A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells

por Wu, Su, Näär, Anders M.
Publicado 2019

SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait

por Wu, Su, Näär, Anders M.
Publicado 2019

Differential Roles of Transcriptional Mediator Subunits in Regulation of Multidrug Resistance Gene Expression in Saccharomyces cerevisiae

por Shahi, Puja, Gulshan, Kailash, Näär, Anders M., Moye-Rowley, W. Scott
Publicado 2010

A Role for FACT in Repopulation of Nucleosomes at Inducible Genes

por Voth, Warren P., Takahata, Shinya, Nishikawa, Joy L., Metcalfe, Benjamin M., Näär, Anders M., Stillman, David J.
Publicado 2014

Structure of the VP16 Transactivator Target in ARC/Mediator

por Milbradt, Alexander G., Kulkarni, Madhura, Yi, Tingfang, Takeuchi, Koh, Sun, Zhen-Yu J., Luna, Rafael E., Selenko, Philipp, Näär, Anders M., Wagner, Gerhard
Publicado 2011

Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells

por Lan, Tammy C. T., Allan, Matty F., Malsick, Lauren E., Woo, Jia Z., Zhu, Chi, Zhang, Fengrui, Khandwala, Stuti, Nyeo, Sherry S. Y., Sun, Yu, Guo, Junjie U., Bathe, Mark, Näär, Anders, Griffiths, Anthony, Rouskin, Silvi
Publicado 2022

MicroRNA-22 Is a Key Regulator of Lipid and Metabolic Homeostasis

por Panella, Riccardo, Petri, Andreas, Desai, Bhavna N., Fagoonee, Sharmila, Cotton, Cody A., Nguyen, Piercen K., Lundin, Eric M., Wagshal, Alexandre, Wang, Da-Zhi, Näär, Anders M., Vlachos, Ioannis S., Maratos-Flier, Eleftheria, Altruda, Fiorella, Kauppinen, Sakari, Paolo Pandolfi, Pier
Publicado 2023

Identification of miR-148a as a novel regulator of cholesterol metabolism

por Goedeke, Leigh, Rotllan, Noemi, Canfrán-Duque, Alberto, Aranda, Juan F., Ramírez, Cristina M., Araldi, Elisa, Lin, Chin-Sheng, Anderson, Norma N., Wagschal, Alexandre, de Cabo, Rafael, Horton, Jay D., Lasunción, Miguel A., Näär, Anders M., Suárez, Yajaira, Fernández-Hernando, Carlos
Publicado 2015

Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence

por Sedic, Maja, Skibinski, Adam, Brown, Nelson, Gallardo, Mercedes, Mulligan, Peter, Martinez, Paula, Keller, Patricia J., Glover, Eugene, Richardson, Andrea L., Cowan, Janet, Toland, Amanda E., Ravichandran, Krithika, Riethman, Harold, Naber, Stephen P., Näär, Anders M., Blasco, Maria A., Hinds, Philip W., Kuperwasser, Charlotte
Publicado 2015

Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction

por Nishikawa, Joy L., Boeszoermenyi, Andras, Vale-Silva, Luis A., Torelli, Riccardo, Posteraro, Brunella, Sohn, Yoo-Jin, Ji, Fei, Gelev, Vladimir, Sanglard, Dominique, Sanguinetti, Maurizio, Sadreyev, Ruslan I., Mukherjee, Goutam, Bhyravabhotla, Jayaram, Buhrlage, Sara J., Gray, Nathanael S., Wagner, Gerhard, Näär, Anders M., Arthanari, Haribabu
Publicado 2016

An intranasal ASO therapeutic targeting SARS-CoV-2

por Zhu, Chi, Lee, Justin Y., Woo, Jia Z., Xu, Lei, Nguyenla, Xammy, Yamashiro, Livia H., Ji, Fei, Biering, Scott B., Van Dis, Erik, Gonzalez, Federico, Fox, Douglas, Wehri, Eddie, Rustagi, Arjun, Pinsky, Benjamin A., Schaletzky, Julia, Blish, Catherine A., Chiu, Charles, Harris, Eva, Sadreyev, Ruslan I., Stanley, Sarah, Kauppinen, Sakari, Rouskin, Silvi, Näär, Anders M.
Publicado 2022

Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells

por Nguyenla, Xammy, Wehri, Eddie, Van Dis, Erik, Biering, Scott B., Yamashiro, Livia H., Zhu, Chi, Stroumza, Julien, Dugast-Darzacq, Claire, Graham, Thomas G. W., Wang, Xuanting, Jockusch, Steffen, Tao, Chuanjuan, Chien, Minchen, Xie, Wei, Patel, Dinshaw J., Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas, Russo, James J., Ju, Jingyue, Näär, Anders M., Stanley, Sarah, Schaletzky, Julia
Publicado 2022

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

por Biering, Scott B., Gomes de Sousa, Francielle Tramontini, Tjang, Laurentia V., Pahmeier, Felix, Zhu, Chi, Ruan, Richard, Blanc, Sophie F., Patel, Trishna S., Worthington, Caroline M., Glasner, Dustin R., Castillo-Rojas, Bryan, Servellita, Venice, Lo, Nicholas T. N., Wong, Marcus P., Warnes, Colin M., Sandoval, Daniel R., Clausen, Thomas Mandel, Santos, Yale A., Fox, Douglas M., Ortega, Victoria, Näär, Anders M., Baric, Ralph S., Stanley, Sarah A., Aguilar, Hector C., Esko, Jeffrey D., Chiu, Charles Y., Pak, John E., Beatty, P. Robert, Harris, Eva
Publicado 2022

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

por Gorgulla, Christoph, Padmanabha Das, Krishna M., Leigh, Kendra E., Cespugli, Marco, Fischer, Patrick D., Wang, Zi-Fu, Tesseyre, Guilhem, Pandita, Shreya, Shnapir, Alec, Calderaio, Anthony, Gechev, Minko, Rose, Alexander, Lewis, Noam, Hutcheson, Colin, Yaffe, Erez, Luxenburg, Roni, Herce, Henry D., Durmaz, Vedat, Halazonetis, Thanos D., Fackeldey, Konstantin, Patten, Justin J., Chuprina, Alexander, Dziuba, Igor, Plekhova, Alla, Moroz, Yurii, Radchenko, Dmytro, Tarkhanova, Olga, Yavnyuk, Irina, Gruber, Christian, Yust, Ryan, Payne, Dave, Näär, Anders M., Namchuk, Mark N., Davey, Robert A., Wagner, Gerhard, Kinney, Jamie, Arthanari, Haribabu
Publicado 2020

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

por Gorgulla, Christoph, Padmanabha Das, Krishna M., Leigh, Kendra E., Cespugli, Marco, Fischer, Patrick D., Wang, Zi-Fu, Tesseyre, Guilhem, Pandita, Shreya, Shnapir, Alec, Calderaio, Anthony, Gechev, Minko, Rose, Alexander, Lewis, Noam, Hutcheson, Colin, Yaffe, Erez, Luxenburg, Roni, Herce, Henry D., Durmaz, Vedat, Halazonetis, Thanos D., Fackeldey, Konstantin, Patten, J.J., Chuprina, Alexander, Dziuba, Igor, Plekhova, Alla, Moroz, Yurii, Radchenko, Dmytro, Tarkhanova, Olga, Yavnyuk, Irina, Gruber, Christian, Yust, Ryan, Payne, Dave, Näär, Anders M., Namchuk, Mark N., Davey, Robert A., Wagner, Gerhard, Kinney, Jamie, Arthanari, Haribabu
Publicado 2021