Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

por Myzithras, Maria, Lin, Siqi, Radden, Legairre, Hess Kenny, Cynthia, Cai, Zheng, MacDonald, Angus, Binetti, Ralph, Marlow, Michael, Fracasso, Paul, Gibson, Glenn, Bartlett, Christina, Hawkins, Julie, Hansel, Steven
Publicado 2022

Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn

por Yang, Danlin, Giragossian, Craig, Castellano, Steven, Lasaro, Marcio, Xiao, Haiguang, Saraf, Himanshu, Hess Kenny, Cynthia, Rybina, Irina, Huang, Zhong-Fu, Ahlberg, Jennifer, Bigwarfe, Tammy, Myzithras, Maria, Waltz, Erica, Roberts, Simon, Kroe-Barrett, Rachel, Singh, Sanjaya
Publicado 2017

Retrospective analysis of model-based predictivity of human pharmacokinetics for anti-IL-36R monoclonal antibody MAB92 using a rat anti-mouse IL-36R monoclonal antibody and RNA exp...

por Ahlberg, Jennifer, Giragossian, Craig, Li, Hua, Myzithras, Maria, Raymond, Ernie, Caviness, Gary, Grimaldi, Christine, Brown, Su-Ellen, Perez, Rocio, Yang, Danlin, Kroe-Barrett, Rachel, Joseph, David, Pamulapati, Chandrasena, Coble, Kelly, Ruus, Peter, Woska, Joseph R., Ganesan, Rajkumar, Hansel, Steven, Mbow, M. Lamine
Publicado 2019