinical trials and in a global postmarketing registry

por Mytych, Daniel T., Park, Joseph K., Kim, June, Barger, Troy E., Boshier, Andy, Jawa, Vibha, Kuter, David J.
Publicado 2020

Immunogenicity assessment of bispecific antibody-based immunotherapy in oncology

por Zhou, Yanchen, Penny, Hweixian L, Kroenke, Mark A, Bautista, Bianca, Hainline, Kelly, Chea, Lynette S, Parnes, Jane, Mytych, Daniel T
Publicado 2022

Assessment of romiplostim immunogenicity in pediatric patients in clinical trials and in a global postmarketing registry

por Bowers, Charles, Mytych, Daniel T., Lawrence, Tatiana, Wang, Kejia, Barger, Troy E., Eisen, Melissa, Bennett, Carolyn M., Tarantino, Michael D.
Publicado 2021

Safety, tolerability, pharmacokinetics, and efficacy of AMG 403, a human anti-nerve growth factor monoclonal antibody, in two phase I studies with healthy volunteers and knee osteo...

por Gow, Jason M., Tsuji, Wayne H., Williams, Gary J., Mytych, Daniel, Sciberras, David, Searle, Shawn L., Mant, Tim, Gibbs, John P.
Publicado 2015

Characterization and root cause analysis of immunogenicity to pasotuxizumab (AMG 212), a prostate-specific membrane antigen-targeting bispecific T-cell engager therapy

por Penny, Hweixian Leong, Hainline, Kelly, Theoharis, Nathaniel, Wu, Bin, Brandl, Christian, Webhofer, Christian, McComb, Mason, Wittemer-Rump, Sabine, Koca, Gökben, Stienen, Sabine, Bargou, Ralf C., Hummel, Horst-Dieter, Loidl, Wolfgang, Grüllich, Carsten, Eggert, Tobias, Tran, Ben, Mytych, Daniel T.
Publicado 2023

Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target

por Kroenke, Mark A., Barger, Troy E., Hu, Jenny, Miller, Mieke Jill, Kalenian, Kevin, He, Lidong, Hsu, Hailing, Bartley, Yessenia, Chow, Vincent Fung-Sing, Teixeira dos Santos, Marcia Cristina, Sullivan, Barbara A., Cheng, Laurence E., Parnes, Jane R., Padaki, Rupa, Kuhns, Scott, Mytych, Daniel T.
Publicado 2021